D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 122 Citations 53,781 409 World Ranking 1954 National Ranking 1142

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Metabolism
  • Endocrinology

His main research concerns Internal medicine, Endocrinology, Glutamate receptor, Biochemistry and Glycogen. His work in Internal medicine tackles topics such as Diabetes mellitus which are related to areas like Offspring. His Endocrinology study incorporates themes from gamma-Aminobutyric acid, Neuroscience and Meal.

His Glutamate receptor study combines topics in areas such as Human brain, Glutamine, Citric acid cycle and Glutamic acid. His research in Human brain intersects with topics in Functional magnetic resonance spectroscopy of the brain and Nuclear magnetic resonance. His Biochemistry study integrates concerns from other disciplines, such as Cerebral cortex and Biophysics.

His most cited work include:

  • Mitochondrial dysfunction in the elderly: possible role in insulin resistance (1696 citations)
  • Mechanism of free fatty acid-induced insulin resistance in humans. (1266 citations)
  • Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. (1113 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Internal medicine, Endocrinology, Nuclear magnetic resonance, Glutamate receptor and Neuroscience. His research is interdisciplinary, bridging the disciplines of Diabetes mellitus and Internal medicine. Endocrinology is a component of his Glycogen, Insulin, Glycogen synthase, Metabolism and Insulin resistance studies.

His Nuclear magnetic resonance research integrates issues from Magnetic resonance imaging and Human brain. His studies deal with areas such as Glutamine, Neurotransmission and Glutamic acid as well as Glutamate receptor. His study in Premovement neuronal activity, Neuroimaging, Functional magnetic resonance imaging, Resting state fMRI and Brain mapping are all subfields of Neuroscience.

He most often published in these fields:

  • Internal medicine (37.53%)
  • Endocrinology (35.01%)
  • Nuclear magnetic resonance (26.32%)

What were the highlights of his more recent work (between 2013-2021)?

  • Internal medicine (37.53%)
  • Endocrinology (35.01%)
  • Glutamate receptor (20.82%)

In recent papers he was focusing on the following fields of study:

Douglas L. Rothman spends much of his time researching Internal medicine, Endocrinology, Glutamate receptor, Neuroscience and Nuclear magnetic resonance. The study incorporates disciplines such as Type 2 diabetes and Human brain in addition to Internal medicine. Endocrinology is represented through his Metabolism, Insulin, Insulin resistance, Glycogen and Ketone bodies research.

While the research belongs to areas of Insulin resistance, Douglas L. Rothman spends his time largely on the problem of Somatostatin, intersecting his research to questions surrounding Glycogen synthase. His Glutamate receptor study combines topics from a wide range of disciplines, such as Astrocyte, Glutamine, Neurotransmission and Pharmacology. His work in Nuclear magnetic resonance addresses issues such as Magnetic resonance imaging, which are connected to fields such as Brain mapping.

Between 2013 and 2021, his most popular works were:

  • Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis (138 citations)
  • Direct evidence for activity-dependent glucose phosphorylation in neurons with implications for the astrocyte-to-neuron lactate shuttle (113 citations)
  • Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects. (104 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Metabolism
  • Biochemistry

Douglas L. Rothman mainly investigates Internal medicine, Glutamate receptor, Endocrinology, Biochemistry and Neuroscience. The various areas that he examines in his Internal medicine study include Occipital lobe and Magnetic resonance imaging. His Glutamate receptor research is multidisciplinary, relying on both Astrocyte, Anaerobic glycolysis, Glutamic acid, Antidepressant and Glutamine.

The concepts of his Glutamine study are interwoven with issues in Mitochondrion and Premovement neuronal activity. Many of his studies involve connections with topics such as Pyruvic acid and Endocrinology. His studies examine the connections between Biochemistry and genetics, as well as such issues in Biophysics, with regards to Chelation, Phosphonate, Extracellular and Nuclear magnetic resonance.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

Kitt Falk Petersen;Douglas Befroy;Sylvie Dufour;James Dziura.
Science (2003)

2355 Citations

Mechanism of free fatty acid-induced insulin resistance in humans.

Michael Roden;Thomas B. Price;Gianluca Perseghin;Kitt Falk Petersen.
Journal of Clinical Investigation (1996)

1955 Citations

Effects of free fatty acids on glucose transport and IRS-1–associated phosphatidylinositol 3-kinase activity

Alan Dresner;Didier Laurent;Melissa Marcucci;Margaret E. Griffin.
Journal of Clinical Investigation (1999)

1620 Citations

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

Krssak M;Falk Petersen K;Dresner A;DiPietro L.
Diabetologia (1999)

1531 Citations

Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by 13C Nuclear Magnetic Resonance Spectroscopy

Gerald I. Shulman;Douglas L. Rothman;Thomas Jue;Peter Stein.
The New England Journal of Medicine (1990)

1505 Citations

Energy on Demand

Pierre J. Magistretti;Luc Pellerin;Douglas L. Rothman;Robert G. Shulman.
Science (1999)

1400 Citations

Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression.

Gerard Sanacora;Ralitza Gueorguieva;C. Neill Epperson;Yu-Te Wu.
Archives of General Psychiatry (2004)

1083 Citations

Increased Glucose Transport–Phosphorylation and Muscle Glycogen Synthesis after Exercise Training in Insulin-Resistant Subjects

Gianluca Perseghin;Thomas B. Price;Kitt Falk Petersen;Michael Roden.
The New England Journal of Medicine (1996)

913 Citations

Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

Nicola R. Sibson;Ajay Dhankhar;Graeme F. Mason;Douglas L. Rothman.
Proceedings of the National Academy of Sciences of the United States of America (1998)

908 Citations

Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study.

I Magnusson;D L Rothman;L D Katz;R G Shulman.
Journal of Clinical Investigation (1992)

862 Citations

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