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D-Index & Metrics

Medicine

D-Index
98
Citations
52561
World Ranking
8756
National Ranking
4515

Overview

David E. Kelley is affiliated with the University of Pittsburgh in the United States. Their research primarily centers on the field of Medicine, with a focus on several subfields including Endocrinology, Diabetes and Metabolism, Surgery, Molecular Biology, Economics and Econometrics, and Cardiology and Cardiovascular Medicine.

Their recent scholarly output includes the following papers:

  • Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists, 2022, Nature Communications
  • Discovery of Insulin Receptor Partial Agonists MK-5160 and MK-1092 as Novel Basal Insulins with Potential to Improve Therapeutic Index, 2022, Journal of Medicinal Chemistry
  • A Practitioner's Guide and MATLAB Toolbox for Mixed Frequency State Space Models, 2020, SSRN Electronic Journal
  • Muscle insulin resistance in type 1 diabetes with coronary artery disease, 2020, Diabetologia
  • A Practitioner's Guide and MATLAB Toolbox for Mixed Frequency State Space Models, 2022, Journal of Statistical Software

The frequent co-authors working with David E. Kelley include:

  • Ester Carballo-Jane
  • Peter Zafian
  • Terri Kelly
  • Judith N. Gorski
  • Dmitri Pissarnitski

The scientist's publications appear regularly in several venues, notably:

  • Nature Communications
  • Journal of Medicinal Chemistry
  • Diabetologia
  • Journal of Statistical Software
  • SSRN Electronic Journal

The main topics covered by David E. Kelley's research include:

  • Pancreatic function and diabetes
  • Diabetes Treatment and Management
  • Italy: Economic History and Contemporary Issues
  • Metabolism, Diabetes, and Cancer
  • Receptor Mechanisms and Signaling
  • Cardiovascular Function and Risk Factors
  • Adipose Tissue and Metabolism

This profile reflects a research trajectory involving a combination of clinical and molecular approaches to metabolic diseases, especially diabetes, with overlapping interests in related cardiovascular and metabolic functions. The integration of economic and econometric elements suggests a multidisciplinary dimension in their work.

Best Publications

  • Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes

    David E. Kelley;Jing He;Elizabeth V. Menshikova;Vladimir B. Ritov

  • Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus.

    Philip R Schauer;Bartolome Burguera;Sayeed Ikramuddin;Dan Cottam

  • Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study.

    Bret H. Goodpaster;Catherine L. Carlson;Marjolein Visser;Marjolein Visser;David E. Kelley

  • Waist Circumference and Cardiometabolic Risk: A Consensus Statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, The Obesity Society; the American Society for Nutrition; and the American Diabetes Association

    Samuel Klein;David B. Allison;Steven B. Heymsfield;David E. Kelley

  • Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss.

    David E. Kelley;Bret Goodpaster;Rena R. Wing;Jean-Aime Simoneau

  • Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes: One-Year Results of the Look AHEAD Trial

    Mark Espeland;Xavier Pi-Sunyer;George Blackburn;Frederick L. Brancati

  • Subcutaneous Abdominal Fat and Thigh Muscle Composition Predict Insulin Sensitivity Independently of Visceral Fat

    Goodpaster Bh;Thaete Fl;Simoneau Ja;Kelley De

  • Skeletal Muscle Lipid Content and Insulin Resistance: Evidence for a Paradox in Endurance-Trained Athletes

    Bret H. Goodpaster;Jing He;Simon Watkins;David E. Kelley

  • Fuel selection in human skeletal muscle in insulin resistance: a reexamination.

    David E. Kelley;Lawrence J. Mandarino

  • Deficiency of Subsarcolemmal Mitochondria in Obesity and Type 2 Diabetes

    Vladimir B. Ritov;Elizabeth V. Menshikova;Jing He;Robert E. Ferrell

  • The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it.

    Thomas A Wadden;Delia Smith West;Linda Delahanty

  • Role of Orlistat in the Treatment of Obese Patients With Type 2 Diabetes: A 1-year randomized double-blind study

    Priscilla A Hollander;Steven C Elbein;Irl B Hirsch;David Kelley

  • Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content

    B. H. Goodpaster;D. E. Kelley;F. L. Thaete;Jing He

  • Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus.

    Goodpaster Bh;Thaete Fl;Kelley De

  • Effects of weight loss on regional fat distribution and insulin sensitivity in obesity.

    B H Goodpaster;D E Kelley;R R Wing;A Meier

  • Role of Reduced Suppression of Glucose Production and Diminished Early Insulin Release in Impaired Glucose Tolerance

    Asimina Mitrakou;David Kelley;Marian Mokan;Thiemo Veneman

  • The acute versus the chronic response to exercise.

    Paul D. Thompson;Stephen F. Crouse;Brett Goodpaster;David Kelley

  • Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance

    D E Kelley;F L Thaete;F Troost;T Huwe

  • Increased levels of plasma acylcarnitines in obesity and type 2 diabetes and identification of a marker of glucolipotoxicity.

    Stephanie J. Mihalik;Bret H. Goodpaster;David E. Kelley;Donald H. Chace

  • Waist circumference and cardiometabolic risk: a consensus statement from Shaping America's Health: Association for Weight Management and Obesity Prevention; NAASO, The Obesity Society; the American Society for Nutrition; and the American Diabetes

    Samuel Klein;David B Allison;Steven B Heymsfield;David E Kelley

Frequent Co-Authors

Bret H. Goodpaster
Bret H. Goodpaster Translational Research Institute
Julie C. Price
Julie C. Price Harvard University
Lewis H. Kuller
Lewis H. Kuller University of Pittsburgh
John M. Jakicic
John M. Jakicic University of Pittsburgh
Claudio Cobelli
Claudio Cobelli University of Padua
James O. Hill
James O. Hill University of Alabama at Birmingham
George A. Bray
George A. Bray Louisiana State University
Billy W. Day
Billy W. Day University of Pittsburgh
F. Xavier Pi-Sunyer
F. Xavier Pi-Sunyer Columbia University
Rena R. Wing
Rena R. Wing Brown University

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