The scientist’s investigation covers issues in Protein structure, Biochemistry, Biophysics, G protein-coupled receptor and Stereochemistry. His biological study spans a wide range of topics, including Crystallography, Photoprotein, Aequorin and Active site. His studies in Biophysics integrate themes in fields like Transmembrane domain, Allosteric enzyme and Binding site.
Zhi-Jie Liu focuses mostly in the field of G protein-coupled receptor, narrowing it down to topics relating to Inverse agonist and, in certain cases, Rimonabant, Cannabinoid receptor type 2 and Pharmacology. His study in Stereochemistry is interdisciplinary in nature, drawing from both Aldehyde dehydrogenase and NAD+ kinase. His Antagonist research incorporates elements of Endocannabinoid system and Synthetic cannabinoids.
Biochemistry, Crystallography, Protein structure, Stereochemistry and Biophysics are his primary areas of study. His research in Crystallography intersects with topics in Crystallization, Aequorin and Photoprotein. His Protein structure study combines topics in areas such as Molecular biology and Transcription.
Zhi-Jie Liu has researched Stereochemistry in several fields, including Agonist, Aldehyde dehydrogenase, Hydrogen bond and Ligand. His work carried out in the field of Biophysics brings together such families of science as Receptor and G protein-coupled receptor. The study incorporates disciplines such as Inverse agonist, Antagonist, Point mutation, Transmembrane domain and Neuroscience in addition to G protein-coupled receptor.
His primary areas of study are G protein-coupled receptor, Receptor, Agonist, Computational biology and Cell biology. His G protein-coupled receptor research is multidisciplinary, incorporating perspectives in G protein, Cannabinoid receptor, Neuroscience, Allosteric regulation and Drug discovery. His Receptor study combines topics from a wide range of disciplines, such as Structural biology, Biophysics and Protein subunit.
His studies deal with areas such as Docking, Crystal structure and Peptide as well as Agonist. His study looks at the relationship between Cell biology and topics such as Ligand, which overlap with Stereochemistry, Mutation, Cholinergic and Virtual screening. He works mostly in the field of Stereochemistry, limiting it down to topics relating to Protease and, in certain cases, Transcription.
His scientific interests lie mostly in G protein-coupled receptor, Receptor, Computational biology, Drug discovery and Allosteric regulation. His G protein-coupled receptor research is multidisciplinary, relying on both Agonist and Biophysics. His biological study spans a wide range of topics, including Endogeny, Neuroscience, Endocannabinoid system and Docking.
His work deals with themes such as Pharmacology, Small molecule, Peptide and Cell biology, which intersect with Receptor. Zhi-Jie Liu combines subjects such as Dna encoding, Chemical synthesis and DNA with his study of Computational biology. The study incorporates disciplines such as Benzamidine, Structural biology, Inverse agonist and Biological evolution in addition to Drug discovery.
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Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Yan Gao;Yan Gao;Liming Yan;Yucen Huang;Fengjiang Liu.
Science (2020)
Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis
Atsushi Shimada;Hideaki Niwa;Kazuya Tsujita;Shiro Suetsugu;Shiro Suetsugu.
Cell (2007)
Crystal Structure of the Human Cannabinoid Receptor CB2.
Tian Hua;Kiran Vemuri;Mengchen Pu;Lu Qu;Lu Qu.
Cell (2016)
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response
Kislay Parvatiyar;Zhiqiang Zhang;Rosane M. Teles;Songying Ouyang.
Nature Immunology (2012)
Crystal structures of agonist-bound human cannabinoid receptor CB1
Tian Hua;Kiran Vemuri;Spyros P. Nikas;Robert B. Laprairie.
Nature (2017)
The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold.
Zhi-Jie Liu;Yuh-Ju Sun;John Rose;Yong-Je Chung.
Nature Structural & Molecular Biology (1997)
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
Quan Wang;Jiqin Wu;Haofeng Wang;Haofeng Wang;Yan Gao.
Cell (2020)
Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding
Songying Ouyang;Xianqiang Song;Yaya Wang;Heng Ru.
Immunity (2012)
Structure of the Ca2+-regulated photoprotein obelin at 1.7 A resolution determined directly from its sulfur substructure.
Zhi-Jie Liu;Eugene S. Vysotski;Chun-Jung Chen;John P. Rose.
Protein Science (2000)
NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING
Lu Zhang;Jinyao Mo;Karen V. Swanson;Haitao Wen.
Immunity (2014)
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