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Psychology

D-Index
50
Citations
17118
World Ranking
5345
National Ranking
2923

Overview

John M. Hettema is affiliated with Virginia Commonwealth University in the United States. Their research spans psychology, biochemistry, genetics, and molecular biology, with a strong emphasis on clinical psychology, genetics, and experimental and cognitive psychology. They have contributed extensively to the subfields of cognitive neuroscience and psychiatry and mental health.

Their work frequently addresses topics related to child and adolescent psychosocial and emotional development, genetic associations and epidemiology, and anxiety, depression, psychometrics, treatment, and cognitive processes. Other topics include tryptophan and brain disorders, functional brain connectivity studies, BRCA gene mutations in cancer, and genomics and rare diseases.

Hettema's recent publications include:

  • Baseline brain function in the preadolescents of the ABCD Study, 2021, Nature Neuroscience
  • Rates of Incidental Findings in Brain Magnetic Resonance Imaging in Children, 2021, JAMA Neurology
  • Substance use patterns in 9-10 year olds: Baseline findings from the adolescent brain cognitive development (ABCD) study, 2021, Drug and Alcohol Dependence
  • An epigenome-wide association study of early-onset major depression in monozygotic twins, 2020, Translational Psychiatry
  • Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies, 2023, Molecular Psychiatry

They often collaborate with a group of frequent coauthors, including:

  • Roxann Roberson-Nay
  • Chelsea Sawyers
  • Brad Verhulst
  • Thalia C. Eley
  • James M. Bjork

Hettema publishes frequently in the following venues:

  • European Neuropsychopharmacology
  • Molecular Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biological Psychiatry
  • Journal of Psychiatric Research

Best Publications

  • A review and meta-analysis of the genetic epidemiology of anxiety disorders.

    John M. Hettema;Michael C. Neale;Kenneth S. Kendler

  • Childhood sexual abuse and adult psychiatric and substance use disorders in women: an epidemiological and cotwin control analysis

    Kenneth S. Kendler;Cynthia M. Bulik;Judy Silberg;John M. Hettema

  • Life event dimensions of loss, humiliation, entrapment, and danger in the prediction of onsets of major depression and generalized anxiety.

    Kenneth S. Kendler;John M. Hettema;Frank Butera;Charles O. Gardner

  • Image processing and analysis methods for the Adolescent Brain Cognitive Development Study.

    Donald J. Hagler;Sean N. Hatton;M. Daniela Cornejo;Carolina Makowski

  • A population-based twin study of the relationship between neuroticism and internalizing disorders.

    John M Hettema;Michael C Neale;John M Myers;Carol A Prescott

  • The structure of genetic and environmental risk factors for anxiety disorders in men and women.

    John M. Hettema;Carol A. Prescott;John M. Myers;Michael C. Neale

  • Meta-analysis of genome-wide association studies of anxiety disorders.

    T. Otowa;T. Otowa;K. Hek;M. Lee;E. M. Byrne;E. M. Byrne

  • Co-morbid major depression and generalized anxiety disorders in the National Comorbidity Survey follow-up

    Ronald C. Kessler;Michael Gruber;John M. Hettema;Irving Hwang

  • A major role for common genetic variation in anxiety disorders

    Kirstin L. Purves;Jonathan R. I. Coleman;Sandra M. Meier;Sandra M. Meier;Sandra M. Meier;Christopher Rayner

  • Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder

    Marleen H.M. De Moor;Stéphanie M. Van Den Berg;Karin J.H. Verweij;Karin J.H. Verweij;Robert F. Krueger

  • Genetic and environmental sources of covariation between generalized anxiety disorder and neuroticism.

    John M. Hettema;Carol A. Prescott;Kenneth S. Kendler

  • SIRT1 Activates MAO-A in the Brain to Mediate Anxiety and Exploratory Drive

    Sergiy Libert;Kelli Pointer;Eric L. Bell;Abhirup Das

  • Posttraumatic Stress Disorder: Clinical Features, Pathophysiology, and Treatment

    W. Victor R. Vieweg;Demetrios A. Julius;Demetrios A. Julius;Antony Fernandez;Antony Fernandez;Mary Beatty-Brooks

  • What is the genetic relationship between anxiety and depression

    John M. Hettema

  • Low extraversion and high neuroticism as indices of genetic and environmental risk for social phobia, agoraphobia, and animal phobia.

    O. Joseph Bienvenu;John M. Hettema;Michael C. Neale;Carol A. Prescott

  • A twin study of the genetics of fear conditioning.

    John M. Hettema;Peter Annas;Michael C. Neale;Kenneth S. Kendler

  • Association between glutamic acid decarboxylase genes and anxiety disorders, major depression, and neuroticism

    J M Hettema;S S An;M C Neale;J Bukszar

  • Physical similarity and the equal-environment assumption in twin studies of psychiatric disorders.

    John M. Hettema;Michael C. Neale;Kenneth S. Kendler

  • Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

    Stephanie M. van den Berg;Marleen H. M. de Moor;Karin J. H. Verweij;Karin J. H. Verweij;Robert F. Krueger

  • A whole genome association study of neuroticism using DNA pooling.

    S Shifman;A Bhomra;S Smiley;N R Wray

  • Citalopram, QTc Interval Prolongation, and Torsade de Pointes. How Should We Apply the Recent FDA Ruling?

    W. Victor R. Vieweg;Mehrul Hasnain;Robert H. Howland;John M. Hettema

  • Meta-Analysis of Genome-Wide Association Studies of Anxiety Disorders

    Nick Martin;Takeshi Otowa;Minyoung Lee;Catharina Hartman

Frequent Co-Authors

Michael C. Neale
Michael C. Neale Virginia Commonwealth University
Ellen Leibenluft
Ellen Leibenluft National Institutes of Health
Melissa A. Brotman
Melissa A. Brotman National Institutes of Health
Daniel S. Pine
Daniel S. Pine National Institutes of Health
Steven H. Aggen
Steven H. Aggen Virginia Commonwealth University
Carol A. Prescott
Carol A. Prescott University of Southern California
Dorret I. Boomsma
Dorret I. Boomsma Vrije Universiteit Amsterdam
Christel M. Middeldorp
Christel M. Middeldorp University of Queensland
William G. Iacono
William G. Iacono University of Minnesota
Grant W. Montgomery
Grant W. Montgomery University of Queensland

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