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Chemistry

D-Index
51
Citations
8308
World Ranking
14080
National Ranking
2188

Overview

Zhen-Feng Chen is affiliated with Guangxi Normal University in China and has established a significant presence in the field of materials science, with a particular emphasis on materials chemistry. Their research portfolio includes over 118 publications related to this main field, with substantial contributions to subfields such as materials chemistry, oncology, organic chemistry, molecular biology, and inorganic chemistry.

The scientist's research interests span multiple topics, including crystallization and solubility studies, X-ray diffraction in crystallography, synthesis and characterization of metal complexes, and nanoplatforms for cancer theranostics. Further exploration of synthesis and biological activity and investigations into metal-organic frameworks also form part of their academic work.

Zhen-Feng Chen has published research articles in various scholarly venues. Their more frequent publication outlets include:

  • The Cambridge Structural Database
  • Journal of Inorganic Biochemistry
  • Journal of Medicinal Chemistry
  • Dalton Transactions
  • European Journal of Medicinal Chemistry

Their recent research outputs, reflecting a focus on bioinorganic chemistry and cancer-related studies, include the following papers:

  • Copper(II) Complexes of Halogenated Quinoline Schiff Base Derivatives Enabled Cancer Therapy through Glutathione-Assisted Chemodynamic Therapy and Inhibition of Autophagy Flux, 2022, Journal of Medicinal Chemistry
  • New copper complexes inducing bimodal death through apoptosis and autophagy in A549 cancer cells, 2020, Journal of Inorganic Biochemistry
  • Bifunctional Naphthoquinone Aromatic Amide-Oxime Derivatives Exert Combined Immunotherapeutic and Antitumor Effects through Simultaneous Targeting of Indoleamine-2,3-dioxygenase and Signal Transducer and Activator of Transcription 3, 2020, Journal of Medicinal Chemistry
  • Terpyridine copper(ii) complexes as potential anticancer agents by inhibiting cell proliferation, blocking the cell cycle and inducing apoptosis in BEL-7402 cells, 2021, Dalton Transactions
  • Discovery of a Copper-Based Mcl-1 Inhibitor as an Effective Antitumor Agent, 2020, Journal of Medicinal Chemistry

Collaborative work features prominently in their research activities. Frequent coauthors who have contributed to multiple joint publications include Hong Liang, Wen-Ying Shen, Cheng Hou, and Chun-Peng Jia, evidencing consistent partnerships across diverse studies.

Best Publications

  • 2D molecular square grid with strong blue fluorescent emission: a complex of norfloxacin with zinc(II).

    Zhen-Feng Chen;Ren-Gen Xiong;Jing Zhang;Xue-Tai Chen

  • Label-free colorimetric aptasensor based on nicking enzyme assisted signal amplification and DNAzyme amplification for highly sensitive detection of protein.

    Yong Huang;Jia Chen;Shulin Zhao;Ming Shi

  • Stabilization of G-quadruplex DNA, inhibition of telomerase activity, and tumor cell apoptosis by organoplatinum(II) complexes with oxoisoaporphine.

    Zhen-Feng Chen;Qi-Pin Qin;Jiao-Lan Qin;Yan-Cheng Liu

  • Electrochemical sulfonylation of thiols with sulfonyl hydrazides: a metal- and oxidant-free protocol for the synthesis of thiosulfonates

    Zu-Yu Mo;Toreshettahally R. Swaroop;Wei Tong;Yu-Zhen Zhang

  • Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis

    Zhen-Feng Chen;Qi-Pin Qin;Jiao-Lan Qin;Jie Zhou

  • An unprecedented six-fold anion-type chiral diamondoid-like eight-coordinate Cd(II) coordination polymer with a second-order nonlinear optical effect

    Zhen-Feng Chen;Ren-Gen Xiong;Brendan F. Abrahams;Xiao-Zeng You

  • Samarium(III)-Catalyzed C(sp3)–H Bond Activation: Synthesis of Indolizines via C–C and C–N Coupling between 2-Alkylazaarenes and Propargylic Alcohols

    Xu Wang;Shen-yan Li;Ying-ming Pan;Heng-shan Wang

  • Organometallic Gold(III) Complexes Similar to Tetrahydroisoquinoline Induce ER-Stress-Mediated Apoptosis and Pro-Death Autophagy in A549 Cancer Cells

    Ke-Bin Huang;Feng-Yang Wang;Xiao-Ming Tang;Hai-Wen Feng

  • The antitumor activity of zinc(II) and copper(II) complexes with 5,7-dihalo-substituted-8-quinolinoline.

    Yan-Cheng Liu;Jian-Hua Wei;Zhen-Feng Chen;Mei Liu

  • In situ ligand synthesis and the first crystallographically characterized lanthanide 3-D pillared networks containing benzene-1,4-disulfonate as a building block

    Ren-Gen Xiong;Jing Zhang;Zhen-Feng Chen;Xiao-Zeng You

  • Studies on antitumor mechanism of two planar platinum(II) complexes with 8-hydroxyquinoline: synthesis, characterization, cytotoxicity, cell cycle and apoptosis.

    Qi-Pin Qin;Zhen-Feng Chen;Jiao-Lan Qin;Xiao-Ju He

  • X-Ray crystal structures of Mg2+ and Ca2+ dimers of the antibacterial drug norfloxacin

    Zhen-Feng Chen;Ren-Gen Xiong;Jing-Lin Zuo;Zijian Guo

  • Synthesis, Cytotoxic Activity, and DNA Binding Properties of Copper (II) Complexes with Hesperetin, Naringenin, and Apigenin

    Mingxiong Tan;Jinchan Zhu;Yingming Pan;Zhenfeng Chen

  • TCM active ingredient oxoglaucine metal complexes: crystal structure, cytotoxicity, and interaction with DNA.

    Zhen-Feng Chen;Yan-Fang Shi;Yan-Cheng Liu;Xue Hong

  • Amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays

    Yong Huang;Yong Huang;Shulin Zhao;Zhen-Feng Chen;Ming Shi

  • Study of the interaction of artemisinin with bovine serum albumin.

    Hedong Bian;Mei Li;Qing Yu;Zhenfeng Chen

  • Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) liriodenine with metal ions, and DNA binding studies.

    Zhen-Feng Chen;Yan-Cheng Liu;Yan-Cheng Liu;Li-Min Liu;Heng-Shan Wang

  • Hybrids of oxoisoaporphine-tacrine congeners: novel acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation inhibitors.

    Huang Tang;Li-Zhen Zhao;Hao-Tao Zhao;Shi-Liang Huang

  • Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dibromo-8-quinolinolato-lanthanides.

    Yan-Cheng Liu;Zhen-Feng Chen;Xiao-Yan Song;Yan Peng

  • Synthesis, characterization and preliminary cytotoxicity evaluation of five lanthanide(III)-plumbagin complexes.

    Zhen-Feng Chen;Ming-Xiong Tan;Ming-Xiong Tan;Yan-Cheng Liu;Yan Peng

  • Coordination polymers constructed by linking metal ions with azodibenzoate anions

    Zhen-Feng Chen;Zhi-Li Zhang;Yu-Hui Tan;Yun-Zhi Tang

Frequent Co-Authors

Hong Liang
Hong Liang Guangxi Normal University
Shulin Zhao
Shulin Zhao Guangxi Normal University
Xiao-Zeng You
Xiao-Zeng You Nanjing University
Hoong-Kun Fun
Hoong-Kun Fun Universiti Sains Malaysia
Chris Orvig
Chris Orvig University of British Columbia
You-Nian Liu
You-Nian Liu Central South University
Yong Zhang
Yong Zhang Soochow University
Ben Shen
Ben Shen Scripps Research Institute
Brendan F. Abrahams
Brendan F. Abrahams University of Melbourne
Zhongyuan Zhou
Zhongyuan Zhou Hong Kong Polytechnic University

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