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Medicine

D-Index
70
Citations
14219
World Ranking
20130
National Ranking
24

Overview

Andrzej Pilc is affiliated with the Polish Academy of Sciences in Poland and has a research profile centered primarily in the field of neuroscience. Their work spans several interconnected disciplines including cellular and molecular neuroscience, biological psychiatry, pharmacology, molecular biology, and clinical psychology.

The main fields of study reflect a strong focus on neuroscience, with 26 publications, particularly addressing topics such as tryptophan and brain disorders, neuroscience and neuropharmacology research, and the treatment of major depression. Additional research interests encompass psychedelics and drug studies, receptor mechanisms and signaling, chemical synthesis and alkaloids, and the influence of neurotransmitter receptors on behavior.

Frequent publication venues for Andrzej Pilc include:

  • Pharmacological Reports
  • Nauka
  • Expert Opinion on Drug Discovery
  • Pharmacology Biochemistry and Behavior
  • Neuroscience Applied

Some of the recent papers associated with their research are:

  • "Efficacy of single and repeated administration of ketamine in unipolar and bipolar depression: a meta-analysis of randomized clinical trials" (2020, Pharmacological Reports)
  • "The Trace Kynurenine, Cinnabarinic Acid, Displays Potent Antipsychotic-Like Activity in Mice and Its Levels Are Reduced in the Prefrontal Cortex of Individuals Affected by Schizophrenia" (2020, Schizophrenia Bulletin)
  • "Glutamatergic dysregulation in mood disorders: opportunities for the discovery of novel drug targets" (2020, Expert Opinion on Therapeutic Targets)
  • "Where do we go next in antidepressant drug discovery? A new generation of antidepressants: a pivotal role of AMPA receptor potentiation and mGlu2/3 receptor antagonism" (2022, Expert Opinion on Drug Discovery)
  • "The Potential of Scopolamine as an Antidepressant in Major Depressive Disorder: A Systematic Review of Randomized Controlled Trials" (2023, Biomedicines)

Collaborations are a consistent part of their work, with frequent co-authors including Yana Babii, Paweł Kawalec, Piotr Brański, Agnieszka Pałucha-Poniewiera, and Tomasz Brzostek. These partnerships reflect a collaborative approach to research within their areas of expertise.

Best Publications

  • Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men

    J A Zoladz;A Pilc;J Majerczak;M Grandys

  • Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist.

    Ewa Tatarczyńska;Aleksandra Kłodzińska;Ewa Chojnacka-Wójcik;Agnieszka Pałucha

  • The effect of physical activity on the brain derived neurotrophic factor: from animal to human studies.

    J A Zoladz;A Pilc

  • Effect of zinc supplementation on antidepressant therapy in unipolar depression: a preliminary placebo-controlled study.

    Gabriel Nowak;Marcin Siwek;Dominika Dudek;Andrzej Zieba

  • Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs

    Agnieszka Palucha;Andrzej Pilc;Andrzej Pilc

  • Zinc supplementation augments efficacy of imipramine in treatment resistant patients: a double blind, placebo-controlled study.

    Marcin Siwek;Dominika Dudek;Ian A. Paul;Magdalena Sowa-Kućma

  • Mood disorders: regulation by metabotropic glutamate receptors.

    Andrzej Pilc;Shigeyuki Chaki;Gabriel Nowak;Jeffrey M. Witkin

  • Zinc and depression. An update.

    Gabriel Nowak;Bernadeta Szewczyk;Andrzej Pilc

  • Antidepressant-like effects of acute and chronic treatment with zinc in forced swim test and olfactory bulbectomy model in rats.

    Gabriel Nowak;Bernadeta Szewczyk;Joanna M. Wieronska;Piotr Branski

  • Antidepressant-like properties of zinc in rodent forced swim test.

    Bernadeta Kroczka;Piotr Branski;Agnieszka Palucha;Andrzej Pilc;Andrzej Pilc

  • Antidepressant activity of zinc and magnesium in view of the current hypotheses of antidepressant action.

    Bernadeta Szewczyk;Ewa Poleszak;Magdalena Sowa-Kućma;Marcin Siwek

  • Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats.

    A Pilc;A Kłodzińska;P Brański;G Nowak;G Nowak

  • Antidepressant- and anxiolytic-like activity of magnesium in mice.

    Ewa Poleszak;Bernadeta Szewczyk;Ewa Kędzierska;Piotr Wlaź

  • Enhancement of responsiveness of the central serotonergic system and serotonin-2 receptor density in rat frontal cortex by electroconvulsive treatment.

    Jerzy Vetulani;Urszula Lebrecht;Andrzej Pilc

  • Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats.

    A Pałucha;E Tatarczyńska;P Brański;B Szewczyk

  • LY354740, a group II metabotropic glutamate receptor agonist with potential antiparkinsonian properties in rats

    J. Konieczny;K. Ossowska;S. Wolfarth;A. Pilc

  • Blockade of the metabotropic glutamate receptor subtype 5 (mGluR5) produces antiparkinsonian-like effects in rats

    K Ossowska;J Konieczny;S Wolfarth;J Wierońska

  • Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist

    Agnieszka Pałucha;Piotr Brański;Bernadeta Szewczyk;Joanna M. Wierońska

  • Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.

    Agnieszka Palucha;Kinga Klak;Piotr Branski;Herman van der Putten

  • Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models.

    Aleksandra Kłodzińska;Ewa Chojnacka-Wójcik;Agnieszka Pałucha;Piotr Brański

Frequent Co-Authors

Gabriel Nowak
Gabriel Nowak Jagiellonian University
Jerzy Vetulani
Jerzy Vetulani Polish Academy of Sciences
Mariusz Papp
Mariusz Papp Polish Academy of Sciences
Piotr Popik
Piotr Popik Polish Academy of Sciences
Shigeyuki Chaki
Shigeyuki Chaki Taisho Pharmaceutical (Japan)
Brian Godman
Brian Godman University of Strathclyde
Władysław Lasoń
Władysław Lasoń Polish Academy of Sciences
Wolfgang Froestl
Wolfgang Froestl AC Immune (Switzerland)
Rainer Kuhn
Rainer Kuhn Novartis (Switzerland)
J. Van Staden
J. Van Staden University of KwaZulu-Natal

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