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Immunology

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90
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26995
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1083
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Medicine

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Overview

Richard J. O'Reilly is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research spans several interconnected fields within medicine, immunology, and hematology, focusing on areas critical to transplantation and immune system disorders.

The scientist's principal fields of study include Medicine and Immunology and Microbiology. Their work prominently addresses several subfields such as Hematology, Immunology, Oncology, Genetics, and Epidemiology. Within these domains, the main topics Richard J. O'Reilly explores are:

  • Hematopoietic Stem Cell Transplantation
  • Immunodeficiency and Autoimmune Disorders
  • CAR-T cell therapy research
  • Cytomegalovirus and herpesvirus research
  • Virus-based gene therapy research
  • Acute Lymphoblastic Leukemia research
  • Immune Cell Function and Interaction

Their recent scholarly output includes contributions to several high-impact journals. Notable recent papers are:

  • "Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors" (2021, Nature Cancer)
  • "The diagnosis of severe combined immunodeficiency (SCID): The Primary Immune Deficiency Treatment Consortium (PIDTC) 2022 Definitions" (2022, Journal of Allergy and Clinical Immunology)
  • "Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium" (2023, The Lancet)
  • "CD4+ T-cell reconstitution predicts survival outcomes after acute graft-versus-host-disease: a dual-center validation" (2020, Blood)
  • "Tabelecleucel for allogeneic haematopoietic stem-cell or solid organ transplant recipients with Epstein-Barr virus-positive post-transplant lymphoproliferative disease after failure of rituximab or rituximab and chemotherapy (ALLELE): a phase 3, multicentre, open-label trial" (2024, The Lancet Oncology)

Frequent publication venues for Richard J. O'Reilly's work include:

  • Transplantation and Cellular Therapy
  • Biology of Blood and Marrow Transplantation
  • Blood Advances
  • Blood
  • Journal of Allergy and Clinical Immunology

Collaboration is a significant aspect of their research career, with common co-authors being:

  • Susan E. Prockop
  • Jaap Jan Boelens
  • Andromachi Scaradavou
  • Nancy A. Kernan
  • Kevin J. Curran

Best Publications

  • Infusions of Donor Leukocytes to Treat Epstein-Barr Virus-Associated Lymphoproliferative Disorders after Allogeneic Bone Marrow Transplantation

    Esperanza B. Papadopoulos;Marc Ladanyi;David Emanuel;Stephen Mackinnon

  • Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

    David Lyden;Alison Z. Young;David Zagzag;Wei Yan

  • Transplantation Outcomes for Severe Combined Immunodeficiency, 2000–2009

    Sung Yun Pai;Brent R. Logan;Linda M. Griffith;Rebecca H. Buckley

  • Cytomegalovirus Pneumonia after Bone Marrow Transplantation Successfully Treated with the Combination of Ganciclovir and High-Dose Intravenous Immune Globulin

    David Emanuel;Isabel Cunningham;Kethy Jules-Elysee;Joel A. Brochstein

  • Effects of Recombinant Human Granulocyte Colony-Stimulating Factor on Neutropenia in Patients with Congenital Agranulocytosis

    Mary Ann Bonilla;Alfred P. Gillio;Mary Ruggeiro;Nancy A. Kernan

  • Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates.

    K. Welte;M. A. Bonilla;A. P. Gillio;T. C. Boone

  • Clonable T lymphocytes in T cell-depleted bone marrow transplants correlate with development of graft-v-host disease.

    Nancy A. Kernan;Nancy H. Collins;Lisa Juliano;Teresa Cartagena

  • Bone Marrow–Allograft Rejection by T Lymphocytes Recognizing a Single Amino Acid Difference in HLA-B44

    Katharina Fleischhauer;Nancy A. Kernan;Richard J. O'Reilly;Bo Dupont

  • Adoptive immunotherapy with unselected or EBV-specific T cells for biopsy-proven EBV+ lymphomas after allogeneic hematopoietic cell transplantation

    Ekaterina Doubrovina;Banu Oflaz-Sozmen;Susan E. Prockop;Nancy A. Kernan

  • Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma.

    Ekaterina S. Doubrovina;Mikhail M. Doubrovin;Elena Vider;Richard B. Sisson

  • Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts

    Carolyn A. Keever;Trudy N. Small;Neal Flomenberg;Glenn Heller

  • Establishing diagnostic criteria for severe combined immunodeficiency disease (SCID), leaky SCID, and Omenn syndrome: The Primary Immune Deficiency Treatment Consortium experience

    William T. Shearer;Elizabeth Dunn;Luigi D. Notarangelo;Christopher C. Dvorak

  • A phase 1/2 trial of arginine butyrate and ganciclovir in patients with Epstein-Barr virus-associated lymphoid malignancies.

    Susan P. Perrine;Olivier Hermine;Trudy Small;Felipe Suarez

  • Identification by HLA Typing of Intrauterine-Derived Maternal T Cells in Four Patients with Severe Combined Immunodeficiency

    Marilyn S. Pollack;Dahlia Kirkpatrick;Neena Kapoor;Bo Dupont

  • Allogeneic Bone Marrow Transplantation after Hyperfractionated Total-Body Irradiation and Cyclophosphamide in Children with Acute Leukemia

    Joel A. Brochstein;Nancy A. Kernan;Susan Groshen;Constance Cirrincione

  • Toxicity and response after CD19-specific CAR T-cell therapy in pediatric/young adult relapsed/refractory B-ALL

    Kevin J Curran;Kevin J Curran;Steven P Margossian;Steven P Margossian;Nancy A Kernan;Nancy A Kernan;Lewis B Silverman;Lewis B Silverman

  • The development of cellular immunity to Epstein-Barr virus after allogeneic bone marrow transplantation

    Kenneth G. Lucas;Trudy N. Small;Glenn Heller;Bo Dupont

  • Transfusion-Associated Acute Chagas Disease Acquired in the United States

    Irene H. Grant;Jonathan W.M. Gold;Murray Wittner;Herbert B. Tanowitz

  • Immune reconstitution and survival of 100 SCID patients post-hematopoietic cell transplant: a PIDTC natural history study.

    Jennifer Heimall;Brent R. Logan;Morton J. Cowan;Luigi D. Notarangelo

  • Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes.

    Guenther Koehne;Mikhail Doubrovin;Ekaterina Doubrovina;Pat Zanzonico

  • TLR1 and TLR6 Polymorphisms Are Associated with Susceptibility to Invasive Aspergillosis after Allogeneic Stem Cell Transplantation

    Sandra Kesh;Nana Yaa Mensah;Paolo Peterlongo;Dana Jaffe

Frequent Co-Authors

Nancy A. Kernan
Nancy A. Kernan Memorial Sloan Kettering Cancer Center
Sergio Giralt
Sergio Giralt Memorial Sloan Kettering Cancer Center
Miguel-Angel Perales
Miguel-Angel Perales Memorial Sloan Kettering Cancer Center
Marcel R.M. van den Brink
Marcel R.M. van den Brink Memorial Sloan Kettering Cancer Center
Glenn Heller
Glenn Heller Memorial Sloan Kettering Cancer Center
Katharine C. Hsu
Katharine C. Hsu Memorial Sloan Kettering Cancer Center
Michel Sadelain
Michel Sadelain Columbia University
Bo Dupont
Bo Dupont Memorial Sloan Kettering Cancer Center
Robert A. Good
Robert A. Good University of Minnesota
Donald B. Kohn
Donald B. Kohn University of California, Los Angeles

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