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Gerard Sanacora

Gerard Sanacora

D-Index & Metrics

Medicine

D-Index
92
Citations
37269
World Ranking
11169
National Ranking
5745

Overview

Gerard Sanacora is affiliated with Yale University in the United States and has an extensive body of research primarily focused on psychiatry, neuroscience, and the treatment of major depression. Their work spans multiple domains within medicine and neuroscience, with a particular emphasis on pharmacology and mental health.

Among the most notable recent papers authored or co-authored by Sanacora are:

  • Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation (2021, American Journal of Psychiatry)
  • Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions (2023, World Psychiatry)
  • Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions (2021, Nature Neuroscience)
  • Single-Dose Psilocybin Treatment for Major Depressive Disorder (2023, JAMA)
  • Esketamine Nasal Spray for Rapid Reduction of Major Depressive Disorder Symptoms in Patients Who Have Active Suicidal Ideation With Intent (2020, The Journal of Clinical Psychiatry)

Frequent co-authors collaborating with Sanacora include:

  • Samuel T. Wilkinson
  • James W. Murrough
  • Sanjay J. Mathew
  • Sina Nikayin
  • John H. Krystal

Sanacora publishes regularly across several prominent venues, notably:

  • JAMA Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Psychiatry
  • The Journal of Clinical Psychiatry
  • Biological Psychiatry

Their main fields of study include:

  • Medicine
  • Neuroscience

Within these fields, Sanacora focuses on several subfields such as:

  • Pharmacology
  • Experimental and Cognitive Psychology
  • Biological Psychiatry
  • Cellular and Molecular Neuroscience
  • Psychiatry and Mental Health

The core research topics addressed in their publications cover:

  • Treatment of Major Depression
  • Tryptophan and brain disorders
  • Mental Health Research Topics
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Neuroscience and Neuropharmacology Research
  • Electroconvulsive Therapy Studies
  • Stress Responses and Cortisol

Best Publications

  • Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

    Ronald S Duman;George K Aghajanian;Gerard Sanacora;John H Krystal

  • The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

    Maurizio Popoli;Zhen Yan;Bruce S. McEwen;Gerard Sanacora

  • Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications.

    Srijan Sen;Ronald Duman;Gerard Sanacora

  • Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders.

    Gerard Sanacora;Giulia Treccani;Maurizio Popoli

  • Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression.

    Gerard Sanacora;Ralitza Gueorguieva;C. Neill Epperson;Yu-Te Wu

  • Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

    Gerard Sanacora;Carlos A. Zarate;John H. Krystal;Husseini K. Manji

  • Altered connectivity in depression: GABA and glutamate neurotransmitter deficits and reversal by novel treatments

    Ronald S. Duman;Gerard Sanacora;John H. Krystal

  • Reduced Cortical γ-Aminobutyric Acid Levels in Depressed Patients Determined by Proton Magnetic Resonance Spectroscopy

    Gerard Sanacora;Graeme F. Mason;Douglas L. Rothman;Kevin L. Behar

  • Inhibition of hypothalamic neuropeptide Y gene expression by insulin

    Michael W. Schwartz;Alfred J. Sipols;Jonathan L. Marks;Gerard Sanacora

  • The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

    Samuel T. Wilkinson;Elizabeth D. Ballard;Michael H. Bloch;Sanjay J. Mathew

  • Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments

    J H Krystal;G Sanacora;H Blumberg;A Anand

  • Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl)tropane and single photon emission computed tomography

    Robert T Malison;Lawrence H Price;Robert Berman;Christopher H van Dyck

  • A Double-Blind, Randomized, Placebo-Controlled, Dose-Frequency Study of Intravenous Ketamine in Patients With Treatment-Resistant Depression

    Jaskaran B. Singh;Maggie Fedgchin;Ella J. Daly;Peter De Boer

  • Glial pathology in an animal model of depression: Reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole

    M Banasr;G M I Chowdhury;R Terwilliger;S S Newton

  • Increased cortical GABA concentrations in depressed patients receiving ECT.

    Gerard Sanacora;Graeme F. Mason;Douglas L. Rothman;Fahmeed Hyder

  • Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.

    Gerard Sanacora;Graeme F. Mason;Douglas L. Rothman;John H. Krystal

  • A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders.

    Gerard Sanacora;Mark A. Frye;William McDonald;Sanjay J. Mathew;Sanjay J. Mathew

  • Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study

    Carla M. Canuso;Jaskaran B. Singh;Maggie Fedgchin;Larry Alphs

  • A randomized clinical trial of repetitive transcranial magnetic stimulation in the treatment of major depression.

    Robert M Berman;Meera Narasimhan;Gerard Sanacora;Alexander P Miano

  • Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond.

    John H. Krystal;John H. Krystal;Gerard Sanacora;Ronald S. Duman;Ronald S. Duman

Frequent Co-Authors

John H. Krystal
John H. Krystal Yale University
Ronald S. Duman
Ronald S. Duman Yale University
Graeme F. Mason
Graeme F. Mason Yale University
Douglas L. Rothman
Douglas L. Rothman Yale University
Chadi G. Abdallah
Chadi G. Abdallah Baylor College of Medicine
Sanjay J. Mathew
Sanjay J. Mathew Baylor College of Medicine
Dennis S. Charney
Dennis S. Charney Icahn School of Medicine at Mount Sinai
Maurizio Fava
Maurizio Fava Harvard University
James W. Murrough
James W. Murrough Icahn School of Medicine at Mount Sinai
Kevin L. Behar
Kevin L. Behar Yale University

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