2026 Alexandra C. Newton: Biology and Biochemistry Researcher – H-Index, Publications & Awards

D-Index & Metrics

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	88	2662	2444	1384	1245	309	33801

Discipline name

D-Index

World Ranking

Current World Ranking

National Ranking

Current National Ranking

Publications

Citations

Biology and Biochemistry

2662

2444

1384

1245

309

33801

Biology and Biochemistry

D-Index

Citations

33801

World Ranking

2662

National Ranking

1384

Overview

Alexandra C. Newton is affiliated with the University of California, San Diego in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with substantial contributions to molecular biology and cell biology. Their work extends into cellular and molecular neuroscience, physiology, and genetics.

The scientist's research topics encompass several specific areas including:

Protein Kinase Regulation and GTPase Signaling
PI3K/AKT/mTOR signaling in cancer
Ubiquitin and proteasome pathways
Genetic Neurodegenerative Diseases
Mitochondrial Function and Pathology
Cellular transport and secretion
Microtubule and mitosis dynamics

Notable recent papers by Alexandra C. Newton include:

mTORC2 controls the activity of PKC and Akt by phosphorylating a conserved TOR interaction motif, 2021, Science Signaling
Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus, 2020, Nature Communications
Protein kinase C fusion proteins are paradoxically loss of function in cancer, 2021, Journal of Biological Chemistry
Two Sides of the Same Coin: Protein Kinase C γ in Cancer and Neurodegeneration, 2022, Frontiers in Cell and Developmental Biology
Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model, 2022, Nature Communications

The scientist frequently collaborates with several colleagues including:

Susan S. Taylor
Timothy R. Baffi
Gema Lordén
Alexandr P. Kornev
Maya T. Kunkel

Their publication record shows a strong presence in several journals and platforms, notably:

bioRxiv (Cold Spring Harbor Laboratory)
The FASEB Journal
Journal of Biological Chemistry
Biochemical Journal
Science Signaling

Best Publications

Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells.

David A. Zacharias;Jonathan D. Violin;Alexandra C. Newton;Roger Y. Tsien

2671
Citations
Protein Kinase C: Structure, Function, and Regulation

Alexandra C. Newton

2343
Citations
Regulation of protein kinase C

Alexandra C Newton

1268
Citations
Protein Kinase C: Structural and Spatial Regulation by Phosphorylation, Cofactors, and Macromolecular Interactions

Alexandra C. Newton

1236
Citations
PHLPP: A Phosphatase that Directly Dephosphorylates Akt, Promotes Apoptosis, and Suppresses Tumor Growth

Tianyan Gao;Frank Furnari;Alexandra C. Newton

1119
Citations
Protein kinase C isozymes and the regulation of diverse cell responses

Edward C. Dempsey;Edward C. Dempsey;Alexandra C. Newton;Daria Mochly-Rosen;Alan P. Fields

1064
Citations
Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm.

Alexandra C. Newton

1012
Citations
Regulation of protein kinase C ζ by PI 3-kinase and PDK-1

Margaret M. Chou;Weimin Hou;Joanne Johnson;Lauren K. Graham

815
Citations
Akt/Protein Kinase B Is Regulated by Autophosphorylation at the Hypothetical PDK-2 Site

Alex Toker;Alexandra C. Newton

731
Citations
PHLPP and a Second Isoform, PHLPP2, Differentially Attenuate the Amplitude of Akt Signaling by Regulating Distinct Akt Isoforms

John Brognard;Emma Sierecki;Tianyan Gao;Alexandra C. Newton

695
Citations
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C

Jonathan D Violin;Jin Jin Zhang;Roger Y. Tsien;Alexandra C Newton

646
Citations
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

Valeria Facchinetti;Weiming Ouyang;Hua Wei;Nelyn Soto

637
Citations
Protein kinase C is regulated in vivo by three functionally distinct phosphorylations

Lisa M. Keranen;Erica M. Dutil;Alexandra C. Newton

621
Citations
Protein kinase C: poised to signal

Alexandra C. Newton

593
Citations
Cellular Signaling: Pivoting around PDK-1

Alex Toker;Alexandra C Newton

552
Citations
Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

Erica M. Dutil;Alex Toker;Alexandra C. Newton

529
Citations
Taxonomy and function of C1 protein kinase C homology domains.

James H. Hurley;Alexandra C. Newton;Peter J. Parker;Peter M. Blumberg

467
Citations
Protein kinase C: a paradigm for regulation of protein function by two membrane-targeting modules.

Alexandra C. Newton;Joanne E. Johnson

354
Citations
Mechanism of Interaction of Protein Kinase C with Phorbol Esters REVERSIBILITY AND NATURE OF MEMBRANE ASSOCIATION

Marian Mosior;Alexandra C. Newton

353
Citations
EB2000 symposium report Protein kinase C isozymes and the regulation of diverse cell responses

Edward C. Dempsey;Alexandra C. Newton;Daria Mochly-Rosen;Alan P. Fields

0
Citations