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Molecular Biology

D-Index
75
Citations
20907
World Ranking
1190
National Ranking
617

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jeanne M. Nerbonne is affiliated with Washington University in St. Louis in the United States. Their research spans several fields, notably Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience. Within these areas, they have a significant focus on Molecular Biology, Cardiology and Cardiovascular Medicine, and Cellular and Molecular Neuroscience, among other specialized subfields.

Their work extensively covers topics related to Ion channel regulation and function, Cardiac electrophysiology and arrhythmias, Fibroblast Growth Factor Research, and Neuroscience and Neuropharmacology Research. Additional research interests include Cardiomyopathy and Myosin Studies, Circadian rhythm and melatonin, and Receptor Mechanisms and Signaling.

Jeanne M. Nerbonne's publication record includes several recent papers such as:

  • Integrated multi-omic characterization of congenital heart disease (2022) published in Nature
  • Mechanical dysfunction of the sarcomere induced by a pathogenic mutation in troponin T drives cellular adaptation (2021) published in The Journal of General Physiology
  • Polycystin 2 is increased in disease to protect against stress-induced cell death (2020) published in Scientific Reports
  • Identification of structures for ion channel kinetic models (2021) published in PLoS Computational Biology
  • Molecular, Cellular and Functional Changes in the Retinas of Young Adult Mice Lacking the Voltage-Gated K+ Channel Subunits Kv8.2 and K2.1 (2021) published in International Journal of Molecular Sciences

They have frequent co-authorships with several researchers, including:

  • Jonathan R. Silva
  • Rebecca L. Mellor
  • Paweorn Angsutararux
  • Tracey O. Hermanstyne
  • Nien-Du Yang

Jeanne M. Nerbonne's studies have been disseminated notably through frequent publication in venues such as bioRxiv (Cold Spring Harbor Laboratory), The Journal of General Physiology, and the IUPHAR/BPS Guide to Pharmacology CITE. Additional publication venues include Circulation Arrhythmia and Electrophysiology and Biophysical Journal.

They were recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP.

    Guoping Feng;Rebecca H. Mellor;Michael Bernstein;Cynthia Keller-Peck

  • Molecular basis of functional voltage-gated K+ channel diversity in the mammalian myocardium.

    Unknown

  • Deep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNAs in Failing Human Heart and Remodeling With Mechanical Circulatory Support

    Kai-Chien Yang;Kathryn A. Yamada;Akshar Y. Patel;Veli K. Topkara

  • Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk.

    Yun Chen;György Csordás;Casey Jowdy;Timothy G. Schneider

  • Functional Knockout of the Transient Outward Current, Long-QT Syndrome, and Cardiac Remodeling in Mice Expressing a Dominant-Negative Kv4 α Subunit

    Dianne M. Barry;Haodong Xu;Richard B. Schuessler;Jeanne M. Nerbonne

  • Genetic Manipulation of Cardiac K Channel Function in Mice What Have We Learned, and Where Do We Go From Here?

    Jeanne M. Nerbonne;Colin G. Nichols;Thomas L. Schwarz;Denis Escande

  • Differential Expression of Voltage-Gated K+ Channel Subunits in Adult Rat Heart : Relation to Functional K+ Channels?

    Dianne M. Barry;James S. Trimmer;John P. Merlie;Jeanne M. Nerbonne

  • Molecular basis of transient outward K+ current diversity in mouse ventricular myocytes

    Unknown

  • Mediation of Neuronal Apoptosis by Kv2.1-Encoded Potassium Channels

    Sumon Pal;Karen A. Hartnett;Jeanne M. Nerbonne;Edwin S. Levitan

  • Molecular Determinants of Cardiac Transient Outward Potassium Current (Ito) Expression and Regulation

    Unknown

  • The Kv4.2 Potassium Channel Subunit Is Required for Pain Plasticity

    Hui-Juan Hu;Yarimar Carrasquillo;Farzana Karim;Wonil E. Jung

  • Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons.

    Guojun Bu;Esther A. Maksymovitch;Jeanne M. Nerbonne;Alan L. Schwartz

  • Distinct transient outward potassium current (Ito) phenotypes and distribution of fast-inactivating potassium channel alpha subunits in ferret left ventricular myocytes.

    Mulugu V. Brahmajothi;Donald L. Campbell;Randall L. Rasmusson;Michael J. Morales

  • Attenuation of the Slow Component of Delayed Rectification, Action Potential Prolongation, and Triggered Activity in Mice Expressing a Dominant-Negative Kv2 α Subunit

    Unknown

  • Mesp1 Coordinately Regulates Cardiovascular Fate Restriction and Epithelial-Mesenchymal Transition in Differentiating ESCs

    R. Coleman Lindsley;Jennifer G. Gill;Theresa L. Murphy;Ellen M. Langer

  • Delayed Rectifier K+ Currents,IK, Are Encoded by Kv2 α-Subunits and Regulate Tonic Firing in Mammalian Sympathetic Neurons

    Unknown

  • Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels.

    Jun Yang Lou;Fernanda Laezza;Benjamin R. Gerber;Maolei Xiao

  • Targeted Deletion of Kv4.2 Eliminates I to,f and Results in Electrical and Molecular Remodeling, With No Evidence of Ventricular Hypertrophy or Myocardial Dysfunction

    Weinong Guo;W. Edward Jung;Céline Marionneau;Franck Aimond

  • Expression of Distinct ERG Proteins in Rat, Mouse, and Human Heart RELATION TO FUNCTIONAL I Kr CHANNELS

    Unknown

  • Neurotechnique Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP

    Guoping Feng;Rebecca H. Mellor;Michael Bernstein;Cynthia Keller-Peck

Frequent Co-Authors

David M. Ornitz
David M. Ornitz Washington University in St. Louis
James S. Trimmer
James S. Trimmer University of California, Davis
Andreas Burkhalter
Andreas Burkhalter Washington University in St. Louis
Raymond R. Townsend
Raymond R. Townsend University of Pennsylvania
Joan Heller Brown
Joan Heller Brown University of California, San Diego
Erik D. Herzog
Erik D. Herzog Washington University in St. Louis
Mark E. Anderson
Mark E. Anderson Johns Hopkins University
Joshua R. Sanes
Joshua R. Sanes Harvard University
Ann Marie Craig
Ann Marie Craig University of British Columbia

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