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Takaaki Abe

Takaaki Abe

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
17598
World Ranking
8152
National Ranking
546

Overview

Takaaki Abe is affiliated with Tohoku University in Japan and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans various subfields including Molecular Biology, Physiology, Nephrology, Rheumatology, and Epidemiology.

The scientist's main topics of study cover a range of biomedical and biochemical areas, such as:

  • Mitochondrial Function and Pathology
  • RNA modifications and cancer
  • Metabolism and Genetic Disorders
  • Gut microbiota and health
  • Diet and metabolism studies
  • Dialysis and Renal Disease Management
  • GDF15 and Related Biomarkers

Among recent publications, notable papers include:

  • "A non-canonical vitamin K cycle is a potent ferroptosis suppressor," 2022, published in Nature
  • "Uric Acid Elevation by Favipiravir, an Antiviral Drug," 2020, published in The Tohoku Journal of Experimental Medicine
  • "The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation," 2020, published in RNA Biology
  • "Isolation and initial structure-functional characterization of endogenous tRNA-derived stress-induced RNAs," 2020, published in RNA Biology
  • "Contribution of NRF2 to sulfur metabolism and mitochondrial activity," 2023, published in Redox Biology

Takaaki Abe frequently collaborates with several researchers in related fields. Regular coauthors include Takafumi Toyohara, Kôichi Kikuchi, Eikan Mishima, Chitose Suzuki, and Takehiro Suzuki. These collaborations reflect a sustained engagement with colleagues active in complementary biomedical research areas.

Publication venues where the scientist has contributed multiple works include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Society of Nephrology
  • International Journal of Molecular Sciences
  • Research Square
  • Scientific Reports

The body of work by Takaaki Abe integrates molecular biology with clinical and physiological dimensions, emphasizing the regulation of mitochondrial function, RNA biology, metabolic disorders, and renal disease management.

Best Publications

  • Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus.

    Ryuichi Shigemoto;Ayae Kinoshita;Eiki Wada;Sakashi Nomura

  • Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

    T Abe;H Sugihara;H Nawa;R Shigemoto

  • Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1.

    Takaaki Abe;Masayuki Kakyo;Taro Tokui;Rie Nakagomi

  • Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2.

    Takaaki Abe;Masayuki Kakyo;Hiroyuki Sakagami;Taro Tokui

  • Structure and regulation of rat long-chain acyl-CoA synthetase.

    H Suzuki;Y Kawarabayasi;J Kondo;T Abe

  • LST-2, A human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers

    Takaaki Abe;Michiaki Unno;Tohru Onogawa;Taro Tokui

  • Antibodies inactivating mGluR1 metabotropic glutamate receptor block long-term depression in cultured Purkinje cells

    Ryuichi Shigemoto;Takaaki Abe;Sakashi Nomura;Shigetada Nakanishi

  • Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney.

    Tsuyoshi Mikkaichi;Takehiro Suzuki;Tohru Onogawa;Tohru Onogawa;Masayuki Tanemoto

  • Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and multidrug resistance-associated protein 2 (MRP2/ABCC2)

    Makoto Sasaki;Hiroshi Suzuki;Kousei Ito;Takaaki Abe

  • Human Liver-Specific Organic Anion Transporter, LST-1, Mediates Uptake of Pravastatin by Human Hepatocytes

    Daisuke Nakai;Rie Nakagomi;Yoshitake Furuta;Taro Tokui

  • The organic anion transporter (OATP) family.

    Tsuyoshi Mikkaichi;Takehiro Suzuki;Masayuki Tanemoto;Sadayoshi Ito

  • Characterization of the Efflux Transport of 17β-Estradiol-d-17β-glucuronide from the Brain across the Blood-Brain Barrier

    Daisuke Sugiyama;Hiroyuki Kusuhara;Yoshihisa Shitara;Takaaki Abe

  • Nongenomic Vascular Action of Aldosterone in the Glomerular Microcirculation

    Shuji Arima;Kentaro Kohagura;Hong Lan Xu;Akira Sugawara

  • Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease

    Koichi Kikuchi;Daisuke Saigusa;Yoshitomi Kanemitsu;Yotaro Matsumoto

  • Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner.

    Koh Fujiwara;Hisanobu Adachi;Toshiyuki Nishio;Michiaki Unno

  • Simultaneous absolute quantification of 11 cytochrome P450 isoforms in human liver microsomes by liquid chromatography tandem mass spectrometry with in silico target peptide selection.

    Hirotaka Kawakami;Sumio Ohtsuki;Junichi Kamiie;Takashi Suzuki

  • Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS–based metabolomics approach

    Eikan Mishima;Shinji Fukuda;Chikahisa Mukawa;Akinori Yuri

  • Alteration of the Intestinal Environment by Lubiprostone Is Associated with Amelioration of Adenine-Induced CKD

    Eikan Mishima;Shinji Fukuda;Hisato Shima;Akiyoshi Hirayama

  • Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters

    Mitsunori Okabe;Gergely Szakács;Gergely Szakács;Mark A. Reimers;Mark A. Reimers;Toshihiro Suzuki;Toshihiro Suzuki

  • Characterization of the organic cation transporter SLC22A16: a doxorubicin importer.

    Mitsunori Okabe;Michiaki Unno;Hideo Harigae;Mitsuo Kaku

Frequent Co-Authors

Sadayoshi Ito
Sadayoshi Ito Tohoku University
Michiaki Unno
Michiaki Unno Tohoku University
Tomoyoshi Soga
Tomoyoshi Soga Keio University
Shigeo Kure
Shigeo Kure Tohoku University
Takashi Suzuki
Takashi Suzuki Tohoku University
Tetsuya Terasaki
Tetsuya Terasaki Tohoku University
Ken-ichiro Hayashi
Ken-ichiro Hayashi Okayama University of Science
Seiki Matsuno
Seiki Matsuno Tohoku University
Yuichi Sugiyama
Yuichi Sugiyama University of Tokyo
Hironobu Sasano
Hironobu Sasano Tohoku University

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