What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His primary scientific interests are in Internal medicine, Endocrinology, Insulin, Insulin resistance and Type 2 diabetes.
As part of his studies on Internal medicine, Lawrence J. Mandarino often connects relevant areas like Diabetes mellitus.
His studies deal with areas such as Receptor and Pioglitazone as well as Insulin.
Lawrence J. Mandarino has included themes like Adipose tissue, Stimulation, Mitochondrion and Type 2 Diabetes Mellitus in his Insulin resistance study.
His research in Type 2 diabetes intersects with topics in Glucose tolerance test and Lipotoxicity.
His Skeletal muscle research integrates issues from Lipid metabolism, Biochemistry, Protein degradation, Connective tissue and Myocyte.
His most cited work include:
- Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 (1650 citations)
- Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle. (941 citations)
- Fuel selection in human skeletal muscle in insulin resistance: a reexamination. (796 citations)
What are the main themes of his work throughout his whole career to date?
Lawrence J. Mandarino mainly focuses on Internal medicine, Endocrinology, Insulin, Insulin resistance and Skeletal muscle.
His Internal medicine research incorporates elements of Diabetes mellitus and Type 2 diabetes.
His study in Insulin receptor, Carbohydrate metabolism, Glucose uptake, Glucose clamp technique and Glycogen synthase falls under the purview of Endocrinology.
His Insulin study frequently intersects with other fields, such as Physical exercise.
Lawrence J. Mandarino interconnects Whole blood, Adipose tissue, Adipocyte, Glycogenesis and Type 2 Diabetes Mellitus in the investigation of issues within Insulin resistance.
His Skeletal muscle research includes themes of Gene expression, Protein metabolism, Proteomics, Human obesity and Mitochondrion.
He most often published in these fields:
- Internal medicine (85.53%)
- Endocrinology (84.26%)
- Insulin (48.94%)
What were the highlights of his more recent work (between 2016-2021)?
- Internal medicine (85.53%)
- Endocrinology (84.26%)
- Skeletal muscle (39.57%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Internal medicine, Endocrinology, Skeletal muscle, Gene and Insulin resistance.
His Internal medicine study frequently links to adjacent areas such as Cardiology.
Within one scientific family, Lawrence J. Mandarino focuses on topics pertaining to Epigenetics under Endocrinology, and may sometimes address concerns connected to Methylation and Reduced representation bisulfite sequencing.
The various areas that Lawrence J. Mandarino examines in his Skeletal muscle study include Amino acid, Myocyte, Biophysics and Gene expression.
He is investigating Insulin resistance as part of his Diabetes mellitus and Insulin and Insulin resistance study.
His work deals with themes such as Alpha, Bioinformatics, Peroxisome proliferator-activated receptor, Myogenesis and Type 2 Diabetes Mellitus, which intersect with Insulin.
Between 2016 and 2021, his most popular works were:
- Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. (88 citations)
- Hemolysis-induced Lung Vascular Leakage Contributes to the Development of Pulmonary Hypertension. (21 citations)
- Characterization of the CLASP2 Protein Interaction Network Identifies SOGA1 as a Microtubule-Associated Protein (20 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Internal medicine
Lawrence J. Mandarino focuses on Internal medicine, Endocrinology, Obesity, Skeletal muscle and Molecular biology.
His research on Internal medicine often connects related areas such as Type 2 diabetes.
His Endocrinology study combines topics from a wide range of disciplines, such as DNA methylation, Reduced representation bisulfite sequencing, Inflammation, Pulmonary hypertension and Epigenetics.
Lawrence J. Mandarino has researched Obesity in several fields, including Genetics, Biobank, Gene, Genome-wide association study and Leucine.
His Skeletal muscle research is multidisciplinary, incorporating perspectives in Amino acid, Protein metabolism, Downregulation and upregulation, Protein biosynthesis and Phosphorylation.
The study of Diabetes mellitus and Insulin are components of his Insulin resistance research.
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