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Yoshihiro Oka

Yoshihiro Oka

D-Index & Metrics

Immunology

D-Index
58
Citations
11715
World Ranking
3528
National Ranking
140

Overview

Yoshihiro Oka is affiliated with Osaka University in Japan and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans diverse subfields including Molecular Biology, Immunology, Reproductive Medicine, Oncology, and Social Psychology.

The scientist's research extensively explores topics such as hypothalamic control of reproductive hormones, renal and related cancers, immunotherapy and immune responses, CAR-T cell therapy research, cancer immunotherapy and biomarkers, neuroendocrine regulation and behavior, and reproductive biology and its impacts on aquatic species.

Frequent coauthors collaborating with Yoshihiro Oka include Haruo Sugiyama, Yusuke Oji, Akihiro Tsuboi, Hiroko Nakajima, and Jun Nakata. Together, their work has been published in several scientific venues, with multiple articles appearing in Cancer Immunology Immunotherapy, bioRxiv (Cold Spring Harbor Laboratory), Current Medicinal Chemistry, ZOOLOGICAL SCIENCE, and Journal of Neuroendocrinology.

Selected recent papers authored by or involving Yoshihiro Oka include:

  • TMC4 is a novel chloride channel involved in high-concentration salt taste sensation (2021, The Journal of Physiological Sciences)
  • Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain (2022, Science Translational Medicine)
  • Multiple gonadotropin-releasing hormone systems in non-mammalian vertebrates: Ontogeny, anatomy, and physiology (2021, Journal of Neuroendocrinology)
  • Cellular and Humoral Immune Responses Induced by an HLA Class I-restricted Peptide Cancer Vaccine Targeting WT1 Are Associated With Favorable Clinical Outcomes in Advanced Ovarian Cancer (2021, Journal of Immunotherapy)
  • Estrogen upregulates the firing activity of hypothalamic gonadotropin-releasing hormone (GnRH1) neurons in the evening in female medaka (2022, Journal of Neuroendocrinology)

Best Publications

  • Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression

    Yoshihiro Oka;Akihiro Tsuboi;Tetsuya Taguchi;Tadashi Osaki

  • Aberrant Overexpression of the Wilms Tumor Gene (WT1) in Human Leukemia

    Kazushi Inoue;Hiroyasu Ogawa;Hiroyasu Ogawa;Yoshiaki Sonoda;Yoshiaki Sonoda;Takafumi Kimura;Takafumi Kimura

  • Induction of complete and molecular remissions in acute myeloid leukemia by Wilms’ tumor 1 antigen-targeted dendritic cell vaccination

    Viggo F. van Tendeloo;Ann Van de Velde;Ann van Driessche;Nathalie Cools

  • Human cytotoxic T-lymphocyte responses specific for peptides of the wild-type Wilms' tumor gene (WT1 ) product.

    Yoshihiro Oka;Olga A. Elisseeva;Akihiro Tsuboi;Hiroyasu Ogawa

  • Immunohistochemical detection of WT1 protein in a variety of cancer cells

    Shin-ichi Nakatsuka;Yusuke Oji;Tetsuya Horiuchi;Takayoshi Kanda

  • Cancer Immunotherapy Targeting Wilms’ Tumor Gene WT1 Product

    Yoshihiro Oka;Keiko Udaka;Akihiro Tsuboi;Olga A. Elisseeva

  • The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia.

    Hiroyasu Ogawa;Hiroya Tamaki;Kazuhiro Ikegame;Toshihiro Soma

  • Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers

    Yusuke Oji;Shinichiro Miyoshi;Hajime Maeda;Seiji Hayashi

  • Wilms' tumor gene (WT1) competes with differentiation-inducing signal in hematopoietic progenitor cells

    Kazushi Inoue;Hiroya Tamaki;Hiroyasu Ogawa;Yoshihiro Oka

  • Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia

    Sébastien Anguille;Ann L. Van De Velde;Evelien L. Smits;Viggo F. Van Tendeloo

  • Humoral immune responses against Wilms tumor gene WT1 product in patients with hematopoietic malignancies.

    Olga A. Elisseeva;Yoshihiro Oka;Akihiro Tsuboi;Kiyoyuki Ogata

  • Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma.

    Yusuke Oji;Shoji Nakamori;Masahiro Fujikawa;Shin-ichi Nakatsuka

  • Very low frequencies of human normal CD34+ haematopoietic progenitor cells express the Wilms' tumour gene WT1 at levels similar to those in leukaemia cells

    Naoki Hosen;Yoshiaki Sonoda;Yusuke Oji;Takafumi Kimura

  • Overexpression of the Wilms' tumor gene WT1 in primary astrocytic tumors

    Yusuke Oji;Tsuyoshi Suzuki;Yoko Nakano;Motohiko Maruno

  • The activated conformation of integrin β 7 is a novel multiple myeloma–specific target for CAR T cell therapy

    Naoki Hosen;Yukiko Matsunaga;Kana Hasegawa;Hiroshi Matsuno

  • Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer WT1 peptide modified at HLA-A*2402-binding residues.

    Akihiro Tsuboi;Yoshihiro Oka;Keiko Udaka;Masaki Murakami

  • Overexpression of the Wilms' tumor gene WT1 in colorectal adenocarcinoma

    Yusuke Oji;Hirofumi Yamamoto;Masaya Nomura;Yoko Nakano

  • AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

    Sumiyuki Nishida;Naoki Hosen;Toshiaki Shirakata;Keisuke Kanato

  • Wilms tumor gene peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis.

    Yoshihiro Oka;Akihiro Tsuboi;Masaki Murakami;Manabu Hirai

  • WT1 peptide vaccine for the treatment of cancer.

    Yoshihiro Oka;Akihiro Tsuboi;Yusuke Oji;Ichiro Kawase

  • Constitutive expression of the Wilms' tumor gene WT1 inhibits the differentiation of myeloid progenitor cells but promotes their proliferation in response to granulocyte-colony stimulating factor (G-CSF).

    Akihiro Tsuboi;Yoshihiro Oka;Hiroyasu Ogawa;Olga A Elisseeva

Frequent Co-Authors

Haruo Sugiyama
Haruo Sugiyama Osaka University
Yusuke Oji
Yusuke Oji Osaka University
Atsushi Kumanogoh
Atsushi Kumanogoh Osaka University
Katsuyuki Aozasa
Katsuyuki Aozasa Osaka University
Satoshi Morita
Satoshi Morita Kyoto University
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Masaki Yasukawa
Masaki Yasukawa Ehime University
Eiichi Morii
Eiichi Morii Osaka University
Shinzaburo Noguchi
Shinzaburo Noguchi Osaka University
Toshihisa Komori
Toshihisa Komori Nagasaki University

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