His main research concerns Internal medicine, Endocrinology, Glutamate receptor, Biochemistry and Glycogen. His work in Internal medicine tackles topics such as Diabetes mellitus which are related to areas like Offspring. His Endocrinology study incorporates themes from gamma-Aminobutyric acid, Neuroscience and Meal.
His Glutamate receptor study combines topics in areas such as Human brain, Glutamine, Citric acid cycle and Glutamic acid. His research in Human brain intersects with topics in Functional magnetic resonance spectroscopy of the brain and Nuclear magnetic resonance. His Biochemistry study integrates concerns from other disciplines, such as Cerebral cortex and Biophysics.
His primary areas of investigation include Internal medicine, Endocrinology, Nuclear magnetic resonance, Glutamate receptor and Neuroscience. His research is interdisciplinary, bridging the disciplines of Diabetes mellitus and Internal medicine. Endocrinology is a component of his Glycogen, Insulin, Glycogen synthase, Metabolism and Insulin resistance studies.
His Nuclear magnetic resonance research integrates issues from Magnetic resonance imaging and Human brain. His studies deal with areas such as Glutamine, Neurotransmission and Glutamic acid as well as Glutamate receptor. His study in Premovement neuronal activity, Neuroimaging, Functional magnetic resonance imaging, Resting state fMRI and Brain mapping are all subfields of Neuroscience.
Douglas L. Rothman spends much of his time researching Internal medicine, Endocrinology, Glutamate receptor, Neuroscience and Nuclear magnetic resonance. The study incorporates disciplines such as Type 2 diabetes and Human brain in addition to Internal medicine. Endocrinology is represented through his Metabolism, Insulin, Insulin resistance, Glycogen and Ketone bodies research.
While the research belongs to areas of Insulin resistance, Douglas L. Rothman spends his time largely on the problem of Somatostatin, intersecting his research to questions surrounding Glycogen synthase. His Glutamate receptor study combines topics from a wide range of disciplines, such as Astrocyte, Glutamine, Neurotransmission and Pharmacology. His work in Nuclear magnetic resonance addresses issues such as Magnetic resonance imaging, which are connected to fields such as Brain mapping.
Douglas L. Rothman mainly investigates Internal medicine, Glutamate receptor, Endocrinology, Biochemistry and Neuroscience. The various areas that he examines in his Internal medicine study include Occipital lobe and Magnetic resonance imaging. His Glutamate receptor research is multidisciplinary, relying on both Astrocyte, Anaerobic glycolysis, Glutamic acid, Antidepressant and Glutamine.
The concepts of his Glutamine study are interwoven with issues in Mitochondrion and Premovement neuronal activity. Many of his studies involve connections with topics such as Pyruvic acid and Endocrinology. His studies examine the connections between Biochemistry and genetics, as well as such issues in Biophysics, with regards to Chelation, Phosphonate, Extracellular and Nuclear magnetic resonance.
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Mitochondrial dysfunction in the elderly: possible role in insulin resistance
Kitt Falk Petersen;Douglas Befroy;Sylvie Dufour;James Dziura.
Science (2003)
Mechanism of free fatty acid-induced insulin resistance in humans.
Michael Roden;Thomas B. Price;Gianluca Perseghin;Kitt Falk Petersen.
Journal of Clinical Investigation (1996)
Effects of free fatty acids on glucose transport and IRS-1–associated phosphatidylinositol 3-kinase activity
Alan Dresner;Didier Laurent;Melissa Marcucci;Margaret E. Griffin.
Journal of Clinical Investigation (1999)
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.
Krssak M;Falk Petersen K;Dresner A;DiPietro L.
Diabetologia (1999)
Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by 13C Nuclear Magnetic Resonance Spectroscopy
Gerald I. Shulman;Douglas L. Rothman;Thomas Jue;Peter Stein.
The New England Journal of Medicine (1990)
Energy on Demand
Pierre J. Magistretti;Luc Pellerin;Douglas L. Rothman;Robert G. Shulman.
Science (1999)
Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression.
Gerard Sanacora;Ralitza Gueorguieva;C. Neill Epperson;Yu-Te Wu.
Archives of General Psychiatry (2004)
Increased Glucose Transport–Phosphorylation and Muscle Glycogen Synthesis after Exercise Training in Insulin-Resistant Subjects
Gianluca Perseghin;Thomas B. Price;Kitt Falk Petersen;Michael Roden.
The New England Journal of Medicine (1996)
Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity
Nicola R. Sibson;Ajay Dhankhar;Graeme F. Mason;Douglas L. Rothman.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study.
I Magnusson;D L Rothman;L D Katz;R G Shulman.
Journal of Clinical Investigation (1992)
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