World's Best Scientists 2026 revealed!
Tomoyoshi Soga

Tomoyoshi Soga

D-Index & Metrics

Chemistry

D-Index
82
Citations
32175
World Ranking
3038
National Ranking
173

Biology and Biochemistry

D-Index
92
Citations
38463
World Ranking
2179
National Ranking
127

Overview

Tomoyoshi Soga is affiliated with Keio University in Japan and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans multiple specialized areas including molecular biology, physiology, cancer research, oncology, and immunology.

The main research topics covered by Tomoyoshi Soga include:

  • Metabolomics and Mass Spectrometry Studies
  • Cancer, Hypoxia, and Metabolism
  • Adipose Tissue and Metabolism
  • Diet and Metabolism Studies
  • Epigenetics and DNA Methylation
  • RNA Modifications and Cancer
  • Gut Microbiota and Health

Prominent recent papers authored by or involving Tomoyoshi Soga include:

  • "Gut microbiota depletion by chronic antibiotic treatment alters the sleep/wake architecture and sleep EEG power spectra in mice," 2020, published in Scientific Reports
  • "SGLT2 inhibition eliminates senescent cells and alleviates pathological aging," 2024, published in Nature Aging
  • "Amino acid transporters as emerging therapeutic targets in cancer," 2021, published in Cancer Science
  • "The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia," 2021, published in Current Biology
  • "Insulin signaling requires glucose to promote lipid anabolism in adipocytes," 2020, published in Journal of Biological Chemistry

Frequent co-authors who have collaborated with Tomoyoshi Soga on multiple occasions include:

  • Akiyoshi Hirayama
  • Masaru Tomita
  • Masahiro Sugimoto
  • Shinya Kuroda
  • Shinji Fukuda

Tomoyoshi Soga has published regularly in key scientific venues. These include:

  • Scientific Reports (12 publications)
  • iScience (10 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (10 publications)
  • Cell Reports (8 publications)
  • Metabolites (8 publications)

The scope of Soga's work is interdisciplinary, emphasizing the application of biochemical and molecular biology techniques to study complex physiological and pathological processes related to metabolism, cancer, and aging. Their research outputs contribute to expanding understanding in fields that intersect basic sciences and clinical applications.

Best Publications

  • MassBank: a public repository for sharing mass spectral data for life sciences.

    Hisayuki Horai;Masanori Arita;Masanori Arita;Shigehiko Kanaya;Yoshito Nihei

  • Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer

    Shinichi Yachida;Sayaka Mizutani;Hirotsugu Shiroma;Satoshi Shiba

  • Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

    Akiyoshi Hirayama;Kenjiro Kami;Masahiro Sugimoto;Maki Sugawara

  • Quantitative Metabolome Analysis Using Capillary Electrophoresis Mass Spectrometry

    Tomoyoshi Soga;Yoshiaki Ohashi;Yuki Ueno;Hisako Naraoka

  • Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles

    Masahiro Sugimoto;David T W Wong;David T W Wong;Akiyoshi Hirayama;Tomoyoshi Soga

  • Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption.

    Tomoyoshi Soga;Richard Baran;Makoto Suematsu;Yuki Ueno

  • Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

    Keiyo Takubo;Go Nagamatsu;Chiharu I. Kobayashi;Ayako Nakamura-Ishizu

  • Multiple high-throughput analyses monitor the response of E. coli to perturbations.

    Nobuyoshi Ishii;Kenji Nakahigashi;Tomoya Baba;Tomoya Baba;Martin Robert

  • Amino acid analysis by capillary electrophoresis electrospray ionization mass spectrometry.

    Tomoyoshi Soga;David N. Heiger

  • Simultaneous determination of anionic intermediates for Bacillus subtilis metabolic pathways by capillary electrophoresis electrospray ionization mass spectrometry.

    Tomoyoshi Soga;Yuki Ueno;Hisako Naraoka;Yoshiaki Ohashi

  • UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis.

    Kenji Ikeda;Qianqian Kang;Takeshi Yoneshiro;Joao Paulo Camporez

  • Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

    Julie Adam;Emine Hatipoglu;Linda O'Flaherty;Nicola Ternette

  • Oncometabolites: linking altered metabolism with cancer

    Ming Yang;Tomoyoshi Soga;Patrick J. Pollard

  • BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.

    Takeshi Yoneshiro;Qiang Wang;Kazuki Tajima;Mami Matsushita

  • Autophagy protects the proximal tubule from degeneration and acute ischemic injury.

    Tomonori Kimura;Yoshitsugu Takabatake;Atsushi Takahashi;Jun Ya Kaimori

  • Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.

    Yoichi Imaizumi;Yohei Okada;Wado Akamatsu;Masato Koike

  • Metabolome analysis by capillary electrophoresis-mass spectrometry.

    Maria Rowena N. Monton;Tomoyoshi Soga

  • Metabolomic profiling of anionic metabolites by capillary electrophoresis mass spectrometry.

    Tomoyoshi Soga;Kaori Igarashi;Chiharu Ito;Katsuo Mizobuchi

  • Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC

    Kiyotoshi Satoh;Shinichi Yachida;Masahiro Sugimoto;Minoru Oshima

  • p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.

    Tetsuya Saito;Yoshinobu Ichimura;Yoshinobu Ichimura;Keiko Taguchi;Takafumi Suzuki

  • Analysis of Metabolic Remodeling in Compensated Left Ventricular Hypertrophy and Heart Failure

    Takao Kato;Shinichiro Niizuma;Yasutaka Inuzuka;Tsuneaki Kawashima

  • Bioinformatics Tools for Mass Spectroscopy-Based Metabolomic Data Processing and Analysis.

    Masahiro Sugimoto;Masato Kawakami;Martin Robert;Tomoyoshi Soga

Frequent Co-Authors

Masaru Tomita
Masaru Tomita Keio University
Makoto Suematsu
Makoto Suematsu Keio University
Takaaki Nishioka
Takaaki Nishioka Kyoto University
Takaaki Abe
Takaaki Abe Tohoku University
Tomoyoshi Nozaki
Tomoyoshi Nozaki University of Tokyo
Shinji Fukuda
Shinji Fukuda Kanagawa Institute of Technology
Shinya Kuroda
Shinya Kuroda University of Tokyo
Sadayoshi Ito
Sadayoshi Ito Tohoku University
Toru Kita
Toru Kita Kyoto University
Hirotada Mori
Hirotada Mori Nara Institute of Science and Technology

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