D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 57 Citations 14,320 156 World Ranking 2566 National Ranking 70

Overview

What is he best known for?

The fields of study he is best known for:

  • Neuroscience
  • Neuron
  • Gene

The scientist’s investigation covers issues in Neuroscience, Neocortex, Microscopy, Microscope and Anatomy. Neuroscience connects with themes related to Neurite in his study. His Neocortex research is multidisciplinary, incorporating perspectives in Preclinical imaging, Somatosensory system, Barrel cortex, Dendrite and Calcium imaging.

In his work, Fluorescence-lifetime imaging microscopy, Optical fiber and Image processing is strongly intertwined with Two-photon excitation microscopy, which is a subfield of Microscopy. His research investigates the connection with Microscope and areas like Laser which intersect with concerns in Biomedical engineering and Functional imaging. His Anatomy research integrates issues from Biophysics and Central nervous system, Neuroglia, Blood–brain barrier.

His most cited work include:

  • Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo (3556 citations)
  • Deep tissue two-photon microscopy (2857 citations)
  • Fluctuations and stimulus−induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex (654 citations)

What are the main themes of his work throughout his whole career to date?

Fritjof Helmchen mostly deals with Neuroscience, Neocortex, Calcium imaging, Two-photon excitation microscopy and Sensory system. His study involves Stimulus, Barrel cortex, Premovement neuronal activity, Somatosensory system and Biological neural network, a branch of Neuroscience. The concepts of his Neocortex study are interwoven with issues in Preclinical imaging, Dendrite, Anatomy and Visual cortex.

His Calcium imaging research includes themes of Calcium signaling, Neural coding, Cortex, Tactile stimuli and Brain mapping. Fritjof Helmchen interconnects Biophysics and Microscopy in the investigation of issues within Two-photon excitation microscopy. His Microscopy study integrates concerns from other disciplines, such as Microscope, Laser and Fluorescence-lifetime imaging microscopy.

He most often published in these fields:

  • Neuroscience (68.37%)
  • Neocortex (25.12%)
  • Calcium imaging (22.33%)

What were the highlights of his more recent work (between 2018-2021)?

  • Neuroscience (68.37%)
  • Calcium imaging (22.33%)
  • Sensory system (19.07%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Neuroscience, Calcium imaging, Sensory system, Stimulus and Premovement neuronal activity. His research combines Serotonergic and Neuroscience. His work deals with themes such as Resampling, Noise and Inference, which intersect with Calcium imaging.

His studies deal with areas such as Somatosensory system and Posterior parietal cortex as well as Sensory system. The Somatosensory system study combines topics in areas such as Dorsum, Anatomy and Spinal cord. His research integrates issues of Cortex and Auditory area in his study of Neocortex.

Between 2018 and 2021, his most popular works were:

  • The mesoSPIM initiative: open-source light-sheet microscopes for imaging cleared tissue (57 citations)
  • High-density multi-fiber photometry for studying large-scale brain circuit dynamics (43 citations)
  • High-density multi-fiber photometry for studying large-scale brain circuit dynamics (43 citations)

In his most recent research, the most cited papers focused on:

  • Neuroscience
  • Neuron
  • Gene

His primary scientific interests are in Neuroscience, Calcium imaging, Somatosensory system, Sensory system and Brain mapping. The study incorporates disciplines such as Serotonergic and Serotonin in addition to Neuroscience. His research in Calcium imaging focuses on subjects like Barrel cortex, which are connected to Auditory area, Cortex and Neocortex.

His work on Sensory cortex and Whisking in animals as part of general Somatosensory system research is often related to Lateral Orbitofrontal Cortex and Value, thus linking different fields of science. His Premovement neuronal activity research includes elements of Hippocampal formation, Spatial light modulator, Optical fiber and Brain circuit. The various areas that Fritjof Helmchen examines in his Optogenetics study include Photostimulation, Fluoxetine and Cognition.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Deep tissue two-photon microscopy

Fritjof Helmchen;Winfried Denk.
Nature Methods (2005)

4003 Citations

Fluctuations and stimulus−induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex

David Kleinfeld;Partha P. Mitra;Fritjof Helmchen;Winfried Denk.
Proceedings of the National Academy of Sciences of the United States of America (1998)

854 Citations

Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo

Axel Nimmerjahn;Frank Kirchhoff;Jason N D Kerr;Fritjof Helmchen.
Nature Methods (2004)

852 Citations

Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance.

Linda Madisen;Aleena R. Garner;Daisuke Shimaoka;Amy S. Chuong.
Neuron (2015)

808 Citations

A Miniature Head-Mounted Two-Photon Microscope: High-Resolution Brain Imaging in Freely Moving Animals

Fritjof Helmchen;Michale S. Fee;David W. Tank;Winfried Denk.
Neuron (2001)

740 Citations

Ca2+ buffering and action potential-evoked Ca2+ signaling in dendrites of pyramidal neurons

Fritjof Helmchen;K. Imoto;Bert Sakmann.
Biophysical Journal (1996)

687 Citations

high-speed in vivo calcium imaging reveals neuronal network activity with near-millisecond precision

Benjamin F Grewe;Dominik Langer;Hansjörg Kasper;Björn M Kampa.
Nature Methods (2010)

549 Citations

Imaging input and output of neocortical networks in vivo

Jason N. D. Kerr;David Greenberg;Fritjof Helmchen.
Proceedings of the National Academy of Sciences of the United States of America (2005)

549 Citations

Lentivirus-based genetic manipulations of cortical neurons and their optical and electrophysiological monitoring in vivo

Tanjew Dittgen;Axel Nimmerjahn;Shoji Komai;Pawel Licznerski.
Proceedings of the National Academy of Sciences of the United States of America (2004)

526 Citations

Pre- and postsynaptic whole-cell recordings in the medial nucleus of the trapezoid body of the rat.

J. G. G. Borst;F. Helmchen;B. Sakmann.
The Journal of Physiology (1995)

480 Citations

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