World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
12571
World Ranking
13770
National Ranking
5828

Research.com Recognitions

  • 2002 - Fellow of Alfred P. Sloan Foundation

Overview

Bingwei Lu is affiliated with Stanford University in the United States and specializes in biochemistry, genetics, and molecular biology with a significant focus on medicine. Their research primarily explores molecular and cellular mechanisms underlying neurological and metabolic diseases.

The main fields of study associated with their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, Lu's subfields of study are:

  • Molecular Biology
  • Cell Biology
  • Neurology
  • Genetics
  • Physiology

The scientist's research addresses several key topics:

  • Mitochondrial Function and Pathology
  • Endoplasmic Reticulum Stress and Disease
  • RNA and protein synthesis mechanisms
  • Sirtuins and Resveratrol in Medicine
  • Amyotrophic Lateral Sclerosis Research
  • Alzheimer's disease research and treatments
  • ATP Synthase and ATPases Research

Recent papers authored or coauthored by Bingwei Lu include:

  • "Molecular mechanisms of oxidative stress in stroke and cancer," 2021, Brain Disorders
  • "Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD," 2020, Proceedings of the National Academy of Sciences
  • "Mechanisms Linking Mitochondrial Dysfunction and Proteostasis Failure," 2020, Trends in Cell Biology
  • "Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease," 2021, Acta Neuropathologica Communications
  • "Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD," 2020, Cell Reports

Lu frequently publishes in venues such as:

  • Proceedings of the National Academy of Sciences
  • Developmental Cell
  • Nature Communications
  • Journal of Biological Chemistry
  • Brain Disorders

Frequent collaborators include:

  • Suman Rimal
  • Shuangxi Li
  • Ji Geng
  • Vishal Chavda
  • Ishaq Tantray

Bingwei Lu received the title of Fellow of the Alfred P. Sloan Foundation in 2002.

Best Publications

  • Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

    Yufeng Yang;Stephan Gehrke;Yuzuru Imai;Zhinong Huang

  • Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

    Yufeng Yang;Yingshi Ouyang;Lichuan Yang;M. Flint Beal

  • Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila.

    Yuzuru Imai;Stephan Gehrke;Hua Qin Wang;Ryosuke Takahashi

  • Parkin Suppresses Dopaminergic Neuron-Selective Neurotoxicity Induced by Pael-R in Drosophila

    Yufeng Yang;Isao Nishimura;Yuzuru Imai;Ryosuke Takahashi

  • Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression

    Stephan Gehrke;Yuzuru Imai;Nicholas Sokol;Bingwei Lu

  • Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

    Yufeng Yang;Stephan Gehrke;Md. Emdadul Haque;Yuzuru Imai

  • PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila.

    Isao Nishimura;Yufeng Yang;Bingwei Lu

  • Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria

    Song Liu;Tomoyo Sawada;Seongsoo Lee;Wendou Yu

  • Adherens junctions inhibit asymmetric division in the Drosophila epithelium

    Bingwei Lu;Fabrice Roegiers;Lily Y. Jan;Yuh Nung Jan

  • PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling

    Tian-Qiang Sun;Bingwei Lu;Jia-Jia Feng;Christoph Reinhard

  • Drosophila models of neurodegenerative diseases.

    Bingwei Lu;Hannes Vogel

  • NGF gene expression in actively growing brain glia

    B Lu;M Yokoyama;CF Dreyfus;IB Black

  • Partner of Numb Colocalizes with Numb during Mitosis and Directs Numb Asymmetric Localization in Drosophila Neural and Muscle Progenitors

    Bingwei Lu;Michael Rothenberg;Lily Y Jan;Yuh Nung Jan

  • The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons

    Wendou Yu;Yaping Sun;Su Guo;Bingwei Lu

  • Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon

    Hongyan Wang;Yingshi Ouyang;W. Gregory Somers;William Chia

  • Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease

    Katerina Venderova;Ghassan Kabbach;Elizabeth Abdel-Messih;Yi Zhang

  • HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites

    Chad A. Dickey;Judith Dunmore;Bingwei Lu;Ji Wu Wang

  • PINK1 and Parkin Control Localized Translation of Respiratory Chain Component mRNAs on Mitochondria Outer Membrane

    Stephan Gehrke;Zhihao Wu;Michael Klinkenberg;Yaping Sun

  • Altered ER–mitochondria contact impacts mitochondria calcium homeostasis and contributes to neurodegeneration in vivo in disease models

    Kyu-Sun Lee;Sungun Huh;Seongsoo Lee;Seongsoo Lee;Zhihao Wu

  • Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission

    Wencheng Liu;Rebeca Acín-Peréz;Kindiya D. Geghman;Giovanni Manfredi

Frequent Co-Authors

Yuh Nung Jan
Yuh Nung Jan University of California, San Francisco
Ryosuke Takahashi
Ryosuke Takahashi Kyoto University
Hannes Vogel
Hannes Vogel Stanford University
Maureen R. Hanson
Maureen R. Hanson Cornell University
Lily Yeh Jan
Lily Yeh Jan University of California, San Francisco
Su Guo
Su Guo University of California, San Francisco
Lewis T. Williams
Lewis T. Williams University of California, San Francisco
M. Flint Beal
M. Flint Beal Cornell University
Georg Auburger
Georg Auburger Goethe University Frankfurt
Michael Snyder
Michael Snyder Stanford University

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