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Naoaki Saito

Naoaki Saito

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
14877
World Ranking
6444
National Ranking
420

Overview

Naoaki Saito is affiliated with Kobe University in Japan, focusing primarily on research spanning biochemistry, genetics, molecular biology, and neuroscience. Their body of work has contributed extensively to understanding molecular and cellular mechanisms within these fields.

Their research spans several main fields of study including:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

The subfields addressed in their publications further refine their expertise and include:

  • Molecular Biology
  • Sensory Systems
  • Neurology
  • Cell Biology
  • Cellular and Molecular Neuroscience

Main topics covered by their research encompass:

  • Hearing, Cochlea, Tinnitus, Genetics
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Protein Kinase Regulation and GTPase Signaling
  • Acoustic Wave Phenomena Research
  • Melanin and Skin Pigmentation
  • Receptor Mechanisms and Signaling
  • Neuroscience and Neuropharmacology Research

Recent papers authored or co-authored by Saito include:

  • "Nox3-Derived Superoxide in Cochleae Induces Sensorineural Hearing Loss" (2021, Journal of Neuroscience)
  • "The integrity of cochlear hair cells is established and maintained through the localization of Dia1 at apical junctional complexes and stereocilia" (2020, Cell Death and Disease)
  • "DGKγ Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCγ" (2020, eNeuro)
  • "S-Palmitoylation of Tyrosinase at Cysteine500 Regulates Melanogenesis" (2022, Journal of Investigative Dermatology)
  • "Phosphoproteomic of the acetylcholine pathway enables discovery of the PKC-β-PIX-Rac1-PAK cascade as a stimulatory signal for aversive learning" (2022, Molecular Psychiatry)

Frequent coauthors collaborating with Naoaki Saito comprise:

  • Takehiko Ueyama
  • Hirofumi Sakaguchi
  • Hiroaki Mohri
  • Yuzuru Ninoyu
  • Naoko Adachi

Saito's research has appeared in various publication venues, notably:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Journal of Neuroscience
  • Cell Death and Disease
  • Journal of Investigative Dermatology
  • Molecular Psychiatry

Best Publications

  • Distribution of protein kinase C-like immunoreactive neurons in rat brain.

    N Saito;U Kikkawa;Y Nishizuka;C Tanaka

  • Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1

    Atsuo Sasaki;Atsuo Sasaki;Takaharu Taketomi;Reiko Kato;Kazuko Saeki

  • Regulation of nuclear translocation of Forkhead transcription factor AFX by protein kinase B

    Hiroshi Takaishi;Hiroaki Konishi;Hidenori Matsuzaki;Yoshitaka Ono

  • Direct Visualization of the Translocation of the γ-Subspecies of Protein Kinase C in Living Cells Using Fusion Proteins with Green Fluorescent Protein

    Norio Sakai;Keiko Sasaki;Natsu Ikegaki;Yasuhito Shirai

  • Protein Kinase Cγ (PKCγ): Function of Neuron Specific Isotype

    Naoaki Saito;Yasuhito Shirai

  • Effects of interferon-α, interferon-γ and cAMP on the transcriptional regulation of the serotonin transporter

    Osamu Morikawa;Norio Sakai;Hidefumi Obara;Naoaki Saito

  • Postnatal development of a brain-specific subspecies of protein kinase C in rat

    T Hashimoto;K Ase;S Sawamura;U Kikkawa

  • Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCε-mediated phosphorylation at S800

    Sravan Mandadi;Tomoko Tominaga;Tomoko Tominaga;Mitsuko Numazaki;Namie Murayama;Namie Murayama

  • Duox maturation factors form cell surface complexes with Duox affecting the specificity of reactive oxygen species generation

    Stanislas Morand;Takehiko Ueyama;Satoshi Tsujibe;Naoaki Saito

  • Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells.

    Elaine C. Larsen;Jeannine A. DiGennaro;Naoaki Saito;Sapna Mehta

  • Activation mechanisms of protein kinase C: maturation, catalytic activation, and targeting.

    Yasuhito Shirai;Naoaki Saito

  • Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2.

    Shun'ichi Kuroda;Shun'ichi Kuroda;Miho Oyasu;Masakatsu Kawakami;Norihiro Kanayama

  • Craniosynostosis in transgenic mice overexpressing Nell-1

    Xinli Zhang;Shun'ichi Kuroda;Dale Carpenter;Ichiro Nishimura

  • Distinct Effects of Fatty Acids on Translocation of γ- and ε-Subspecies of Protein Kinase C

    Yasuhito Shirai;Kaori Kashiwagi;Keiko Yagi;Norio Sakai

  • Three distinct mechanisms for translocation and activation of the δ subspecies of protein kinase C

    Shiho Ohmori;Yasuhito Shirai;Norio Sakai;Motoko Fujii

  • Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain.

    Masakazu Ibi;Kuniharu Matsuno;Dai Shiba;Masato Katsuyama

  • A new neuromodulatory pathway with a glial contribution mediated via A2a adenosine receptors

    T. Nishizaki;K. Nagai;T. Nomura;H. Tada

  • Production of specific antibodies against GABA transporter subtypes (GAT1, GAT2, GAT3) and their application to immunocytochemistry.

    Natsu Ikegaki;Naoaki Saito;Makoto Hashima;Chikako Tanaka

  • Distinct cellular expression of calcineurin Aα and Aβ in rat brain

    Takayoshi Kuno;Hideyuki Mukai;Akira Ito;Chang‐Duk Chang

  • Cellular and intracellular localization of ε-subspecies of protein kinase C in the rat brain; presynaptic localization of the ε-subspecies

    Naoaki Saito;Akiko Itouji;Yoshiki Totani;Ichiro Osawa

Frequent Co-Authors

Chikako Tanaka
Chikako Tanaka Kobe University
Yasutomi Nishizuka
Yasutomi Nishizuka Kobe University
Ushio Kikkawa
Ushio Kikkawa Kobe University
Shun'ichi Kuroda
Shun'ichi Kuroda Osaka University
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Isabel Mérida
Isabel Mérida Spanish National Research Council
Hitoshi Ashida
Hitoshi Ashida Kobe University
Eishichi Miyamoto
Eishichi Miyamoto Kumamoto University
Hideki Sumimoto
Hideki Sumimoto Kyushu University
Tatsushi Toda
Tatsushi Toda University of Tokyo

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