The scientist’s investigation covers issues in Cell biology, Diacylglycerol kinase, Signal transduction, Biochemistry and Phosphatidic acid. Her work carried out in the field of Cell biology brings together such families of science as T cell, T-cell receptor, KDEL and Brefeldin A. Her Diacylglycerol kinase study is concerned with the larger field of Kinase.
Her Kinase research is multidisciplinary, incorporating elements of Caenorhabditis elegans, Intracellular and Cell membrane. Her Signal transduction study incorporates themes from Moesin, Jurkat cells and Transport protein. Her studies in Phosphatidic acid integrate themes in fields like Receptor and Phosphorylation.
Isabel Mérida spends much of her time researching Cell biology, Diacylglycerol kinase, Biochemistry, Signal transduction and Kinase. In her study, Cell culture is inextricably linked to Receptor, which falls within the broad field of Cell biology. Her Diacylglycerol kinase research includes elements of T cell, PI3K/AKT/mTOR pathway, Phosphatidic acid and Second messenger system.
Her research integrates issues of Jurkat cells, Cell growth and Cell membrane in her study of Signal transduction. Her studies deal with areas such as Phospholipase D and Cancer immunotherapy as well as Kinase. The study incorporates disciplines such as Molecular biology, Tyrosine and Phosphatidylethanolamine N-methyltransferase in addition to Phosphorylation.
Her primary scientific interests are in Cell biology, Diacylglycerol kinase, T cell, Protein kinase C and Cytotoxic T cell. She has included themes like Immunological synapse, T-cell receptor and Gene silencing in her Cell biology study. The Diacylglycerol kinase portion of her research involves studies in Kinase and Signal transduction.
Her Kinase research incorporates elements of Phosphatidic acid and Cancer immunotherapy. Isabel Mérida has researched T cell in several fields, including Cancer research and Immunotherapy. Her work investigates the relationship between Cytotoxic T cell and topics such as CD8 that intersect with problems in Cell culture, Cell, Interleukin 15, Interleukin 2 and Biochemistry.
Her main research concerns Cell biology, Diacylglycerol kinase, Gene silencing, Sorting nexin and SNX27. The various areas that she examines in her Cell biology study include Interleukin 21, IL-2 receptor and Antigen-presenting cell. Her Diacylglycerol kinase research is under the purview of Signal transduction.
Her work deals with themes such as Protein kinase C and Kinase, which intersect with Gene silencing. Her Sorting nexin study combines topics from a wide range of disciplines, such as Immunological synapse, PDZ domain, Interactome, DLG1 and Retromer. Isabel Mérida combines subjects such as T lymphocyte and Phosphatidic acid with her study of SNX27.
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Diacylglycerol kinases : at the hub of cell signalling
Isabel Mérida;Antonia Ávila-Flores;Ernesto Merino.
Biochemical Journal (2008)
Diacylglycerol, when simplicity becomes complex
Silvia Carrasco;Isabel Mérida.
Trends in Biochemical Sciences (2007)
Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3‐kinase
Concepción Jimenez;David R. Jones;Pablo Rodríguez‐Viciana;Ana Gonzalez‐García.
The EMBO Journal (1998)
Identification of Insulin-like Growth Factor-binding Protein-1 as a Potential Physiological Substrate for Human Stromelysin-3
Santos Mañes;Emilia Mira;Maria del Mar Barbacid;Angel Ciprés.
Journal of Biological Chemistry (1997)
Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis.
M Vicente-Manzanares;M Rey;D R Jones;D Sancho.
Journal of Immunology (1999)
Modulation of the Mammalian Target of Rapamycin Pathway by Diacylglycerol Kinase-produced Phosphatidic Acid *
Antonia Ávila-Flores;Teresa Santos;Esther Rincón;Isabel Mérida.
Journal of Biological Chemistry (2005)
Role of diacylglycerol kinase α in the attenuation of receptor signaling
Miguel Angel Sanjuán;David R. Jones;Manuel Izquierdo;Isabel Mérida.
Journal of Cell Biology (2001)
Glucose transport and antilipolysis are differentially regulated by the polar head group of an insulin-sensitive glycophospholipid
Kathleen L. Kelly;Jose M. Mato;Isabel Merida;Leonard Jarett.
Proceedings of the National Academy of Sciences of the United States of America (1987)
Diacylglycerol-dependent Binding Recruits PKCθ and RasGRP1 C1 Domains to Specific Subcellular Localizations in Living T Lymphocytes
Silvia Carrasco;Isabel Merida.
Molecular Biology of the Cell (2004)
IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase.
I Merida;E Diez;G N Gaulton.
Journal of Immunology (1991)
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