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Douglas L. Rothman

Douglas L. Rothman

D-Index & Metrics

Medicine

D-Index
128
Citations
62314
World Ranking
2706
National Ranking
1512

Overview

Douglas L. Rothman is affiliated with Yale University in the United States. Their research contributions span multiple fields with a focus on medicine, neuroscience, and biochemistry, genetics, and molecular biology. They have notable work in subfields such as physiology, radiology, nuclear medicine and imaging, molecular biology, cellular and molecular neuroscience, and cognitive neuroscience.

The scientist's research topics cover advanced MRI techniques and applications, diet and metabolism studies, neuroscience and neuropharmacology research, mitochondrial function and pathology, functional brain connectivity studies, adipose tissue and metabolism, and advanced NMR techniques and applications.

Douglas L. Rothman has frequently published in venues including:

  • Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
  • Journal of Neurochemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Diabetes
  • NMR in Biomedicine

Recent publications by Douglas L. Rothman include:

  • Metabolic control analysis of hepatic glycogen synthesis in vivo, 2020, Proceedings of the National Academy of Sciences
  • Brain energy metabolism: A roadmap for future research, 2024, Journal of Neurochemistry
  • Reevaluation of Astrocyte-Neuron Energy Metabolism with Astrocyte Volume Fraction Correction: Impact on Cellular Glucose Oxidation Rates, Glutamate-Glutamine Cycle Energetics, Glycogen Levels and Utilization Rates vs. Exercising Muscle, and Na+/K+ Pumping Rates, 2020, Neurochemical Research
  • Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference, 2020, Cell Metabolism
  • Metabolic underpinnings of activated and deactivated cortical areas in human brain, 2021, Journal of Cerebral Blood Flow & Metabolism

Frequent co-authors collaborating with Douglas L. Rothman include:

  • Graeme F. Mason
  • Gerald A. Dienel
  • Kevin L. Behar
  • Silvia Mangia
  • Janice J. Hwang

Best Publications

  • Mitochondrial dysfunction in the elderly: possible role in insulin resistance

    Kitt Falk Petersen;Douglas Befroy;Sylvie Dufour;James Dziura

  • Mechanism of free fatty acid-induced insulin resistance in humans.

    Michael Roden;Thomas B. Price;Gianluca Perseghin;Kitt Falk Petersen

  • Effects of free fatty acids on glucose transport and IRS-1–associated phosphatidylinositol 3-kinase activity

    Alan Dresner;Didier Laurent;Melissa Marcucci;Margaret E. Griffin

  • Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

    Krssak M;Falk Petersen K;Dresner A;DiPietro L

  • Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by 13C Nuclear Magnetic Resonance Spectroscopy

    Gerald I. Shulman;Douglas L. Rothman;Thomas Jue;Peter Stein

  • Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression.

    Gerard Sanacora;Ralitza Gueorguieva;C. Neill Epperson;Yu-Te Wu

  • Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

    Nicola R. Sibson;Ajay Dhankhar;Graeme F. Mason;Douglas L. Rothman

  • Increased Glucose Transport–Phosphorylation and Muscle Glycogen Synthesis after Exercise Training in Insulin-Resistant Subjects

    Gianluca Perseghin;Thomas B. Price;Kitt Falk Petersen;Michael Roden

  • Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study.

    I Magnusson;D L Rothman;L D Katz;R G Shulman

  • Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes.

    Gary W. Cline;Kitt Falk Petersen;Martin Krssak;Jun Shen

  • The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome

    Kitt Falk Petersen;Sylvie Dufour;David B. Savage;Stefan Bilz

  • Reduced Cortical γ-Aminobutyric Acid Levels in Depressed Patients Determined by Proton Magnetic Resonance Spectroscopy

    Gerard Sanacora;Graeme F. Mason;Douglas L. Rothman;Kevin L. Behar

  • Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation.

    James Prichard;Douglas Rothman;Edward Novotny;Ognen Petroff

  • Energetic basis of brain activity: implications for neuroimaging

    Robert G Shulman;Douglas L Rothman;Kevin L Behar;Fahmeed Hyder

  • Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity.

    Ranjana Sinha;Sylvie Dufour;Kitt Falk Petersen;Vincent LeBon

  • Quantitation of hepatic glycogenolysis and gluconeogenesis in fasting humans with 13C NMR

    Douglas L. Rothman;Inger Magnusson;Lee D. Katz;Robert G. Shulman

  • Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo.

    Douglas L. Rothman;Ognen A. C. Petroff;Kevin L. Behar;Richard H. Mattson

  • Analysis of macromolecule resonances in 1H NMR spectra of human brain.

    Kevin L. Behar;Douglas L. Rothman;Dennis D. Spencer;Ognen A. C. Petroff

  • Increased cortical GABA concentrations in depressed patients receiving ECT.

    Gerard Sanacora;Graeme F. Mason;Douglas L. Rothman;Fahmeed Hyder

  • Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors.

    Gerard Sanacora;Graeme F. Mason;Douglas L. Rothman;John H. Krystal

Frequent Co-Authors

Kevin L. Behar
Kevin L. Behar Yale University
Robert G. Shulman
Robert G. Shulman Yale University
Fahmeed Hyder
Fahmeed Hyder Yale University
Graeme F. Mason
Graeme F. Mason Yale University
Gerald I. Shulman
Gerald I. Shulman Yale University
Ognen A. C. Petroff
Ognen A. C. Petroff Yale University
Kitt Falk Petersen
Kitt Falk Petersen Yale University
Gary W. Cline
Gary W. Cline Yale University
John H. Krystal
John H. Krystal Yale University
Gerard Sanacora
Gerard Sanacora Yale University

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