Joan Heller Brown

Overview

Best Publications

• Cardiac Muscle Cell Hypertrophy and Apoptosis Induced by Distinct Members of the p38 Mitogen-activated Protein Kinase Family

  Yibin Wang;Shuang Huang;Valerie P. Sah;John Ross

  1083
  Citations

• Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy.

  H E Shubeita;P M McDonough;A N Harris;K U Knowlton

  975
  Citations

• The δC Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure

  Tong Zhang;Lars S. Maier;Lars S. Maier;Nancy D. Dalton;Shigeki Miyamoto

  705
  Citations

• Enhanced Gαq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure

  John W. Adams;Yoshihito Sakata;Michael G. Davis;Valerie P. Sah

  688
  Citations

• Cardiotrophin 1 (CT-1) Inhibition of Cardiac Myocyte Apoptosis via a Mitogen-activated Protein Kinase-dependent Pathway DIVERGENCE FROM DOWNSTREAM CT-1 SIGNALS FOR MYOCARDIAL CELL HYPERTROPHY

  Zelin Sheng;Kirk Knowlton;Ju Chen;Masahiko Hoshijima

  589
  Citations

• Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

  Stefan Wagner;Nataliya Dybkova;Eva C.L. Rasenack;Claudius Jacobshagen

  580
  Citations

• Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling.

  Xu Wu;Tong Zhang;Julie B C Bossuyt;Xiaodong Li

  573
  Citations

• Transgenic CaMKIIδC Overexpression Uniquely Alters Cardiac Myocyte Ca2+ Handling. Reduced SR Ca2+ Load and Activated SR Ca2+ Release

  Lars S. Maier;Tong Zhang;Lu Chen;Jaime DeSantiago

  573
  Citations

• Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II

  Wei-Zhong Zhu;Shi-Qiang Wang;Khalid Chakir;Dongmei Yang

  541
  Citations

• CaMKII in myocardial hypertrophy and heart failure.

  Mark E. Anderson;Joan Heller Brown;Donald M. Bers

  520
  Citations

• The role of Rho in G protein-coupled receptor signal transduction.

  Valerie P. Sah;Tammy M. Seasholtz;Sarah A. Sagi;Joan Heller Brown

  452
  Citations

• Requirement for Ca2+/calmodulin–dependent kinase II in the transition from pressure overload–induced cardiac hypertrophy to heart failure in mice

  Haiyun Ling;Tong Zhang;Laetitia Pereira;Christopher Kable Means

  444
  Citations

• The Rac and Rho Hall of Fame: A Decade of Hypertrophic Signaling Hits

  Joan Heller Brown;Dominic P. Del Re;Mark A. Sussman

  430
  Citations

• Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-jun NH2-terminal kinase in ventricular muscle cells

  Yibin Wang;Bing Su;Valerie P. Sah;Joan Heller Brown

  424
  Citations

• Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

  John W. Elrod;Renee Wong;Shikha Mishra;Ronald J. Vagnozzi

  421
  Citations

• Rho and Rho Kinase Mediate Thrombin-Stimulated Vascular Smooth Muscle Cell DNA Synthesis and Migration

  Tammy M. Seasholtz;Mousumi Majumdar;Daniel D. Kaplan;Joan Heller Brown

  414
  Citations

• Stimulation by Dopamine of Adenylate Cyclase in Retinal Homogenates and of Adenosine-3′:5′-Cyclic Monophosphate Formation in Intact Retina

  Joan Heller Brown;Maynard H. Makman

  404
  Citations

• Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II

  S Miyamoto;A N Murphy;J H Brown

  402
  Citations

• Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes.

  M Pucéat;R Hilal-Dandan;B Strulovici;L L Brunton

  398
  Citations

• Cardiac Muscle Cell Hypertrophy and Apoptosis Induced by Distinct Members of the p38 Mitogen-activated Protein

  Yibin Wang;Shuang Huang;Valerie P. Sah;Joan Heller Brown

  0
  Citations