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Brenda W.J.H. Penninx

Brenda W.J.H. Penninx

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Best Scientists
2025
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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
216
Citations
184528
World Ranking
11
National Ranking
2

Best Scientists

D-Index
216
Citations
184528
World Ranking
159
National Ranking
4

Medicine

D-Index
220
Citations
192301
World Ranking
88
National Ranking
3

Research.com Recognitions

  • 2026 - Research.com Medicine in Netherlands Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in Netherlands Leader Award
  • 2023 - Research.com Medicine in Netherlands Leader Award
  • 2022 - Research.com Medicine in Netherlands Leader Award
  • 2020 - Member of the European Academy of Sciences
  • 2016 - Royal Netherlands Academy of Arts and Sciences

Overview

Brenda W.J.H. Penninx is affiliated with Amsterdam UMC in the Netherlands and has an extensive publication record primarily focused on psychology, medicine, and neuroscience. Their research spans several subfields including experimental and cognitive psychology, clinical psychology, biological psychiatry, cognitive neuroscience, and behavioral neuroscience.

The scientist's main research topics cover mental health research, tryptophan and brain disorders, stress responses and cortisol, functional brain connectivity studies, child and adolescent psychosocial and emotional development, treatment of major depression, and genetic associations and epidemiology.

Brenda W.J.H. Penninx has contributed to a range of frequent publication venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Affective Disorders
  • European Neuropsychopharmacology
  • Psychological Medicine
  • UNC Libraries

The scientist has collaborated extensively with others in the field, including:

  • Yuri Milaneschi (106 co-authored works)
  • Femke Lamers (90 co-authored works)
  • Dorret I. Boomsma (61 co-authored works)
  • Erik J. Giltay (52 co-authored works)
  • Christiaan H. Vinkers (40 co-authored works)

Some notable recent papers authored by or involving Brenda W.J.H. Penninx include:

  • "Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression," 2021, published in Nature Genetics
  • "The mental health impact of the COVID-19 pandemic on people with and without depressive, anxiety, or obsessive-compulsive disorders: a longitudinal study of three Dutch case-control cohorts," 2020, published in The Lancet Psychiatry
  • "Anxiety disorders," 2021, published in The Lancet
  • "Major depressive disorder," 2023, published in Nature Reviews Disease Primers
  • "Sleep characteristics across the lifespan in 1.1 million people from the Netherlands, United Kingdom and United States: a systematic review and meta-analysis," 2020, published in Nature Human Behaviour

Brenda W.J.H. Penninx is recognized by membership in the European Academy of Sciences since 2020 and the Royal Netherlands Academy of Arts and Sciences since 2016.

Best Publications

  • Overweight, Obesity, and Depression A Systematic Review and Meta-analysis of Longitudinal Studies

    Floriana S. Luppino;Leonore M. de Wit;Paul F. Bouvy;Theo Stijnen

  • Biological, clinical and population relevance of 95 loci for blood lipids

    Tanya M. Teslovich;Kiran Musunuru;Albert V. Smith;Andrew C. Edmondson

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    Elizabeth K. Speliotes;Elizabeth K. Speliotes;Cristen J. Willer;Sonja I. Berndt;Keri L. Monda

  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    Naomi R. Wray;Stephan Ripke;Stephan Ripke;Stephan Ripke;Manuel Mattheisen;MacIej Trzaskowski

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    Hana Lango Allen;Karol Estrada;Guillaume Lettre;Sonja I. Berndt

  • Major depressive disorder

    Christian Otte;Stefan M. Gold;Stefan M. Gold;Brenda W. Penninx;Carmine Maria Pariante

  • Integrative approaches for large-scale transcriptome-wide association studies.

    Alexander Gusev;Alexander Gusev;Arthur Ko;Huwenbo Shi;Gaurav Bhatia;Gaurav Bhatia

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

  • Depression and cardiac mortality: results from a community-based longitudinal study.

    Brenda W.J.H. Penninx;Aartjan T.F. Beekman;Adriaan Honig;Dorly J.H. Deeg

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Self-reports and general practitioner information on the presence of chronic diseases in community dwelling elderly. A study on the accuracy of patients' self-reports and on determinants of inaccuracy.

    Didi M.W. Kriegsman;Brenda W.J.H. Penninx;Jacques Th.M. Van Eijk;A.Joan P. Boeke

  • Inflammatory markers and onset of cardiovascular events: results from the Health ABC study.

    Matteo Cesari;Brenda W.J.H. Penninx;Anne B. Newman;Stephen B. Kritchevsky

  • Modulation of genetic associations with serum urate levels by body-mass-index in humans

    Jennifer E. Huffman;Eva Albrecht;Alexander Teumer;Massimo Mangino

  • Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

    E. K. Speliotes;C. J. Willer;S. I. Berndt;K. L. Monda

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

  • Hundreds of variants clustered in genomic loci and biological pathways affect human height

    H. Lango Allen;K. Estrada;G. Lettre;S. I. Berndt

Frequent Co-Authors

Dorret I. Boomsma
Dorret I. Boomsma Vrije Universiteit Amsterdam
Jouke-Jan Hottenga
Jouke-Jan Hottenga Hamad bin Khalifa University
Gonneke Willemsen
Gonneke Willemsen Vrije Universiteit Amsterdam
Nicholas G. Martin
Nicholas G. Martin QIMR Berghofer Medical Research Institute
Tonu Esko
Tonu Esko University of Tartu
Eco J. C. de Geus
Eco J. C. de Geus Vrije Universiteit Amsterdam
Aartjan T.F. Beekman
Aartjan T.F. Beekman Vrije Universiteit Amsterdam
Grant W. Montgomery
Grant W. Montgomery University of Queensland
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Olli T. Raitakari
Olli T. Raitakari Turku University Hospital

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