D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 48 Citations 9,751 195 World Ranking 14041 National Ranking 362

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Amino acid

The scientist’s investigation covers issues in Protein structure, Biochemistry, Biophysics, G protein-coupled receptor and Stereochemistry. His biological study spans a wide range of topics, including Crystallography, Photoprotein, Aequorin and Active site. His studies in Biophysics integrate themes in fields like Transmembrane domain, Allosteric enzyme and Binding site.

Zhi-Jie Liu focuses mostly in the field of G protein-coupled receptor, narrowing it down to topics relating to Inverse agonist and, in certain cases, Rimonabant, Cannabinoid receptor type 2 and Pharmacology. His study in Stereochemistry is interdisciplinary in nature, drawing from both Aldehyde dehydrogenase and NAD+ kinase. His Antagonist research incorporates elements of Endocannabinoid system and Synthetic cannabinoids.

His most cited work include:

  • Structure of the RNA-dependent RNA polymerase from COVID-19 virus. (517 citations)
  • Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis (324 citations)
  • Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase. (315 citations)

What are the main themes of his work throughout his whole career to date?

Biochemistry, Crystallography, Protein structure, Stereochemistry and Biophysics are his primary areas of study. His research in Crystallography intersects with topics in Crystallization, Aequorin and Photoprotein. His Protein structure study combines topics in areas such as Molecular biology and Transcription.

Zhi-Jie Liu has researched Stereochemistry in several fields, including Agonist, Aldehyde dehydrogenase, Hydrogen bond and Ligand. His work carried out in the field of Biophysics brings together such families of science as Receptor and G protein-coupled receptor. The study incorporates disciplines such as Inverse agonist, Antagonist, Point mutation, Transmembrane domain and Neuroscience in addition to G protein-coupled receptor.

He most often published in these fields:

  • Biochemistry (39.92%)
  • Crystallography (28.81%)
  • Protein structure (25.10%)

What were the highlights of his more recent work (between 2017-2021)?

  • G protein-coupled receptor (18.11%)
  • Receptor (15.23%)
  • Agonist (7.41%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are G protein-coupled receptor, Receptor, Agonist, Computational biology and Cell biology. His G protein-coupled receptor research is multidisciplinary, incorporating perspectives in G protein, Cannabinoid receptor, Neuroscience, Allosteric regulation and Drug discovery. His Receptor study combines topics from a wide range of disciplines, such as Structural biology, Biophysics and Protein subunit.

His studies deal with areas such as Docking, Crystal structure and Peptide as well as Agonist. His study looks at the relationship between Cell biology and topics such as Ligand, which overlap with Stereochemistry, Mutation, Cholinergic and Virtual screening. He works mostly in the field of Stereochemistry, limiting it down to topics relating to Protease and, in certain cases, Transcription.

Between 2017 and 2021, his most popular works were:

  • Structure of the RNA-dependent RNA polymerase from COVID-19 virus. (517 citations)
  • Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase. (315 citations)
  • 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. (90 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

His scientific interests lie mostly in G protein-coupled receptor, Receptor, Computational biology, Drug discovery and Allosteric regulation. His G protein-coupled receptor research is multidisciplinary, relying on both Agonist and Biophysics. His biological study spans a wide range of topics, including Endogeny, Neuroscience, Endocannabinoid system and Docking.

His work deals with themes such as Pharmacology, Small molecule, Peptide and Cell biology, which intersect with Receptor. Zhi-Jie Liu combines subjects such as Dna encoding, Chemical synthesis and DNA with his study of Computational biology. The study incorporates disciplines such as Benzamidine, Structural biology, Inverse agonist and Biological evolution in addition to Drug discovery.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure of the RNA-dependent RNA polymerase from COVID-19 virus.

Yan Gao;Yan Gao;Liming Yan;Yucen Huang;Fengjiang Liu.
Science (2020)

638 Citations

Curved EFC/F-BAR-Domain Dimers Are Joined End to End into a Filament for Membrane Invagination in Endocytosis

Atsushi Shimada;Hideaki Niwa;Kazuya Tsujita;Shiro Suetsugu;Shiro Suetsugu.
Cell (2007)

451 Citations

Crystal Structure of the Human Cannabinoid Receptor CB2.

Tian Hua;Kiran Vemuri;Mengchen Pu;Lu Qu;Lu Qu.
Cell (2016)

437 Citations

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response

Kislay Parvatiyar;Zhiqiang Zhang;Rosane M. Teles;Songying Ouyang.
Nature Immunology (2012)

376 Citations

Crystal structures of agonist-bound human cannabinoid receptor CB1

Tian Hua;Kiran Vemuri;Spyros P. Nikas;Robert B. Laprairie.
Nature (2017)

370 Citations

The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold.

Zhi-Jie Liu;Yuh-Ju Sun;John Rose;Yong-Je Chung.
Nature Structural & Molecular Biology (1997)

364 Citations

Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.

Quan Wang;Jiqin Wu;Haofeng Wang;Haofeng Wang;Yan Gao.
Cell (2020)

325 Citations

Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding

Songying Ouyang;Xianqiang Song;Yaya Wang;Heng Ru.
Immunity (2012)

271 Citations

Structure of the Ca2+-regulated photoprotein obelin at 1.7 A resolution determined directly from its sulfur substructure.

Zhi-Jie Liu;Eugene S. Vysotski;Chun-Jung Chen;John P. Rose.
Protein Science (2000)

245 Citations

NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING

Lu Zhang;Jinyao Mo;Karen V. Swanson;Haitao Wen.
Immunity (2014)

233 Citations

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