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Best Scientists

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194
Citations
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Medicine

D-Index
194
Citations
208604
World Ranking
221
National Ranking
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Research.com Recognitions

  • 2025 - Research.com Best Scientists Award
  • 2023 - Research.com Medicine in United States Leader Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Ralph A. DeFronzo is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research primarily focuses on the field of Medicine, with a significant concentration on Endocrinology, Diabetes, and Metabolism. Their work spans several subfields including Surgery, Molecular Biology, Physiology, and Cardiology and Cardiovascular Medicine.

The scientist's main topics of work cover a variety of areas related to diabetes and metabolism. These include:

  • Diabetes Treatment and Management
  • Pancreatic function and diabetes
  • Metabolism, Diabetes, and Cancer
  • Diabetes Management and Research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Diet and metabolism studies
  • Liver Disease Diagnosis and Treatment

Frequent publication venues highlight where the scientist's research contributions have appeared regularly. These venues include:

  • Diabetes Obesity and Metabolism
  • The Journal of Clinical Endocrinology & Metabolism
  • Diabetes Care
  • Endocrine Practice
  • bioRxiv (Cold Spring Harbor Laboratory)

Collaboration has been a notable feature of their research, with several frequent co-authors. Notable collaborators include:

  • Muhammad Abdul-Ghani
  • Curtis Triplitt
  • John M. Adams
  • Yehuda Handelsman
  • John Blangero

Among recent scholarly papers attributed to this scientist are:

  • Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Comprehensive Type 2 Diabetes Management Algorithm - 2020 Executive Summary (2020, Endocrine Practice)
  • American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update (2022, Endocrine Practice)
  • Insulin: The master regulator of glucose metabolism (2022, Metabolism)
  • Early intervention and intensive management of patients with diabetes, cardiorenal, and metabolic diseases (2023, Journal of Diabetes and its Complications)
  • Therapeutic Manipulation of Myocardial Metabolism (2021, Journal of the American College of Cardiology)

Ralph A. DeFronzo has also been recognized as a Member of the Association of American Physicians.

Best Publications

  • Report of the expert committee on the diagnosis and classification of diabetes mellitus

    James R. Gavin;K. G M M Alberti;Mayer B. Davidson;Ralph A. DeFronzo

  • Glucose clamp technique: a method for quantifying insulin secretion and resistance.

    Ralph A. Defronzo;Jordan D. Tobin;Reubin Andres

  • Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease

    Ralph A. DeFronzo;Eleuterio Ferrannini

  • Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

    Masafumi Matsuda;Ralph A. DeFronzo

  • Insulin Sensitivity Indices Obtained from Oral Glucose Tolerance Test: Comparison with the Euglycemic Insulin Clamp

    Masafumi Matsuda;Ralph A. Defronzo

  • Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

    Ralph A DeFronzo

  • From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

    Ralph A. DeFronzo

  • Follow-up report on the diagnosis of diabetes mellitus.

    Saul Genuth;K. G M M Alberti;Peter Bennett;John Buse

  • International Expert Committee Report on the Role of the A1C Assay in the Diagnosis of Diabetes

    David M. Nathan;Beverly Balkau;Enzo Bonora;Knut Borch-Johnsen

  • Pathogenesis of NIDDM: A balanced overview

    Ralph A DeFronzo;Riccardd C Bonadonna;Eleuterio Ferrannini

  • Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

    Mary Elizabeth Patti;Atul J. Butte;Sarah Crunkhorn;Kenneth Cusi

  • The Effect of Insulin on the Disposal of Intravenous Glucose: Results from Indirect Calorimetry and Hepatic and Femoral Venous Catheterization

    R. A. DeFronzo;E. Jacot;E. Jequier;E. Maeder

  • A Placebo-Controlled Trial of Pioglitazone in Subjects with Nonalcoholic Steatohepatitis

    Renata Belfort;Stephen A. Harrison;Kenneth Brown;Celia Darland

  • Effects of Exenatide (Exendin-4) on Glycemic Control and Weight Over 30 Weeks in Metformin-Treated Patients With Type 2 Diabetes

    Ralph A. DeFronzo;Robert E. Ratner;Jenny Han;Dennis D. Kim

  • Skeletal Muscle Insulin Resistance Is the Primary Defect in Type 2 Diabetes

    Ralph A. DeFronzo;Devjit Tripathy

  • Impaired fasting glucose and impaired glucose tolerance: implications for care.

    David M. Nathan;Mayer B. Davidson;Ralph A. DeFronzo;Robert J. Heine

  • Type 2 diabetes mellitus.

    Ralph A. DeFronzo;Ele Ferrannini;Leif Groop;Robert R. Henry

  • Pharmacologic Therapy for Type 2 Diabetes Mellitus

    Ralph A. DeFronzo

  • Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus

    Ralph A. DeFronzo;Anita M. Goodman

  • Pathogenesis of type 2 diabetes mellitus

    Ralph A DeFronzo

Frequent Co-Authors

Amalia Gastaldelli
Amalia Gastaldelli National Research Council (CNR)
Lawrence J. Mandarino
Lawrence J. Mandarino University of Arizona
Leif Groop
Leif Groop Lund University
John Blangero
John Blangero The University of Texas Rio Grande Valley
Ravindranath Duggirala
Ravindranath Duggirala Texas A&M University – San Antonio
Kenneth Cusi
Kenneth Cusi University of Florida
Franco Folli
Franco Folli University of Milan
Philip Felig
Philip Felig Yale University
Jason Flannick
Jason Flannick Broad Institute
John C. Chambers
John C. Chambers Guy's and St Thomas' NHS Foundation Trust

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