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Genetics

D-Index
60
Citations
30685
World Ranking
3101
National Ranking
1356

Overview

Bruce A. Hay is affiliated with the California Institute of Technology in the United States. Their research primarily focuses on areas within Biochemistry, Genetics, and Molecular Biology, with significant work in Agricultural and Biological Sciences. Their expertise encompasses several subfields including Molecular Biology, Insect Science, Genetics, Plant Science, and Epidemiology.

The scientist's work addresses a range of topics in genetic engineering and insect biology. Key subjects of research include:

  • CRISPR and Genetic Engineering
  • Insect symbiosis and bacterial influences
  • Evolution and Genetic Dynamics
  • Plant Virus Research Studies
  • Insect Resistance and Genetics
  • Mitochondrial Function and Pathology
  • Insect behavior and control techniques

Bruce A. Hay has contributed to a range of publications across several venues. Their recent papers include:

  • Engineering the Composition and Fate of Wild Populations with Gene Drive, 2020, Annual Review of Entomology
  • Gene drive and resilience through renewal with next generation Cleave and Rescue selfish genetic elements, 2020, Proceedings of the National Academy of Sciences
  • Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria, 2022, Nature Communications
  • Split versions of Cleave and Rescue selfish genetic elements for measured self limiting gene drive, 2021, PLoS Genetics
  • A drug-inducible sex-separation technique for insects, 2020, Nature Communications

The scientist frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • The biomedical & life sciences collection
  • Annual Review of Entomology

Collaborations have been a notable aspect of their career. Frequent co-authors include:

  • Georg Oberhofer
  • Tobin Ivy
  • Michelle L. Johnson
  • Ming Guo
  • Maciej Maselko

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.

    Ira E. Clark;Mark W. Dodson;Changan Jiang;Joseph H. Cao

  • Comparative Genomics of the Eukaryotes

    Gerald M. Rubin;Mark D. Yandell;Jennifer R. Wortman;George L. Gabor

  • The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

    Peizhang Xu;Stephanie Y. Vernooy;Ming Guo;Bruce A. Hay

  • Expression of baculovirus P35 prevents cell death in Drosophila

    Bruce A. Hay;Tanya Wolff;Gerald M. Rubin

  • Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death

    Bruce A. Hay;David A. Wassarman;Gerald M. Rubin

  • A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicases

    Bruce Hay;Lily Yeh Jan;Yuh Nung Jan

  • The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

    Susan L Wang;Christine J Hawkins;Soon Ji Yoo;H.-Arno J Müller

  • MicroRNAs and the regulation of cell death.

    Peizhang Xu;Ming Guo;Bruce A. Hay

  • Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role.

    Jun R Huh;Ming Guo;Bruce A Hay

  • Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms

    Soon Ji Yoo;Jun R. Huh;Israel R. Muro;Hong Yu

  • A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila.

    Chun-Hong Chen;Haixia Huang;Catherine M. Ward;Jessica T. Su

  • Identification of a component of Drosophila polar granules

    Bruce A. Hay;Larry Ackerman;Sandra Barbel;Lily Y. Jan

  • The Drosophila Caspase DRONC Cleaves following Glutamate or Aspartate and Is Regulated by DIAP1, HID, and GRIM *

    Christine J. Hawkins;Soon Ji Yoo;Erin P. Peterson;Susan L. Wang

  • Cell proliferation and apoptosis.

    Ming Guo;Bruce A Hay

  • Localization of vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity

    Bruce Hay;Lily Yeh Jan;Yuh Nung Jan

  • The germ cell-less gene product: A posteriorly localized component necessary for germ cell development in Drosophila

    Thomas A. Jongens;Bruce Hay;Lily Yeh Jan;Yuh Nung Jan

  • Caspase-Dependent Cell Death in Drosophila

    Bruce A. Hay;Ming Guo

  • The role of cytochrome c in caspase activation in Drosophila melanogaster cells.

    Loretta Dorstyn;Stuart Read;Dimitrios Cakouros;Jun R. Huh

  • Inactivation of Both foxo and reaper Promotes Long-Term Adult Neurogenesis in Drosophila

    Sarah E. Siegrist;Najm S. Haque;Chun-Hong Chen;Chun-Hong Chen;Bruce A. Hay

Frequent Co-Authors

Omar S. Akbari
Omar S. Akbari University of California, San Diego
Gerald M. Rubin
Gerald M. Rubin Howard Hughes Medical Institute
Yigong Shi
Yigong Shi Westlake University
Yuh Nung Jan
Yuh Nung Jan University of California, San Francisco
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco
Nieng Yan
Nieng Yan Princeton University
Sharad Kumar
Sharad Kumar University of Adelaide
Daniel L. Alkon
Daniel L. Alkon West Virginia University
Vladimir N. Uversky
Vladimir N. Uversky University of South Florida
Iswar K. Hariharan
Iswar K. Hariharan University of California, Berkeley

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