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Yasutomi Nishizuka

Yasutomi Nishizuka

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Biology and Biochemistry
Japan
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
111
Citations
92448
World Ranking
917
National Ranking
44

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award
  • 1992 - Kyoto Prize in Life sciences Elucidation of Intracellular Signal Transduction System through the Discovery and Functional Analysis of the Protein Kinase C
  • 1989 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
  • 1988 - Member of the National Academy of Sciences
  • 1988 - Alfred P. Sloan Jr. Prize, General Motors Cancer Research Foundation
  • 1988 - Canada Gairdner International Award

Overview

Yasutomi Nishizuka was affiliated with Kobe University in Japan during their academic career. Their research contributions were primarily recognized in the life sciences domain, particularly concerning intracellular signal transduction systems.

The scientist received multiple prestigious awards throughout their career, reflecting significant recognition in the field of biomedical research. Among these honors were the Kyoto Prize in Life Sciences in 1992, awarded for the elucidation of intracellular signal transduction systems through the discovery and functional analysis of Protein Kinase C. Nishizuka was also honored with the Albert Lasker Award for Basic Medical Research in 1989 and received the Alfred P. Sloan Jr. Prize from the General Motors Cancer Research Foundation in 1988. Additionally, Nishizuka was elected as a Member of the National Academy of Sciences in 1988 and was a recipient of the Canada Gairdner International Award the same year.

Although specific recent papers, frequent co-authors, publication venues, book publications, main fields and subfields of study or main topics of work were not indicated in the available data, the awards and affiliations suggest a focus on molecular and cellular biology, particularly signal transduction pathways involving key regulatory proteins.

Nishizuka's work contributed to the fundamental understanding of how intracellular enzymes modulate cellular responses, which has implications across multiple aspects of life sciences and biomedical research. The recognition through several internationally respected awards underlines the impact and importance of their research findings within the scientific community.

Best Publications

  • The role of protein kinase C in cell surface signal transduction and tumour promotion

    Yasutomi Nishizuka;Yasutomi Nishizuka

  • Studies and perspectives of protein kinase C

    Yasutomi Nishizuka

  • Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters

    M Castagna;Y Takai;K Kaibuchi;K Sano

  • The molecular heterogeneity of protein kinase C and its implications for cellular regulation

    Yasutomi Nishizuka

  • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

    Yasutomi Nishizuka

  • Protein kinase C and lipid signaling for sustained cellular responses.

    Yasutomi Nishizuka

  • Turnover of inositol phospholipids and signal transduction

    Yasutomi Nishizuka

  • Activation of calcium and phospholipid-dependent protein kinase by diacylglycerol, its possible relation to phosphatidylinositol turnover.

    A. Kishimoto;Y. Takai;T. Mori;U. Kikkawa

  • Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.

    Y Takai;A Kishimoto;Y Iwasa;Y Kawahara

  • Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

    U Kikkawa;Y Takai;R Minakuchi;S Inohara

  • Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

    U Kikkawa;Y Takai;Y Tanaka;R Miyake

  • Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

    M Inoue;A Kishimoto;Y Takai;Y Nishizuka

  • The Protein Kinase C Family: Heterogeneity and its Implications

    Ushio Kikkawa;Akira Kishimoto;Yasutomi Nishizuka

  • Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

    K Kaibuchi;Y Takai;M Sawamura;M Hoshijima

  • Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system

    Yoshimi Takai;Akira Kishimoto;Ushio Kikkawa;Terutoshi Mori

  • Activation of protein kinase C by tyrosine phosphorylation in response to H2O2

    Hiroaki Konishi;Motonari Tanaka;Yukitoshi Takemura;Hidenori Matsuzaki

  • Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease.

    A Kishimoto;N Kajikawa;M Shiota;Y Nishizuka

  • The Role of Protein Kinase C in Transmembrane Signalling

    Ushio Kikkawa;Yasutomi Nishizuka

  • Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties.

    Yoshitaka Ono;Tomoko Fujii;Kouji Ogita;Ushio Kikkawa

  • Diphtheria Toxin-dependent Adenosine Diphosphate Ribosylation of Aminoacyl Transferase II and Inhibition of Protein Synthesis

    Tasuku Honjo;Yasutomi Nishizuka;Osamu Hayaishi;Iwao Kato

Frequent Co-Authors

Ushio Kikkawa
Ushio Kikkawa Kobe University
Yoshimi Takai
Yoshimi Takai Kobe University
Hirohei Yamamura
Hirohei Yamamura Kobe University
Kozo Kaibuchi
Kozo Kaibuchi Nagoya University
Naoaki Saito
Naoaki Saito Kobe University
Chikako Tanaka
Chikako Tanaka Kobe University
Osamu Hayaishi
Osamu Hayaishi Osaka Bioscience Institute
Hiroyuki Nakanishi
Hiroyuki Nakanishi Kumamoto University
Kunihiro Ueda
Kunihiro Ueda Kyoto University
Chiaki Ogino
Chiaki Ogino Kobe University

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