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Biology and Biochemistry

D-Index
59
Citations
23262
World Ranking
12263
National Ranking
5243

Overview

Dwayne G. Stupack is affiliated with the University of California, San Diego in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular and cellular mechanisms related to cancer and immune response.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad fields, their research further specializes in several subfields such as:

  • Molecular Biology
  • Cell Biology
  • Immunology and Allergy
  • Oncology
  • Immunology

The main topics covered in Stupack's research are diverse and include:

  • Cell Adhesion Molecules Research
  • Ovarian cancer diagnosis and treatment
  • Cellular Mechanics and Interactions
  • Immunotherapy and Immune Responses
  • Cell death mechanisms and regulation
  • Cancer Mechanisms and Therapy
  • Ubiquitin and proteasome pathways

The scientist has published extensively with frequent appearances in the following publication venues:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature reviews. Cancer
  • Cancers
  • Journal of Translational Medicine

Recent papers authored or co-authored by Dwayne G. Stupack include:

  • Targeting FAK in anticancer combination therapies, 2021, Nature reviews. Cancer
  • Nonsense-mediated RNA decay: an emerging modulator of malignancy, 2022, Nature reviews. Cancer
  • Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis, 2022, Proceedings of the National Academy of Sciences
  • Association of Copy Number Variation Signature and Survival in Patients With Serous Ovarian Cancer, 2021, JAMA Network Open
  • Caspase-8 as a novel mediator linking Src kinase signaling to enhanced glioblastoma malignancy, 2022, Cell Death and Differentiation

Frequent collaborators in their research include:

  • David D. Schlaepfer
  • Marjaana Ojalill
  • Xiao Lei Chen
  • Duygu Ozmadenci
  • Elise Tahon

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Get a ligand, get a life: integrins, signaling and cell survival.

    Dwayne G. Stupack;David A. Cheresh

  • Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

    Dwayne G. Stupack;Xose S. Puente;Souphaphone Boutsaboualoy;Chris M. Storgard

  • Role of Raf in Vascular Protection from Distinct Apoptotic Stimuli

    Alireza Alavi;John D. Hood;Ricardo Frausto;Dwayne G. Stupack

  • Decreased angiogenesis and arthritic disease in rabbits treated with an αvβ3 antagonist

    Chris M. Storgard;Dwayne G. Stupack;Alfred Jonczyk;Simon L. Goodman

  • Src-mediated coupling of focal adhesion kinase to integrin αvβ5 in vascular endothelial growth factor signaling

    Brian P. Eliceiri;Xose S. Puente;John D. Hood;Dwayne G. Stupack

  • Integrins and angiogenesis.

    D G Stupack;D A Cheresh

  • Adenovirus Endocytosis Requires Actin Cytoskeleton Reorganization Mediated by Rho Family GTPases

    Erguang Li;Dwayne Stupack;Gary M. Bokoch;Glen R. Nemerow

  • Adenovirus endocytosis via alpha(v) integrins requires phosphoinositide-3-OH kinase.

    Erguang Li;Dwayne Stupack;Richard Klemke;David A. Cheresh

  • Potentiation of neuroblastoma metastasis by loss of caspase-8.

    Dwayne G. Stupack;Tal Teitz;Matthew D. Potter;David Mikolon

  • A homing mechanism for bone marrow–derived progenitor cell recruitment to the neovasculature

    Hui Jin;Aparna Aiyer;Jingmei Su;Per Borgstrom

  • Integrin αvβ1 Is an Adenovirus Coreceptor

    Erguang Li;Swati L. Brown;Dwayne G. Stupack;Xose S. Puente

  • X‐Ray Computed Tomography Imaging of Breast Cancer by using Targeted Peptide‐Labeled Bismuth Sulfide Nanoparticles

    Joseph M. Kinsella;Rebecca E. Jimenez;Priya P. Karmali;Anthony M. Rush

  • ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands.

    Dwayne G. Stupack;David A. Cheresh

  • Targeting FAK in anticancer combination therapies.

    John C Dawson;Alan Serrels;Dwayne G Stupack;David D Schlaepfer

  • Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors.

    Mitra Sk;Mikolon D;Molina Je;Hsia Da;Hsia Da

  • Mechanisms and Consequences of Affinity Modulation of Integrin αVβ3 Detected with a Novel Patch-engineered Monovalent Ligand

    Nisar Pampori;Takaaki Hato;Dwayne G. Stupack;Sallouha Aidoudi

  • Hepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1α and Stimulates the Synthesis of Vascular Endothelial Growth Factor

    Nasimuzzaman;Gulam Waris;David Mikolon;Dwayne G. Stupack

  • PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.

    Isabelle Tanjoni;Colin Walsh;Sean Uryu;Alok Tomar

  • Caspase-8 as a therapeutic target in cancer.

    Dwayne G. Stupack

Frequent Co-Authors

David D. Schlaepfer
David D. Schlaepfer University of California, San Diego
David A. Cheresh
David A. Cheresh University of California, San Diego
Glen R. Nemerow
Glen R. Nemerow Scripps Research Institute
Rong Xiang
Rong Xiang Nankai University
Sanford J. Shattil
Sanford J. Shattil University of California, San Diego
Shunichi Shimasaki
Shunichi Shimasaki University of California, San Diego
Joan Heller Brown
Joan Heller Brown University of California, San Diego
Ralph A. Reisfeld
Ralph A. Reisfeld Scripps Research Institute
Richard L. Klemke
Richard L. Klemke University of California, San Diego
Jill M. Lahti
Jill M. Lahti St. Jude Children's Research Hospital

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