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Chemistry
Canada
2025

D-Index & Metrics

Chemistry

D-Index
82
Citations
24593
World Ranking
3080
National Ranking
68

Research.com Recognitions

  • 2025 - Research.com Chemistry in Canada Leader Award
  • 2022 - Research.com Chemistry in Canada Leader Award
  • 2010 - Fellow of the Royal Society of Canada Academy of Science
  • 2009 - Bioinorganic Chemistry Award, Royal Society of Chemistry (UK)

Overview

Chris Orvig is affiliated with the University of British Columbia in Canada. They have contributed extensively to research in the fields of Medicine and Materials Science, with a substantial focus on Materials Chemistry and Radiology, Nuclear Medicine, and Imaging. Their work spans various specialized subfields, including Inorganic Chemistry, Oncology, and Pulmonary and Respiratory Medicine.

Their research covers a diverse range of main topics, notably Radiopharmaceutical Chemistry and Applications, Crystallization and Solubility Studies, and X-ray Diffraction in Crystallography. Additional focal areas include the chemistry and processing of radioactive elements, Medical Imaging Techniques and Applications, Lanthanide and Transition Metal Complexes, and Monoclonal and Polyclonal Antibodies Research.

Chris Orvig's publication record features papers in several prominent scientific venues. These include:

  • The Cambridge Structural Database
  • Inorganic Chemistry
  • Nuclear Medicine and Biology
  • Dalton Transactions
  • Bioconjugate Chemistry

Frequent co-authors in their collaborations are:

  • María de Guadalupe Jaraquemada-Peláez
  • Brian O. Patrick
  • Luke Wharton
  • Lily Southcott
  • Valery Radchenko

Highlights from their recent research articles include:

  • "Harnessing α-Emitting Radionuclides for Therapy: Radiolabeling Method Review" (2021), published in Journal of Nuclear Medicine
  • "225Ac-H4py4pa for Targeted Alpha Therapy" (2020), published in Bioconjugate Chemistry
  • "Discovery of a Copper-Based Mcl-1 Inhibitor as an Effective Antitumor Agent" (2020), published in Journal of Medicinal Chemistry
  • "Recent Advances in Asialoglycoprotein Receptor and Glycyrrhetinic Acid Receptor-Mediated and/or pH-Responsive Hepatocellular Carcinoma- Targeted Drug Delivery" (2020), published in Current Medicinal Chemistry
  • "Glypican-3-Targeted 227Th α-Therapy Reduces Tumor Burden in an Orthotopic Xenograft Murine Model of Hepatocellular Carcinoma" (2021), published in Journal of Nuclear Medicine

Chris Orvig has been recognized with notable awards including the Fellowship of the Royal Society of Canada in 2010, under the Academy of Science, and the Bioinorganic Chemistry Award from the Royal Society of Chemistry (UK) in 2009.

Best Publications

  • Metallodrugs in Medicinal Inorganic Chemistry

    Katja Dralle Mjos;Chris Orvig

  • Matching chelators to radiometals for radiopharmaceuticals.

    Eric W. Price;Eric W. Price;Chris Orvig

  • Vanadium Compounds as Insulin Mimics

    Katherine H. Thompson;John H. McNeill;Chris Orvig

  • Medicinal inorganic chemistry: introduction.

    Chris Orvig;Michael J. Abrams

  • Biosorbents for hexavalent chromium elimination from industrial and municipal effluents

    Bidyut Saha;Bidyut Saha;Chris Orvig

  • Vanadium in diabetes: 100 years from Phase 0 to Phase I.

    Katherine H. Thompson;Chris Orvig

  • Vanadium treatment of type 2 diabetes: a view to the future.

    Katherine H. Thompson;Jay Lichter;Carl LeBel;Michael C. Scaife

  • Bis(maltolato)oxovanadium(IV) is a potent insulin mimic.

    John H. McNeill;V. G. Yuen;H. R. Hoveyda;Chris Orvig

  • Boon and bane of metal ions in medicine.

    Katherine H. Thompson;Chris Orvig

  • Radioactive Main Group and Rare Earth Metals for Imaging and Therapy

    Thomas I. Kostelnik;Chris Orvig

  • Medicinal inorganic chemistry approaches to passivation and removal of aberrant metal ions in disease.

    Lauren E. Scott;Chris Orvig

  • Design of targeting ligands in medicinal inorganic chemistry

    Tim Storr;Tim Storr;Katherine H. Thompson;Chris Orvig

  • Potentiometric, Calorimetric, and Solution NMR Studies of a Tridentate Ligand Which has a Marked Preference for Formation of Bis(ligand) versus Mono(ligand) Lanthanide Complexes and Which Exhibits High Selectivity for Heavier Lanthanides

    P. Caravan;Tomas Hedlund;Shuang Liu;c Staffan Sjoeberg

  • Reaction chemistry of BMOV, bis(maltolato)oxovanadium(IV), a potent insulin mimetic agent

    Chris Orvig;P. Caravan;Lucio Gelmini;Nicholas Glover

  • Synthesis and characterization of lanthanide [Ln(L)]2 complexes of N4O3 amine phenol ligands with phenolate oxygen bridges: evidence for very weak magnetic exchange between lanthanide ions

    Shuang Liu;Lucio Gelmini;Steven J. Rettig;Robert C. Thompson

  • Tumour targeting with radiometals for diagnosis and therapy.

    Caterina F Ramogida;Chris Orvig

  • Metal complexes in medicinal chemistry: new vistas and challenges in drug design

    Katherine H. Thompson;Chris Orvig

  • Cellular Transport Mechanisms of Cytotoxic Metallodrugs: An Overview beyond Cisplatin

    Sarah Spreckelmeyer;Chris Orvig;Angela Casini

  • Speciation of aluminum in biological systems.

    W. R. Harris;G. Berthon;J. P. Day;C. Exley

  • Synthesis and characterization of dual function vanadyl, gallium and indium curcumin complexes for medicinal applications.

    Khosro Mohammadi;Katherine H. Thompson;Brian O. Patrick;Tim Storr

  • A new class of oxotechnetium(5+) chelate complexes containing a TcON2S2 core

    Alan. Davison;Alun G. Jones;Chris. Orvig;Miriam. Sohn

Frequent Co-Authors

Steven J. Rettig
Steven J. Rettig University of British Columbia
Brian O. Patrick
Brian O. Patrick University of British Columbia
John H. McNeill
John H. McNeill University of British Columbia
Tim Storr
Tim Storr Simon Fraser University
Shuang Liu
Shuang Liu Purdue University West Lafayette
Zhen-Feng Chen
Zhen-Feng Chen Guangxi Normal University
Hong Liang
Hong Liang Guangxi Normal University
Peter Caravan
Peter Caravan Harvard University
Jason S. Lewis
Jason S. Lewis Memorial Sloan Kettering Cancer Center
Brian M. Zeglis
Brian M. Zeglis Hunter College

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