D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 44 Citations 6,423 117 World Ranking 16370 National Ranking 363

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • Signal transduction

The scientist’s investigation covers issues in Cell biology, Diacylglycerol kinase, Signal transduction, Biochemistry and Phosphatidic acid. Her work carried out in the field of Cell biology brings together such families of science as T cell, T-cell receptor, KDEL and Brefeldin A. Her Diacylglycerol kinase study is concerned with the larger field of Kinase.

Her Kinase research is multidisciplinary, incorporating elements of Caenorhabditis elegans, Intracellular and Cell membrane. Her Signal transduction study incorporates themes from Moesin, Jurkat cells and Transport protein. Her studies in Phosphatidic acid integrate themes in fields like Receptor and Phosphorylation.

Her most cited work include:

  • Diacylglycerol kinases : at the hub of cell signalling (334 citations)
  • Diacylglycerol, when simplicity becomes complex (266 citations)
  • Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3‐kinase (251 citations)

What are the main themes of her work throughout her whole career to date?

Isabel Mérida spends much of her time researching Cell biology, Diacylglycerol kinase, Biochemistry, Signal transduction and Kinase. In her study, Cell culture is inextricably linked to Receptor, which falls within the broad field of Cell biology. Her Diacylglycerol kinase research includes elements of T cell, PI3K/AKT/mTOR pathway, Phosphatidic acid and Second messenger system.

Her research integrates issues of Jurkat cells, Cell growth and Cell membrane in her study of Signal transduction. Her studies deal with areas such as Phospholipase D and Cancer immunotherapy as well as Kinase. The study incorporates disciplines such as Molecular biology, Tyrosine and Phosphatidylethanolamine N-methyltransferase in addition to Phosphorylation.

She most often published in these fields:

  • Cell biology (63.48%)
  • Diacylglycerol kinase (55.65%)
  • Biochemistry (33.91%)

What were the highlights of her more recent work (between 2016-2021)?

  • Cell biology (63.48%)
  • Diacylglycerol kinase (55.65%)
  • T cell (21.74%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Cell biology, Diacylglycerol kinase, T cell, Protein kinase C and Cytotoxic T cell. She has included themes like Immunological synapse, T-cell receptor and Gene silencing in her Cell biology study. The Diacylglycerol kinase portion of her research involves studies in Kinase and Signal transduction.

Her Kinase research incorporates elements of Phosphatidic acid and Cancer immunotherapy. Isabel Mérida has researched T cell in several fields, including Cancer research and Immunotherapy. Her work investigates the relationship between Cytotoxic T cell and topics such as CD8 that intersect with problems in Cell culture, Cell, Interleukin 15, Interleukin 2 and Biochemistry.

Between 2016 and 2021, her most popular works were:

  • Diacylglycerol kinases in cancer. (38 citations)
  • Diacylglycerol kinase control of protein kinase C. (15 citations)
  • Predominant contribution of DGKζ over DGKα in the control of PKC/PDK-1-regulated functions in T cells. (15 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Signal transduction

Her main research concerns Cell biology, Diacylglycerol kinase, Gene silencing, Sorting nexin and SNX27. The various areas that she examines in her Cell biology study include Interleukin 21, IL-2 receptor and Antigen-presenting cell. Her Diacylglycerol kinase research is under the purview of Signal transduction.

Her work deals with themes such as Protein kinase C and Kinase, which intersect with Gene silencing. Her Sorting nexin study combines topics from a wide range of disciplines, such as Immunological synapse, PDZ domain, Interactome, DLG1 and Retromer. Isabel Mérida combines subjects such as T lymphocyte and Phosphatidic acid with her study of SNX27.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Diacylglycerol kinases : at the hub of cell signalling

Isabel Mérida;Antonia Ávila-Flores;Ernesto Merino.
Biochemical Journal (2008)

414 Citations

Diacylglycerol, when simplicity becomes complex

Silvia Carrasco;Isabel Mérida.
Trends in Biochemical Sciences (2007)

413 Citations

Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3‐kinase

Concepción Jimenez;David R. Jones;Pablo Rodríguez‐Viciana;Ana Gonzalez‐García.
The EMBO Journal (1998)

330 Citations

Identification of Insulin-like Growth Factor-binding Protein-1 as a Potential Physiological Substrate for Human Stromelysin-3

Santos Mañes;Emilia Mira;Maria del Mar Barbacid;Angel Ciprés.
Journal of Biological Chemistry (1997)

271 Citations

Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis.

M Vicente-Manzanares;M Rey;D R Jones;D Sancho.
Journal of Immunology (1999)

189 Citations

Modulation of the Mammalian Target of Rapamycin Pathway by Diacylglycerol Kinase-produced Phosphatidic Acid *

Antonia Ávila-Flores;Teresa Santos;Esther Rincón;Isabel Mérida.
Journal of Biological Chemistry (2005)

171 Citations

Role of diacylglycerol kinase α in the attenuation of receptor signaling

Miguel Angel Sanjuán;David R. Jones;Manuel Izquierdo;Isabel Mérida.
Journal of Cell Biology (2001)

171 Citations

Glucose transport and antilipolysis are differentially regulated by the polar head group of an insulin-sensitive glycophospholipid

Kathleen L. Kelly;Jose M. Mato;Isabel Merida;Leonard Jarett.
Proceedings of the National Academy of Sciences of the United States of America (1987)

161 Citations

Diacylglycerol-dependent Binding Recruits PKCθ and RasGRP1 C1 Domains to Specific Subcellular Localizations in Living T Lymphocytes

Silvia Carrasco;Isabel Merida.
Molecular Biology of the Cell (2004)

155 Citations

IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase.

I Merida;E Diez;G N Gaulton.
Journal of Immunology (1991)

150 Citations

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