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Matthijs K. C. Hesselink

Matthijs K. C. Hesselink

D-Index & Metrics

Medicine

D-Index
84
Citations
21207
World Ranking
15290
National Ranking
584

Matthijs K. C. Hesselink publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Matthijs K. C. Hesselink sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 250 publications — 8th percentile

8% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Matthijs K. C. Hesselink D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Matthijs K. C. Hesselink sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 84 D-Index — 27th percentile

27% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Matthijs K. C. Hesselink is affiliated with Maastricht University in the Netherlands and has contributed extensively to the fields of medicine, biochemistry, genetics, and molecular biology. Their research spans several subfields, notably physiology, molecular biology, cell biology, biochemistry, and endocrine and autonomic systems. The primary focus of their scientific work involves various aspects of metabolism and molecular mechanisms related to metabolic health.

Their main research topics include:

  • Adipose Tissue and Metabolism
  • Diet and metabolism studies
  • Muscle metabolism and nutrition
  • Mitochondrial Function and Pathology
  • Lipid metabolism and biosynthesis
  • Circadian rhythm and melatonin
  • Metabolism and Genetic Disorders

Matthijs K. C. Hesselink has published numerous papers, some of the notable recent works being:

  • Exercise training elicits superior metabolic effects when performed in the afternoon compared to morning in metabolically compromised humans, 2020, Physiological Reports
  • Timing of physical activity in relation to liver fat content and insulin resistance, 2022, Diabetologia
  • A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes, 2022, Nature Communications
  • Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity, 2020, Diabetologia
  • Resveratrol supplementation reduces ACE2 expression in human adipose tissue, 2021, Adipocyte

Their frequent co-authors include Patrick Schrauwen, Joris Hoeks, Vera B. Schrauwen-Hinderling, Gert Schaart, and Anne Gemmink, with whom they have collaborated on multiple research projects.

Matthijs K. C. Hesselink's work is regularly published in scientific journals such as Diabetologia, Physiological Reports, Nature Communications, Molecular Metabolism, and Obesity.

Best Publications

  • Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

    Silvie Timmers;Ellen Konings;Lena Bilet;Riekelt H. Houtkooper

  • ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

    Guenter Haemmerle;Tarek Moustafa;Gerald Woelkart;Sabrina Büttner

  • Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus

    Mark J W Hanssen;Joris Hoeks;Boudewijn Brans;Anouk A J J van der Lans

  • A new approach for the determination of ventilatory and lactate thresholds.

    B. Cheng;H. Kuipers;A. C. Snyder;H. A. Keizer

  • Optimisation of oil red O staining permits combination with immunofluorescence and automated quantification of lipids

    René Koopman;Gert Schaart;Matthijs K. Hesselink

  • Oxidative Capacity, Lipotoxicity, and Mitochondrial Damage in Type 2 Diabetes

    Patrick Schrauwen;Matthijs K.C. Hesselink

  • Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy.

    Estelle Woldt;Yasmine Sebti;Laura A Solt;Christian Duhem

  • Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

    Ruth C.R. Meex;Vera B. Schrauwen-Hinderling;Esther Moonen-Kornips;Gert Schaart

  • Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

    Esther Phielix;Vera B. Schrauwen-Hinderling;Marco Mensink;Ellen Lenaers

  • Intramyocellular lipid content in human skeletal muscle

    Vera B. Schrauwen-Hinderling;Matthijs K.C. Hesselink;Patrick Schrauwen;Marianne Eline Kooi

  • Physiological changes in male competitive cyclists after two weeks of intensified training.

    A. E. Jeukendrup;M. K. C. Hesselink;A. C. Snyder;H. Kuipers

  • Decreased Uncoupling Protein Expression and Intramyocytic Triglyceride Depletion in Formerly Obese Subjects

    Geltrude Mingrone;Giuseppina Rosa;Aldo V. Greco;Melania Manco

  • UCP2 and UCP3 in muscle controlling body metabolism.

    Patrick Schrauwen;Matthijs Hesselink

  • Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

    Matthijs K. C. Hesselink;Vera Schrauwen-Hinderling;Patrick Schrauwen

  • Mitochondrial dysfunction and lipotoxicity.

    Patrick Schrauwen;Vera Schrauwen-Hinderling;Joris Hoeks;Matthijs K.C. Hesselink

  • An alternative function for human uncoupling protein 3: protection of mitochondria against accumulation of nonesterified fatty acids inside the mitochondrial matrix

    Patrick Schrauwen;Wim H. M. Saris;Matthijs K C. Hesselink

  • Caloric Restriction and Exercise Increase Plasma ANGPTL4 Levels in Humans via Elevated Free Fatty Acids

    Sander Kersten;Laeticia Lichtenstein;Emma Steenbergen;Karin Mudde

  • Regulation of metabolic transcriptional co-activators and transcription factors with acute exercise

    Aaron P. Russell;Matthijs K. C. Hesselink;Sing Kai Lo;Patrick Schrauwen

  • Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1alpha and PPARbeta/delta gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus

    M. Mensink;M.K. Hesselink;A.P. Russell;G. Schaart

  • Effect of training in the fasted state on metabolic responses during exercise with carbohydrate intake.

    K. De Bock;W. Derave;B. O. Eijnde;M. K. Hesselink

Frequent Co-Authors

Patrick Schrauwen
Patrick Schrauwen Maastricht University
Sander Kersten
Sander Kersten Wageningen University & Research
Wim H. M. Saris
Wim H. M. Saris Maastricht University
Jan F. C. Glatz
Jan F. C. Glatz Maastricht University
Bart Staels
Bart Staels University of Lille
Ellen E. Blaak
Ellen E. Blaak Maastricht University
Anton J. M. Wagenmakers
Anton J. M. Wagenmakers Liverpool John Moores University
Hildo J. Lamb
Hildo J. Lamb Leiden University Medical Center
Michael Roden
Michael Roden Heinrich Heine University Düsseldorf
Asker E. Jeukendrup
Asker E. Jeukendrup Loughborough University

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