What is he best known for?
The fields of study he is best known for:
His main research concerns Cell biology, Apoptosis, Programmed cell death, Caspase and Genetics.
In the subject of general Cell biology, his work in Embryo is often linked to Pole plasm, thereby combining diverse domains of study.
His work carried out in the field of Apoptosis brings together such families of science as Regulation of gene expression, microRNA, Cytochrome c oxidase and Head involution.
His Programmed cell death study integrates concerns from other disciplines, such as Cancer research, Cell growth, Survivin, Cyclin-dependent kinase and Polo-like kinase.
In Caspase, Bruce A. Hay works on issues like Ectopic expression, which are connected to Cell, Mitogen-activated protein kinase and Tissue homeostasis.
His studies in Drosophila melanogaster integrate themes in fields like Genome, Gene family, Comparative genomics and Fungal protein.
His most cited work include:
- Comparative Genomics of the Eukaryotes (1459 citations)
- Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. (1345 citations)
- Expression of baculovirus P35 prevents cell death in Drosophila (912 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Genetics, Cell biology, Gene drive, Gene and Programmed cell death.
His study on Drosophila melanogaster, Germline, RNA interference and Genome is often connected to Mechanism as part of broader study in Genetics.
His Cell biology research incorporates themes from Inhibitor of apoptosis, Caspase, Apoptosis and Molecular biology.
His Apoptosis research includes themes of Cell, Function and Ectopic expression.
His Gene drive study combines topics from a wide range of disciplines, such as Cas9, Essential gene and Transgene.
Bruce A. Hay works mostly in the field of Programmed cell death, limiting it down to topics relating to Regulation of gene expression and, in certain cases, Phenotype.
He most often published in these fields:
- Genetics (42.31%)
- Cell biology (37.50%)
- Gene drive (29.81%)
What were the highlights of his more recent work (between 2016-2021)?
- Gene drive (29.81%)
- Genetics (42.31%)
- Computational biology (10.58%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Gene drive, Genetics, Computational biology, Gene and Cas9.
His Gene drive study also includes
- Essential gene, which have a strong connection to Cleave and Transgene,
- Ecology which connect with Homing.
His study brings together the fields of Threshold population and Genetics.
The concepts of his Computational biology study are interwoven with issues in Autophagy, Multicellular organism, Immunology and Gene delivery.
Cell biology is closely connected to Messenger RNA in his research, which is encompassed under the umbrella topic of Coding region.
His Cell biology study incorporates themes from Translational Activation, Untranslated region, Missense mutation, Disease and Regulation of gene expression.
Between 2016 and 2021, his most popular works were:
- Cleave and Rescue, a novel selfish genetic element and general strategy for gene drive (61 citations)
- Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs. (56 citations)
- Rules of the road for insect gene drive research and testing. (41 citations)
In his most recent research, the most cited papers focused on:
Bruce A. Hay mainly focuses on Gene drive, Genetics, CRISPR, Gene and Ploidy.
The study incorporates disciplines such as Melanogaster, Drosophila virilis, Drosophila melanogaster, Gene conversion and Essential gene in addition to Gene drive.
His Genetics research is multidisciplinary, relying on both Degenerative disease and Cell biology.
His biological study spans a wide range of topics, including Ecology, Malaria vector and Insect Gene.
His work in Homing endonuclease, Locus, Cas9, Marker gene and Transgene is related to Gene.
His research in Ploidy intersects with topics in Threshold population and Chromosomal translocation.
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