Patrick A. Lewis

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

  Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  10661
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  8488
  Citations

• Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

  Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron

  2354
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  895
  Citations

• Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.

  Elisa Greggio;Shushant Jain;Ann Kingsbury;Rina Bandopadhyay

  833
  Citations

• Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences.

  Claudia Manzoni;Demis A Kia;Jana Vandrovcova;John Hardy

  687
  Citations

• Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

  Michael J. Devine;Mina Ryten;Petr Vodicka;Alison J. Thomson

  517
  Citations

• α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?

  Aoife P. Kiely;Yasmine T. Asi;Eleanna Kara;Patricia Limousin;Patricia Limousin

  504
  Citations

• The Parkinson Disease-associated Leucine-rich Repeat Kinase 2 (LRRK2) Is a Dimer That Undergoes Intramolecular Autophosphorylation

  Elisa Greggio;Ibardo Zambrano;Alice Kaganovich;Alexandra Beilina

  386
  Citations

• The R1441C mutation of LRRK2 disrupts GTP hydrolysis.

  Patrick A. Lewis;Elisa Greggio;Alexandra Beilina;Shushant Jain

  355
  Citations

• The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy

  Victoria S Burchell;David E Nelson;Alvaro Sanchez-Martinez;Alvaro Sanchez-Martinez;Marta Delgado-Camprubi

  336
  Citations

• Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  287
  Citations

• Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase

  Junpeng Deng;Patrick A. Lewis;Elisa Greggio;Eli Sluch

  279
  Citations

• The genetics of Parkinson's syndromes: a critical review.

  John Hardy;Patrick Lewis;Tamas Revesz;Andrew Lees

  270
  Citations

• DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress-response protein PRKRA

  Sarah Camargos;Sarah Camargos;Sonja Scholz;Javier Simón-Sánchez;Coro Paisán-Ruiz

  259
  Citations

• Genetic and phenotypic characterization of complex hereditary spastic paraplegia

  Eleanna Kara;Eleanna Kara;Arianna Tucci;Arianna Tucci;Claudia Manzoni;Claudia Manzoni;David S. Lynch

  209
  Citations

• Cancer and neurodegeneration: between the devil and the deep blue sea

  Hélène Plun-Favreau;Patrick A. Lewis;John Hardy;L. Miguel Martins

  184
  Citations

• Cell-free assays for gamma-secretase activity.

  Chris McLendon;TianPei Xin;Chewki Ziani-Cherif;M. Paul Murphy

  181
  Citations

• Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations

  Henry Houlden;Matt Baker;Eileen McGowan;Patrick Lewis

  173
  Citations

• Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study

  Alastair J Noyce;Alastair J Noyce;Demis A Kia;Gibran Hemani;Aude Nicolas

  171
  Citations