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Best Scientists
2025
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Medicine
France
2026

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Best Scientists

D-Index
192
Citations
135708
World Ranking
389
National Ranking
6

Medicine

D-Index
195
Citations
140992
World Ranking
216
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Medicine in France Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in France Leader Award
  • 2023 - Research.com Medicine in France Leader Award
  • 2022 - Research.com Medicine in France Leader Award

Overview

Bart Staels is affiliated with the University of Lille in France. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on subfields including Molecular Biology, Epidemiology, Physiology, Cardiology and Cardiovascular Medicine, and Surgery.

The main topics covered in Staels's work include:

  • Liver Disease Diagnosis and Treatment
  • Peroxisome Proliferator-Activated Receptors
  • Diet and Metabolism Studies
  • Adipose Tissue and Metabolism
  • Diet, Metabolism, and Disease
  • Circadian Rhythm and Melatonin
  • Drug Transport and Resistance Mechanisms

Staels has published extensively in several scientific venues. The most frequent publication venues include:

  • Journal of Hepatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Atherosclerosis
  • Molecular Metabolism
  • JHEP Reports

Among Staels's recent papers are the following:

  • "PPAR control of metabolism and cardiovascular functions," 2021, Nature Reviews Cardiology
  • "Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society," 2021, European Heart Journal
  • "Dysregulated lipid metabolism links NAFLD to cardiovascular disease," 2020, Molecular Metabolism
  • "A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study," 2020, The Lancet. Gastroenterology & Hepatology
  • "Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis," 2021, Nature Metabolism

Frequent co-authors collaborating with Staels include:

  • Philippe Lefèbvre
  • Anne Tailleux
  • David Dombrowicz
  • Nathalie Hennuyer
  • Jérôme Eeckhoute

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism

    Bart Staels;Jean Dallongeville;Johan Auwerx;Kristina Schoonjans

  • Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation

    Philippe Lefebvre;Bertrand Cariou;Fleur Lien;Folkert Kuipers

  • The organization, promoter analysis, and expression of the human PPARgamma gene.

    Lluis Fajas;Didier Auboeuf;Eric Raspé;Kristina Schoonjans

  • Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression.

    Kristina Schoonjans;Bart Staels;Johan Auwerx

  • PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties.

    M. Amine Bouhlel;M. Amine Bouhlel;M. Amine Bouhlel;Bruno Derudas;Bruno Derudas;Bruno Derudas;Elena Rigamonti;Elena Rigamonti;Elena Rigamonti;Rébecca Dièvart;Rébecca Dièvart;Rébecca Dièvart

  • PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene

    K. Schoonjans;J. Peinado-Onsurbe;A. M. Lefebvre;R. A. Heyman

  • Transient increase in obese gene expression after food intake or insulin administration.

    R Saladin;P De Vos;M Guerre-Millo;A Leturque

  • Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators

    Bart Staels;Wolfgang Koenig;Aïda Habib;Régine Merval

  • PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway.

    Chinetti G;Lestavel S;Bocher;Remaley At

  • The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation

    Kristina Schoonjans;Bart Staels;Johan Auwerx

  • Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

    Philippe Delerive;Karolien De Bosscher;Sandrine Besnard;Wim Vanden Berghe

  • Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease.

    Michal Pawlak;Philippe Lefebvre;Bart Staels

  • Protective role of interleukin-10 in atherosclerosis

    Ziad Mallat;Sandrine Besnard;Micheline Duriez;Virginie Deleuze

  • International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors

    Liliane Michalik;Johan Auwerx;Joel P. Berger;V. Krishna Chatterjee

  • Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages.

    Giulia Chinetti;Sabine Griglio;Micheline Antonucci;Inés Pineda Torra

  • Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation.

    G. Chinetti;J.-C. Fruchart;B. Staels

  • Sorting out the roles of PPARα in energy metabolism and vascular homeostasis

    Philippe Lefebvre;Giulia Chinetti;Jean-Charles Fruchart;Bart Staels

  • Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening

    Vlad Ratziu;Vlad Ratziu;Stephen A. Harrison;Sven Francque;Pierre Bedossa

  • Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients

    D Auboeuf;J Rieusset;L Fajas;P Vallier

Frequent Co-Authors

Jean-Charles Fruchart
Jean-Charles Fruchart Institut Pasteur
Johan Auwerx
Johan Auwerx École Polytechnique Fédérale de Lausanne
Catherine Fievet
Catherine Fievet Institut Pasteur
Folkert Kuipers
Folkert Kuipers University Medical Center Groningen
François Pattou
François Pattou University of Lille
Bertrand Cariou
Bertrand Cariou University of Nantes
Kristina Schoonjans
Kristina Schoonjans École Polytechnique Fédérale de Lausanne
Gérard Torpier
Gérard Torpier Institut Pasteur
Sven Francque
Sven Francque University of Antwerp

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