World's Best Scientists 2026 revealed!

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Medicine

D-Index
134
Citations
65341
World Ranking
2155
National Ranking
1217

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Guido Marcucci is affiliated with the City Of Hope National Medical Center in the United States. Their research spans multiple disciplines, primarily focusing on medicine and biochemistry, genetics, and molecular biology.

The scientist has published extensively in the field of hematology, contributing significantly to the understanding of leukemia and related disorders. Their work also intersects with molecular biology, public health, environmental and occupational health, oncology, and immunology.

Guido Marcucci's research topics cover a range of key areas including:

  • Acute Myeloid Leukemia Research
  • Acute Lymphoblastic Leukemia research
  • Chronic Myeloid Leukemia Treatments
  • Hematopoietic Stem Cell Transplantation
  • CAR-T cell therapy research
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Histone Deacetylase Inhibitors Research

Their recent papers include:

  • "Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion," 2020, Cancer Cell
  • "RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia," 2020, Cell Stem Cell
  • "R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis," 2021, Molecular Cell
  • "NCCN Guidelines Insights: Acute Myeloid Leukemia, Version 2.2021," 2021, Journal of the National Comprehensive Cancer Network
  • "The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia," 2022, Cancer Cell

Guido Marcucci has frequently collaborated with several coauthors, including:

  • Anthony S. Stein
  • Stephen J. Forman
  • Ibrahim Aldoss
  • Amandeep Salhotra
  • Ryotaro Nakamura

Publication venues where Guido Marcucci has contributed notably are:

  • Blood
  • Transplantation and Cellular Therapy
  • Leukemia
  • Clinical Lymphoma Myeloma & Leukemia
  • Leukemia & lymphoma/Leukemia and lymphoma

The scientist has also contributed to book publications, including:

  • "Biology and Treatment of Leukemia and Bone Marrow Neoplasms," published by Springer Science+Business Media in 2021

Guido Marcucci has been recognized as a Member of the Association of American Physicians.

Best Publications

  • Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

    Richard M. Stone;Sumithra J. Mandrekar;Ben L. Sanford;Kristina Laumann

  • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B.

    Muller Fabbri;Ramiro Garzon;Amelia Cimmino;Amelia Cimmino;Zhongfa Liu

  • Targeting microRNAs in cancer: rationale, strategies and challenges.

    Ramiro Garzon;Guido Marcucci;Carlo M. Croce

  • Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

    K. G. Roberts;Y. Li;D. Payne-Turner;R. C. Harvey

  • MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

    Ramiro Garzon;Shujun Liu;Muller Fabbri;Zhongfa Liu

  • R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

    Rui Su;Lei Dong;Chenying Li;Sigrid Nachtergaele

  • IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

    Guido Marcucci;Kati Maharry;Yue-Zhong Wu;Michael D. Radmacher

  • Adverse Prognostic Significance of KIT Mutations in Adult Acute Myeloid Leukemia With inv(16) and t(8;21): A Cancer and Leukemia Group B Study

    Peter Paschka;Guido Marcucci;Amy S. Ruppert;Krzysztof Mrózek

  • MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

    Ramiro Garzon;Stefano Volinia;Stefano Volinia;Chang-Gong Liu;Cecilia Fernandez-Cymering

  • METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification

    Hengyou Weng;Huilin Huang;Huizhe Wu;Xi Qin

  • Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?

    Krzysztof Mrózek;Guido Marcucci;Peter Paschka;Susan P. Whitman

  • Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications.

    Guido Marcucci;Torsten Haferlach;Hartmut Döhner

  • miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts

    Anna M. Eiring;Jason G. Harb;Paolo Neviani;Christopher Garton

  • Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

    Rongqing Pan;Leah J. Hogdal;Juliana M. Benito;Donna Bucci

  • MicroRNA fingerprints during human megakaryocytopoiesis

    Carlo M. Croce;Ramiro Garzon;George A. Calin

  • The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein

    Paolo Neviani;Ramasamy Santhanam;Rossana Trotta;Mario Notari

  • Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine

    William Blum;Ramiro Garzon;Rebecca B. Klisovic;Sebastian Schwind

  • Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

    Rui Su;Lei Dong;Yangchan Li;Min Gao

  • MicroRNA 29b functions in acute myeloid leukemia.

    Ramiro Garzon;Catherine E. A. Heaphy;Violaine Havelange;Muller Fabbri

  • Acute myeloid leukemia, version 3.2017: Clinical practice guidelines in oncology

    Margaret R. O'Donnell;Martin S. Tallman;Camille N. Abboud;Jessica K. Altman

Frequent Co-Authors

Clara D. Bloomfield
Clara D. Bloomfield The Ohio State University
Michael A. Caligiuri
Michael A. Caligiuri City Of Hope National Medical Center
John C. Byrd
John C. Byrd University of Pittsburgh Cancer Institute
Shujun Liu
Shujun Liu University of Minnesota
Richard A. Larson
Richard A. Larson University of Chicago
Susan P. Whitman
Susan P. Whitman The Ohio State University
Krzysztof Mrózek
Krzysztof Mrózek The Ohio State University
Bayard L. Powell
Bayard L. Powell Wake Forest University
Michael R. Grever
Michael R. Grever The Ohio State University
Jonathan E. Kolitz
Jonathan E. Kolitz Hofstra University

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