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Microbiology

D-Index
85
Citations
22914
World Ranking
889
National Ranking
412

Overview

Jianhua Yu is affiliated with the City Of Hope National Medical Center in the United States. Their research primarily spans the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. The scientist's work encompasses several subfields, including Immunology, Molecular Biology, Oncology, Infectious Diseases, and Genetics.

Their research topics cover a diverse range of areas with particular focus on Immune Cell Function and Interaction, CAR-T cell therapy research, RNA modifications and cancer, IL-33, ST2, and ILC Pathways, Virus-based gene therapy research, SARS-CoV-2 and COVID-19 Research, and Nanoplatforms for cancer theranostics.

Jianhua Yu has published multiple papers in frequent venues such as Cancer Research, Nature Communications, Blood, bioRxiv (Cold Spring Harbor Laboratory), and The Journal of Immunology. Some recent papers include:

  • The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation, 2020, Nucleic Acids Research
  • The emerging field of oncolytic virus-based cancer immunotherapy, 2022, Trends in cancer
  • Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses, 2021, Cell Reports Medicine
  • Targeting the RNA m6A modification for cancer immunotherapy, 2022, Molecular Cancer
  • The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity, 2021, The Journal of Experimental Medicine

The scientist frequently collaborates with co-authors such as Michael A. Caligiuri, Jianying Zhang, Li-Shu Wang, Lei Tian, and Shoubao Ma, indicating a strong network within the scientific community focusing on similar research themes.

Best Publications

  • MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

    Ramiro Garzon;Shujun Liu;Muller Fabbri;Zhongfa Liu

  • The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti–PD-1 antibody

    Don M. Benson;Courtney E. Bakan;Anjali Mishra;Craig C. Hofmeister

  • Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver

    Shu Hao Hsu;Bo Wang;Janaiah Kota;Jianhua Yu

  • The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation.

    Tao Liu;Qinglv Wei;Jing Jin;Qingya Luo

  • The Broad Spectrum of Human Natural Killer Cell Diversity.

    Aharon G. Freud;Bethany L. Mundy-Bosse;Jianhua Yu;Michael A. Caligiuri

  • CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma

    Jianhong Chu;Youcai Deng;Don M. Benson;Shun He

  • Location and cellular stages of natural killer cell development.

    Jianhua Yu;Aharon G. Freud;Michael A. Caligiuri

  • Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses.

    Giulia Fulci;Laura Breymann;Davide Gianni;Kazuhiko Kurozomi

  • First-in-man clinical trial of CAR NK-92 cells: safety test of CD33-CAR NK-92 cells in patients with relapsed and refractory acute myeloid leukemia.

    Xiaowen Tang;Lin Yang;Zheng Li;Ansel P Nalin

  • Curcumin is a potent DNA hypomethylation agent.

    Zhongfa Liu;Zhiliang Xie;William Jones;Ryan E. Pavlovicz

  • CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells.

    Jianfeng Han;Jianhong Chu;Wing Keung Chan;Jianying Zhang

  • Elotuzumab directly enhances NK cell cytotoxicity against myeloma via CS1 ligation: evidence for augmented NK cell function complementing ADCC

    Shauna M. Collins;Courtney E. Bakan;Gina D. Swartzel;Craig C. Hofmeister

  • Pro- and Antiinflammatory Cytokine Signaling: Reciprocal Antagonism Regulates Interferon-gamma Production by Human Natural Killer Cells

    Jianhua Yu;Min Wei;Brian Becknell;Rossana Trotta

  • The Mechanism of Anti-PD-L1 Antibody Efficacy against PD-L1-Negative Tumors Identifies NK Cells Expressing PD-L1 as a Cytolytic Effector.

    Wenjuan Dong;Xiaojin Wu;Xiaojin Wu;Shoubao Ma;Shoubao Ma;Yufeng Wang

  • Targeted production of reactive oxygen species in mitochondria to overcome cancer drug resistance.

    Hai Wang;Zan Gao;Xuanyou Liu;Pranay Agarwal

  • CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets

    Jianhua Yu;Hsiaoyin Charlene Mao;Min Wei;Tiffany Hughes

  • Sp1/NFκB/HDAC/miR-29b Regulatory Network in KIT-Driven Myeloid Leukemia

    Shujun Liu;Lai Chu Wu;Jiuxia Pang;Ramasamy Santhanam

  • TGF-β Utilizes SMAD3 to Inhibit CD16-Mediated IFN-γ Production and Antibody-Dependent Cellular Cytotoxicity in Human NK Cells

    Rossana Trotta;Jessica Dal Col;Jianhua Yu;David Ciarlariello

  • Chitosan-Decorated Doxorubicin-Encapsulated Nanoparticle Targets and Eliminates Tumor Reinitiating Cancer Stem-like Cells

    Wei Rao;Hai Wang;Jianfeng Han;Shuting Zhao

  • Hyaluronic acid-decorated dual responsive nanoparticles of Pluronic F127, PLGA, and chitosan for targeted co-delivery of doxorubicin and irinotecan to eliminate cancer stem-like cells.

    Hai Wang;Pranay Agarwal;Shuting Zhao;Ronald X. Xu

  • Interleukin-1β Selectively Expands and Sustains Interleukin-22+ Immature Human Natural Killer Cells in Secondary Lymphoid Tissue

    Tiffany Hughes;Brian Becknell;Aharon G. Freud;Susan McClory

Frequent Co-Authors

Michael A. Caligiuri
Michael A. Caligiuri City Of Hope National Medical Center
Balveen Kaur
Balveen Kaur Augusta University
Shujun Liu
Shujun Liu University of Minnesota
Don M. Benson
Don M. Benson The Ohio State University
Steven M. Devine
Steven M. Devine The Ohio State University
Guido Marcucci
Guido Marcucci City Of Hope National Medical Center
E. Antonio Chiocca
E. Antonio Chiocca Brigham and Women's Hospital
Xiongbin Lu
Xiongbin Lu Indiana University
Yong Peng
Yong Peng Sichuan University
John C. Byrd
John C. Byrd University of Pittsburgh Cancer Institute

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Related Online Degrees & Career Pathways

Studying Microbiology in the USA opens doors to various healthcare and science-related careers. Many students explore complementary fields that blend medical knowledge with technology and patient care. For instance, becoming a functional medicine nurse practitioner involves advanced healthcare training and focuses on holistic patient treatment, which may interest those with a microbiology background.

Another growing field is medical coding. Professionals can pursue a career as a certified professional coder (CPC), a role essential for translating medical information into standardized codes for billing and records. This position demands attention to detail and precise knowledge of healthcare terminology.

For those drawn to data management, health information management job description and salary offers insight into careers focused on maintaining patient records and ensuring compliance with healthcare regulations. Many institutions now provide flexible online learning options.

Students interested in formal credentials can consider enrolling in a cahiim accredited him degree online, which prepares graduates for certification and leadership roles in health information management. Together, these pathways highlight the diverse opportunities available beyond traditional microbiology roles.

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