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Genetics

D-Index
64
Citations
26620
World Ranking
2748
National Ranking
1208

Overview

Junko Oshima is affiliated with the University of Washington in the United States. The research portfolio primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a total of 63 publications, and Medicine, covering 18 publications. Within these disciplines, key subfields include Molecular Biology, Physiology, Aging, Genetics, and Immunology.

The scientist's work focuses on various topics related to cellular and molecular biology. Notable areas of study include Nuclear Structure and Function, DNA Repair Mechanisms, Telomeres, Telomerase, and Senescence, Genetics, Aging, and Longevity in Model Organisms, RNA Research and Splicing, Genomics and Chromatin Dynamics, as well as Epigenetics and DNA Methylation.

Among the recent papers, notable publications include:

  • "TNF-α/IFN-γ synergy amplifies senescence-associated inflammation and SARS-CoV-2 receptor expression via hyper-activated JAK/STAT1," 2022, Aging Cell
  • "DNA methylation signatures in Blood DNA of Hutchinson-Gilford Progeria syndrome," 2022, Aging Cell
  • "Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex," 2023, Aging
  • "Targeted long-read sequencing identifies missing pathogenic variants in unsolved Werner syndrome cases," 2022, Journal of Medical Genetics
  • "SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome-the Myhre syndrome," 2021, GeroScience

The frequent co-authors who have collaborated extensively with Junko Oshima include:

  • George M. Martin (10 joint works)
  • Renuka Kandhaya-Pillai (6 joint works)
  • Fuki M. Hisama (6 joint works)
  • Yosra Bejaoui (5 joint works)
  • Nady El Hajj (5 joint works)

The scientist's contributions have appeared across several publication venues, including:

  • Aging (6 publications)
  • GeroScience (4 publications)
  • Aging Cell (3 publications)
  • The Journals of Gerontology Series A (3 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (3 publications)

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Candidate gene for the chromosome 1 familial Alzheimer's disease locus

    Ephrat Levy-Lahad;Wilma Wasco;Parvoneh Poorkaj;Donna M. Romano

  • Positional Cloning of the Werner's Syndrome Gene

    Chang En Yu;Junko Oshima;Ying Hui Fu;Ellen M. Wijsman

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The Werner syndrome protein is a DNA helicase.

    Matthew D. Gray;Jiang Cheng Shen;Ashwini S. Kamath-Loeb;A. Blank

  • Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies

    Steve Horvath;Junko Oshima;Junko Oshima;George M. Martin;Ake T. Lu

  • LMNA mutations in atypical Werner's syndrome

    Lishan Chen;Lin Lee;Brian A Kudlow;Heloisa G Dos Santos

  • Lessons from human progeroid syndromes

    George M. Martin;Junko Oshima

  • Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A.

    Jiang Cheng Shen;Matthew D. Gray;Junko Oshima;Lawrence A. Loeb

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Werner Syndrome Protein: I. DNA HELICASE AND DNA EXONUCLEASE RESIDE ON THE SAME POLYPEPTIDE *

    Jiang Cheng Shen;Matthew D. Gray;Junko Oshima;Ashwini S. Kamath-Loeb

  • Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventions

    Junko Oshima;Julia M. Sidorova;Raymond J. Monnat

  • The spectrum of WRN mutations in Werner syndrome patients

    Shurong Huang;Lin Lee;Nancy B. Hanson;Catherine Lenaerts

  • An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

    Charles E. Ogburn;Junko Oshima;Martin Poot;Ru Chen

  • Werner syndrome protein limits MYC-induced cellular senescence.

    Carla Grandori;Kou Juey Wu;Paula Fernandez;Celine Ngouenet

  • Mutations in the consensus helicase domains of the Werner syndrome gene

    C E Yu;J Oshima;E M Wijsman;J Nakura

  • Characterization of the human and mouse WRN 3'→5' exonuclease

    Shurong Huang;Sergey Beresten;Baomin Li;Junko Oshima

  • Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features

    Davor Lessel;Davor Lessel;Bruno Vaz;Swagata Halder;Swagata Halder;Paul J Lockhart

  • Werner Helicase Is Localized to Transcriptionally Active Nucleoli of Cycling Cells

    Matthew D. Gray;Lan Wang;Hagop Youssoufian;George M. Martin

  • LMNA mutations in atypical Werner's syndrome [5] (multiple letters)

    C. Vigouroux;F. Caux;J. Capeau;S. Christin-Maitre

Frequent Co-Authors

George M. Martin
George M. Martin University of Washington
Gerard D. Schellenberg
Gerard D. Schellenberg University of Pennsylvania
Christian Kubisch
Christian Kubisch Universität Hamburg
Chang En Yu
Chang En Yu University of Washington
Martin Poot
Martin Poot University of Würzburg
Raymond J. Monnat
Raymond J. Monnat University of Washington
Ying-Hui Fu
Ying-Hui Fu University of California, San Francisco
Ellen M. Wijsman
Ellen M. Wijsman University of Washington
Evelina Gatti
Evelina Gatti Aix-Marseille University
Judith Campisi
Judith Campisi Buck Institute for Research on Aging

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