2019 - Fellow of the American Association for the Advancement of Science (AAAS)
His primary areas of study are Fibroblast growth factor, Cell biology, Internal medicine, Endocrinology and Fibroblast growth factor receptor. He regularly ties together related areas like Signal transduction in his Fibroblast growth factor studies. The various areas that David M. Ornitz examines in his Cell biology study include Genetics, SLIT3, Cellular differentiation, Mesoderm and FGF10.
David M. Ornitz combines subjects such as Dwarfism and Chondrocyte, Endochondral bone growth, Endochondral ossification with his study of Internal medicine. His Endocrinology research is multidisciplinary, relying on both FGF8, Heart development, Indian hedgehog, SOX9 and Limb development. David M. Ornitz interconnects Mutation, Missense mutation, Ligand, Alternative splicing and Fibroblast growth factor receptor 1 in the investigation of issues within Fibroblast growth factor receptor.
David M. Ornitz spends much of his time researching Fibroblast growth factor, Cell biology, Internal medicine, Endocrinology and Fibroblast growth factor receptor. The subject of his Fibroblast growth factor research is within the realm of Receptor. His Cell biology research integrates issues from Chondrocyte and Cellular differentiation.
His Internal medicine research incorporates elements of Limb bud, Heart development and Cardiology. His Endocrinology research focuses on FGF18 and how it relates to Chondrogenesis. His studies in Fibroblast growth factor receptor integrate themes in fields like Molecular biology, Cancer research and Ligand.
His primary areas of investigation include Cell biology, Fibroblast growth factor, Fibroblast growth factor receptor 1, Cancer research and FGF20. The Cell biology study combines topics in areas such as Limb bud and Hair cell, Organ of Corti, Cochlea. His Fibroblast growth factor study incorporates themes from PI3K/AKT/mTOR pathway and Signal transduction.
His research in Fibroblast growth factor receptor 1 intersects with topics in Fibroblast, Endocrinology and Insulin resistance. In the subject of general Cancer research, his work in Angiogenesis is often linked to Bleomycin, thereby combining diverse domains of study. His Fibroblast growth factor receptor research is multidisciplinary, incorporating elements of DUX4, Homeostasis and Osteoblast.
The scientist’s investigation covers issues in Fibroblast growth factor, Cell biology, Cancer research, Mesenchyme and Angiogenesis. His Fibroblast growth factor study is mostly concerned with Fibroblast growth factor receptor, FGF9 and FGF10. His work deals with themes such as Limb bud and FGF18, which intersect with Cell biology.
His Cancer research research is multidisciplinary, incorporating perspectives in Fibroblast growth factor receptor 1, Pulmonary fibrosis and Lung injury. His Mesenchyme research incorporates themes from Cell signaling, Endochondral ossification, Intramembranous ossification and Osteoblast. He focuses mostly in the field of Angiogenesis, narrowing it down to topics relating to Carcinogenesis and, in certain cases, Immune system, Lung cancer, Adenocarcinoma and Tyrosine kinase.
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Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor.
Avner Yayon;Michael Klagsbrun;Jeffrey D. Esko;Philip Leder.
Cell (1991)
Fibroblast growth factors.
David M Ornitz;Nobuyuki Itoh.
Genome Biology (2001)
Receptor specificity of the fibroblast growth factor family.
David M. Ornitz;Jingsong Xu;Jennifer S. Colvin;Donald G. McEwen.
Journal of Biological Chemistry (1996)
Evolution of the Fgf and Fgfr gene families
Nobuyuki Itoh;David M. Ornitz.
Trends in Genetics (2004)
Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers
Ramaswamy Govindan;Li Ding;Malachi Griffith;Janakiraman Subramanian.
Cell (2012)
The Fibroblast Growth Factor signaling pathway
David M. Ornitz;Nobuyuki Itoh.
Wiley Interdisciplinary Reviews-Developmental Biology (2015)
Receptor Specificity of the Fibroblast Growth Factor Family THE COMPLETE MAMMALIAN FGF FAMILY
Xiuqin Zhang;Omar A. Ibrahimi;Shaun K. Olsen;Hisashi Umemori.
Journal of Biological Chemistry (2006)
FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease.
David M. Ornitz;Pierre J. Marie.
Genes & Development (2002)
FGFs, heparan sulfate and FGFRs: complex interactions essential for development
David M. Ornitz.
BioEssays (2000)
Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.
Jennifer S. Colvin;Barbara A. Bohne;Gary W. Harding;Donald G. McEwen.
Nature Genetics (1996)
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