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2025

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  • 2025 - Research.com Best Scientists Award

Overview

Richard E. Champlin is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research focuses on medicine, with a strong emphasis on hematology and oncology. Over their career, they have contributed extensively to subfields such as hematology, oncology, immunology, molecular biology, and public health, environmental and occupational health.

Their scholarly output includes a significant number of publications across prominent topics in medical research. These include hematopoietic stem cell transplantation, acute myeloid leukemia research, CAR-T cell therapy research, acute lymphoblastic leukemia research, multiple myeloma research and treatments, immune cell function and interaction, and chronic myeloid leukemia treatments.

Richard E. Champlin has co-authored numerous studies with frequent collaborators including Elizabeth J. Shpall, Partow Kebriaei, Uday Popat, Amin M. Alousi, and Samer A. Srour. These partnerships have resulted in a substantial body of joint research work.

The scientist's publications are regularly featured in key medical journals and conference proceedings. Frequent publication venues for their work include Blood, Transplantation and Cellular Therapy, Blood Advances, American Journal of Hematology, and Bone Marrow Transplantation.

Some notable recent papers include:

  • Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors, 2020, New England Journal of Medicine
  • Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+ B cell tumors: a phase 1/2 trial, 2024, Nature Medicine
  • Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells, 2020, Blood
  • Indications for Hematopoietic Cell Transplantation and Immune Effector Cell Therapy: Guidelines from the American Society for Transplantation and Cellular Therapy, 2020, Biology of Blood and Marrow Transplantation
  • Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells, 2021, Journal of Clinical Investigation

Best Publications

  • Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors

    Enli Liu;David Marin;Pinaki Banerjee;Homer A. Macapinlac

  • Outcomes after transplantation of cord Blood or bone marrow from unrelated donors in adults with leukemia

    Mary J. Laughlin;Mary Eapen;Pablo Rubinstein;John E. Wagner

  • Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation.

    R H Collins;O Shpilberg;W R Drobyski;D L Porter

  • Engraftment of Allogeneic Hematopoietic Progenitor Cells With Purine Analog-Containing Chemotherapy: Harnessing Graft-Versus-Leukemia Without Myeloablative Therapy

    Sergio Giralt;Elihu Estey;Maher Albitar;Koen Van Besien

  • Transplant-lite: induction of graft-versus-malignancy using fludarabine-based nonablative chemotherapy and allogeneic blood progenitor-cell transplantation as treatment for lymphoid malignancies.

    I F Khouri;M Keating;M Körbling;D Przepiorka

  • Bone Marrow-derived Mesenchymal Stem Cells as Vehicles for Interferon-β Delivery into Tumors

    Matus Studeny;Frank C. Marini;Richard E. Champlin;Claudia Zompetta

  • Analysis of 462 transplantations from unrelated donors facilitated by the national marrow donor program

    Nancy A. Kernan;Glenn Bartsch;Robert C. Ash;Patrick G. Beatty

  • Mesenchymal Stem Cells: Potential Precursors for Tumor Stroma and Targeted-Delivery Vehicles for Anticancer Agents

    Matus Studeny;Frank C. Marini;Jennifer L. Dembinski;Claudia Zompetta

  • Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells.

    Martin Körbling;Ruth L. Katz;Abha Khanna;Arnout C. Ruifrok

  • Bone marrow transplantation for chronic myelogenous leukemia in chronic phase. Increased risk for relapse associated with T-cell depletion.

    John M. Goldman;Robert Peter Gale;Mary M. Horowitz;James C. Biggs

  • Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study

    Mary Eapen;Pablo Rubinstein;Mei Jie Zhang;Cladd Stevens

  • T-cell depletion of HLA-identical transplants in leukemia.

    AM Marmont;MM Horowitz;RP Gale;K Sobocinski

  • Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.

    Ernest S. Kawasaki;Steven S. Clark;Mazie Y. Coyne;Stephen D. Smith

  • Melphalan and purine analog–containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation

    Sergio Giralt;Peter F. Thall;Issa Khouri;Xuemei Wang

  • Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia

    Jeffrey J. Molldrem;Peter P. Lee;Changqing Wang;Kyrie Felio

  • Zygomycosis in a Tertiary-Care Cancer Center in the Era of Aspergillus-Active Antifungal Therapy: A Case-Control Observational Study of 27 Recent Cases

    Dimitrios P Kontoyiannis;Michail S. Lionakis;Russell E. Lewis;Russell E. Lewis;Georgios Chamilos

  • Treatment of Philadelphia chromosome–positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate

    Deborah A. Thomas;Stefan Faderl;Jorge Cortes;Susan O'Brien

  • Blood stem cells compared with bone marrow as a source of hematopoietic cells for allogeneic transplantation

    Richard E. Champlin;Norbert Schmitz;Mary M. Horowitz;Bernard Chapuis

  • Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML.

    Albert B. Deisseroth;Zhifei Zu;David Claxton;Elie G. Hanania

  • Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukaemia: a comparison study. Editorial comment

    Vanderson Rocha;Eliane Gluckman;Mary Eapen;Pablo Rubinstein

Frequent Co-Authors

Elizabeth J. Shpall
Elizabeth J. Shpall The University of Texas MD Anderson Cancer Center
Partow Kebriaei
Partow Kebriaei The University of Texas MD Anderson Cancer Center
Sergio Giralt
Sergio Giralt Memorial Sloan Kettering Cancer Center
Issa F. Khouri
Issa F. Khouri The University of Texas MD Anderson Cancer Center
Borje S. Andersson
Borje S. Andersson The University of Texas MD Anderson Cancer Center
Hagop M. Kantarjian
Hagop M. Kantarjian The University of Texas MD Anderson Cancer Center
Laurence J.N. Cooper
Laurence J.N. Cooper The University of Texas MD Anderson Cancer Center
Peter F. Thall
Peter F. Thall The University of Texas MD Anderson Cancer Center
Robert Z. Orlowski
Robert Z. Orlowski The University of Texas MD Anderson Cancer Center
Katayoun Rezvani
Katayoun Rezvani The University of Texas MD Anderson Cancer Center

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