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Michael T. Laub

Michael T. Laub

D-Index & Metrics

Molecular Biology

D-Index
70
Citations
21123
World Ranking
1410
National Ranking
718

Overview

Michael T. Laub is affiliated with MIT in the United States and focuses primarily on research in Biochemistry, Genetics, and Molecular Biology, contributing a total of 135 publications in this field. Their work spans several subfields, including Molecular Biology, Genetics, Ecology, Endocrinology, and Plant Science.

The scientist's research covers a range of topics, particularly in bacterial genetics and interactions with bacteriophages, RNA and protein synthesis mechanisms, and protein structure and dynamics. Other areas of study include genomics and phylogenetic studies, CRISPR and genetic engineering, and Vibrio bacteria research.

Recent papers authored or co-authored by Michael T. Laub include:

  • A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome (2022, Nature Microbiology)
  • Toxin-Antitoxin Systems as Phage Defense Elements (2022, Annual Review of Microbiology)
  • Direct activation of a bacterial innate immune system by a viral capsid protein (2022, Nature)
  • The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA (2022, Nature Microbiology)
  • Stress Can Induce Transcription of Toxin-Antitoxin Systems without Activating Toxin (2020, Molecular Cell)

Frequent co-authors in Michael T. Laub's research include Christopher R. Doering, Megan L. Littlehale, Gabriella I. C. Teodoro, Benjamin Wang, and Michele LeRoux.

Typical venues for publishing their work are bioRxiv (Cold Spring Harbor Laboratory), mBio, eLife, Nature Microbiology, and Nature, with the largest number of publications appearing in bioRxiv.

Best Publications

  • Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis

    Elizabeth A. Winzeler;Daniel D. Shoemaker;Anna Astromoff;Hong Liang

  • Specificity in Two-Component Signal Transduction Pathways

    Michael T Laub;Mark Goulian

  • Evolution of Two-Component Signal Transduction Systems

    Emily J. Capra;Michael T. Laub

  • Global analysis of the genetic network controlling a bacterial cell cycle.

    Michael T. Laub;Harley H. McAdams;Tamara Feldblyum;Claire M. Fraser

  • High-Resolution Mapping of the Spatial Organization of a Bacterial Chromosome

    Tung Ba Khanh Le;Maksim Viktorovich Imakaev;Leonid A. Mirny;Michael T. Laub;Michael T. Laub

  • Complete genome sequence of Caulobacter crescentus.

    William C. Nierman;Tamara V. Feldblyum;Michael T. Laub;Ian T. Paulsen

  • Rewiring the Specificity of Two-Component Signal Transduction Systems

    Jeffrey M. Skerker;Barrett S. Perchuk;Albert Siryaporn;Emma A. Lubin

  • Two-component signal transduction pathways regulating growth and cell cycle progression in a bacterium: a system-level analysis

    Jeffrey M Skerker;Melanie S Prasol;Barrett S Perchuk;Emanuele G Biondi

  • Genes directly controlled by CtrA, a master regulator of the Caulobacter cell cycle

    Michael T. Laub;Swaine L. Chen;Lucy Shapiro;Harley H. McAdams

  • Regulation of the bacterial cell cycle by an integrated genetic circuit

    Emanuele G. Biondi;Emanuele G. Biondi;Sarah J. Reisinger;Jeffrey M. Skerker;Jeffrey M. Skerker;Muhammad Arif

  • Bacillus subtilis SMC complexes juxtapose chromosome arms as they travel from origin to terminus.

    Xindan Wang;Hugo B. Brandão;Tung B. K. Le;Michael T. Laub

  • Bacterial Chromosome Organization and Segregation

    Anjana Badrinarayanan;Tung B.K. Le;Michael T. Laub

  • Permanent genetic memory with >1-byte capacity.

    Lei Yang;Alec A K Nielsen;Jesus Fernandez-Rodriguez;Conor J McClune

  • Evolving New Protein-Protein Interaction Specificity through Promiscuous Intermediates.

    Christopher D. Aakre;Julien Herrou;Tuyen N. Phung;Barrett S. Perchuk

  • Condensin promotes the juxtaposition of DNA flanking its loading site in Bacillus subtilis.

    Xindan Wang;Tung B.K. Le;Bryan R. Lajoie;Job Dekker

  • A Bacterial Toxin Inhibits DNA Replication Elongation through a Direct Interaction with the β Sliding Clamp

    Christopher D. Aakre;Tuyen N. Phung;David Huang;Michael T. Laub

  • Cell-cycle progression and the generation of asymmetry in Caulobacter crescentus

    Jeffrey M. Skerker;Michael T. Laub

  • Pervasive degeneracy and epistasis in a protein-protein interface

    Anna I. Podgornaia;Michael T. Laub

  • A Molecular Network That Produces Spontaneous Oscillations in Excitable Cells of Dictyostelium

    Michael T. Laub;William F. Loomis

  • Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA.

    Kristina Jonas;Jing Liu;Peter Chien;Michael T. Laub

Frequent Co-Authors

Lucy Shapiro
Lucy Shapiro Stanford University
Mark Goulian
Mark Goulian University of Pennsylvania
Harley H. McAdams
Harley H. McAdams Stanford University
Deborah A. Hogan
Deborah A. Hogan Dartmouth College
Casey S. Greene
Casey S. Greene University of Colorado Denver
William F. Loomis
William F. Loomis University of California, San Diego
Kerwyn Casey Huang
Kerwyn Casey Huang Stanford University
Urs Jenal
Urs Jenal University of Basel
George M. Church
George M. Church Harvard University

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