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Molecular Biology
Singapore
2026
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Genetics and Molecular Biology
Singapore
2024

D-Index & Metrics

Genetics

D-Index
93
Citations
39581
World Ranking
963
National Ranking
5

Molecular Biology

D-Index
93
Citations
39581
World Ranking
669
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Singapore Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Singapore Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Singapore Leader Award
  • 1990 - J. L. Lush Award in Animal Breeding, American Dairy Science Association
  • 1990 - The Rockefeller Prentice Memorial Award in Animal Breeding and Genetics, American Society of Animal Science

Overview

Brian K. Kennedy is affiliated with the National University of Singapore in Singapore. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with significant contributions in medicine as well. The main fields of study encompass:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, the subfields of study include:

  • Molecular Biology
  • Physiology
  • Aging
  • Geriatrics and Gerontology
  • Pediatrics, Perinatology and Child Health

Their academic work extensively covers topics such as:

  • Genetics, Aging, and Longevity in Model Organisms
  • Dietary Effects on Health
  • Epigenetics and DNA Methylation
  • Diet and Metabolism Studies
  • Adipose Tissue and Metabolism
  • Nutrition and Health in Aging
  • Mitochondrial Function and Pathology

Brian K. Kennedy has contributed multiple publications over the years. Some recent papers include:

  • Validation of biomarkers of aging, 2024, Nature Medicine
  • Biomarkers of aging for the identification and evaluation of longevity interventions, 2023, Cell
  • Taurine deficiency as a driver of aging, 2023, Science
  • The quest to slow ageing through drug discovery, 2020, Nature Reviews Drug Discovery
  • Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice, 2020, Cell Metabolism

Frequently publishing in specific venues, their work is often found in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Aging
  • Cell Metabolism
  • GeroScience
  • eLife

Collaboration is a significant aspect of their research, with frequent coauthors including:

  • Andrea B. Maier
  • Jan Gruber
  • Maximilian Unfried
  • Matt Kaeberlein
  • Luigi Ferrucci

The scientist has been recognized through awards such as:

  • The Rockefeller Prentice Memorial Award in Animal Breeding and Genetics, American Society of Animal Science (1990)
  • J. L. Lush Award in Animal Breeding, American Dairy Science Association (1990)

Best Publications

  • Geroscience: Linking Aging to Chronic Disease

    Brian K. Kennedy;Shelley L. Berger;Anne Brunet;Judith Campisi;Judith Campisi

  • Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients

    Matt Kaeberlein;R. Wilson Powers;Kristan K. Steffen;Eric A. Westman

  • Cellular senescence promotes adverse effects of chemotherapy and cancer relapse

    Marco Demaria;Marco Demaria;Monique N. O'Leary;Jianhui Chang;Lijian Shao

  • Extension of chronological life span in yeast by decreased TOR pathway signaling

    R. Wilson Powers;Matt Kaeberlein;Seth D. Caldwell;Brian K. Kennedy

  • MECHANISM OF INHIBITION OF PROTEIN-TYROSINE PHOSPHATASES BY VANADATE AND PERVANADATE

    Gregory Huyer;Susana Liu;John Kelly;Jason Moffat

  • Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population

    Morgan E. Levine;Jorge A. Suarez;Sebastian Brandhorst;Priya Balasubramanian

  • Substrate-specific Activation of Sirtuins by Resveratrol

    Matt Kaeberlein;Thomas McDonagh;Birgit Heltweg;Jeffrey Hixon

  • A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan

    Sebastian Brandhorst;In Young Choi;Min Wei;Chia Wei Cheng

  • Sirtuins in Aging and Age-Related Disease

    Valter D. Longo;Brian K. Kennedy

  • Histone H4 lysine-16 acetylation regulates cellular lifespan

    Weiwei Dang;Kristan K. Steffen;Rocco Perry;Jean A. Dorsey

  • Replicative and Chronological Aging in Saccharomyces cerevisiae

    Valter D. Longo;Gerald S. Shadel;Matt Kaeberlein;Matt Kaeberlein;Brian Kennedy;Brian Kennedy

  • Interventions to Slow Aging in Humans: Are We Ready?

    Valter D. Longo;Adam Antebi;Andrzej Bartke;Nir Barzilai

  • NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription.

    Jiyong Zhao;Jiyong Zhao;Brian K. Kennedy;Brandon D. Lawrence;David A. Barbie

  • Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae.

    Brian K Kennedy;Nicanor R Austriaco;Jisi Zhang;Leonard Guarente

  • Sir2-Independent Life Span Extension by Calorie Restriction in Yeast

    Matt Kaeberlein;Kathryn T Kirkland;Stanley Fields;Brian K Kennedy

  • The mechanistic Target of Rapamycin: The grand conducTOR of metabolism and aging

    Brian K. Kennedy;Dudley W. Lamming

  • LMNA mutations in atypical Werner's syndrome

    Lishan Chen;Lin Lee;Brian A Kudlow;Heloisa G Dos Santos

  • Yeast Life Span Extension by Depletion of 60S Ribosomal Subunits Is Mediated by Gcn4

    Kristan K. Steffen;Vivian L. MacKay;Emily O. Kerr;Mitsuhiro Tsuchiya

  • Redistribution of Silencing Proteins from Telomeres to the Nucleolus Is Associated with Extension of Life Span in S. cerevisiae

    Brian K Kennedy;Monica Gotta;David A Sinclair;Kevin Mills

  • Progeria syndromes and ageing: what is the connection?

    Christopher R. Burtner;Brian K. Kennedy;Brian K. Kennedy;Brian K. Kennedy

Frequent Co-Authors

Matt Kaeberlein
Matt Kaeberlein University of Washington
Yousin Suh
Yousin Suh Columbia University
Stanley Fields
Stanley Fields University of Washington
Luigi Fontana
Luigi Fontana University of Sydney
Ed Harlow
Ed Harlow Harvard University
Valter D. Longo
Valter D. Longo University of Southern California
Shelley L. Berger
Shelley L. Berger University of Pennsylvania
Daniel B. Carr
Daniel B. Carr Tufts University
Judith Campisi
Judith Campisi Buck Institute for Research on Aging

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