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D-Index & Metrics

Molecular Biology

D-Index
98
Citations
28890
World Ranking
578
National Ranking
317

Research.com Recognitions

  • 2011 - US President's National Medal of Science "For the pioneering discovery that the bacterial cell is controlled by an integrated genetic circuit functioning in time and space that serves as a systems engineering paradigm underlying cell differentiation and ultimately the generation of diversity in all organisms.", President Barack H. Obama in the East Room of the White House on February 1, 2013.
  • 2010 - ASM Lifetime Achievement Award, American Society for Microbiology
  • 1994 - Member of the National Academy of Sciences
  • 1992 - Fellow of the American Academy of Arts and Sciences

Overview

Lucy Shapiro is affiliated with Stanford University in the United States. Their research primarily falls within the field of Biochemistry, Genetics, and Molecular Biology, with a substantial focus on Molecular Biology, Genetics, Ecology, Structural Biology, and Biotechnology.

The scientist's main research topics include:

  • Bacterial Genetics and Biotechnology
  • RNA and protein synthesis mechanisms
  • Bacteriophages and microbial interactions
  • RNA Research and Splicing
  • Advanced Electron Microscopy Techniques and Applications
  • Cancer Research and Treatments
  • Photosynthetic Processes and Mechanisms

Notable recent publications by Lucy Shapiro are:

  • The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems, 2022, Nature Communications
  • Selective sequestration of signalling proteins in a membraneless organelle reinforces the spatial regulation of asymmetry in Caulobacter crescentus, 2020, Nature Microbiology
  • Cryogenic single-molecule fluorescence annotations for electron tomography reveal in situ organization of key proteins in Caulobacter, 2020, Proceedings of the National Academy of Sciences
  • ATP-responsive biomolecular condensates tune bacterial kinase signaling, 2022, Science Advances
  • A modular platform for engineering function of natural and synthetic biomolecular condensates, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors of Lucy Shapiro are:

  • W. E. Moerner
  • Saumya Saurabh
  • Peter D. Dahlberg
  • Trisha N. Chong
  • Keren Lasker

Common publication venues for their work include:

  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Biophysical Journal
  • Nature Communications

Lucy Shapiro has received several awards and honors, such as:

  • US President's National Medal of Science (2011) for discovering that bacterial cells are controlled by integrated genetic circuits functioning in time and space
  • ASM Lifetime Achievement Award, American Society for Microbiology (2010)
  • Member of the National Academy of Sciences (1994)
  • Fellow of the American Academy of Arts and Sciences (1992)

Best Publications

  • Circuit Simulation of Genetic Networks

    Harley H. McAdams;Lucy Shapiro

  • An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.

    Fernando L. Rock;Weimin Mao;Anya Yaremchuk;Mikhail Tukalo

  • Global analysis of the genetic network controlling a bacterial cell cycle.

    Michael T. Laub;Harley H. McAdams;Tamara Feldblyum;Claire M. Fraser

  • Complete genome sequence of Caulobacter crescentus.

    William C. Nierman;Tamara V. Feldblyum;Michael T. Laub;Ian T. Paulsen

  • Cell Cycle Control by an Essential Bacterial Two-Component Signal Transduction Protein

    Kim C Quon;Gregory T Marczynski;Lucy Shapiro

  • MipZ, a Spatial Regulator Coordinating Chromosome Segregation with Cell Division in Caulobacter

    Martin Thanbichler;Lucy Shapiro

  • Rapid and sequential movement of individual chromosomal loci to specific subcellular locations during bacterial DNA replication

    Patrick H. Viollier;Martin Thanbichler;Patrick T. McGrath;Lisandra West

  • Cell Type-Specific Phosphorylation and Proteolysis of a Transcriptional Regulator Controls the G1-to-S Transition in a Bacterial Cell Cycle

    Ibrahim J Domian;Kim C Quon;Lucy Shapiro

  • MreB Actin-Mediated Segregation of a Specific Region of a Bacterial Chromosome

    Zemer Gitai;Natalie Anne Dye;Ann Reisenauer;Masaaki Wachi

  • Genes directly controlled by CtrA, a master regulator of the Caulobacter cell cycle

    Michael T. Laub;Swaine L. Chen;Lucy Shapiro;Harley H. McAdams

  • Codon usage between genomes is constrained by genome-wide mutational processes

    Swaine L. Chen;William Lee;Alison K. Hottes;Lucy Shapiro

  • Negative control of bacterial DNA replication by a cell cycle regulatory protein that binds at the chromosome origin

    Kim C. Quon;Bing Yang;Ibrahim J. Domian;Lucy Shapiro

  • A spindle-like apparatus guides bacterial chromosome segregation

    Jerod L. Ptacin;Steven F. Lee;Ethan C. Garner;Esteban Toro

  • A comprehensive set of plasmids for vanillate- and xylose-inducible gene expression in Caulobacter crescentus

    Martin Thanbichler;Antonio A. Iniesta;Lucy Shapiro

  • An actin-like gene can determine cell polarity in bacteria

    Zemer Gitai;Natalie Dye;Lucy Shapiro

  • Super-resolution imaging in live Caulobacter crescentus cells using photoswitchable EYFP

    Julie S Biteen;Michael A Thompson;Nicole K Tselentis;Grant R Bowman

  • The essential genome of a bacterium.

    Beat Christen;Eduardo Abeliuk;John M Collier;Virginia S Kalogeraki

  • A Polymeric Protein Anchors the Chromosomal Origin/ParB Complex at a Bacterial Cell Pole

    Grant R. Bowman;Luis R. Comolli;Jian Zhu;Michael Eckart

  • Polar localization of a bacterial chemoreceptor.

    M. R. K. Alley;J. R. Maddock;L. Shapiro

  • Cell Cycle–Dependent Polar Localization of an Essential Bacterial Histidine Kinase that Controls DNA Replication and Cell Division

    Christine Jacobs;Ibrahim J. Domian;Janine R. Maddock;Lucy Shapiro

Frequent Co-Authors

W. E. Moerner
W. E. Moerner Stanford University
Harley H. McAdams
Harley H. McAdams Stanford University
Soichi Wakatsuki
Soichi Wakatsuki Stanford University
Zemer Gitai
Zemer Gitai Princeton University
Richard Losick
Richard Losick Harvard University
Susan A. Henry
Susan A. Henry Cornell University
Urs Jenal
Urs Jenal University of Basel
Elizabeth A. Winzeler
Elizabeth A. Winzeler University of California, San Diego

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