D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 43 Citations 5,508 198 World Ranking 11629 National Ranking 1549

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • DNA
  • Enzyme

His scientific interests lie mostly in Stereochemistry, DNA, Crystal structure, Cytotoxicity and Crystallography. His studies deal with areas such as Topoisomerase, In vitro, Ligand and Metal ions in aqueous solution, Metal as well as Stereochemistry. His research integrates issues of Molecular biology, Aptamer, Biophysics and Structure–activity relationship in his study of DNA.

The Crystal structure study combines topics in areas such as Ion and Cadmium. His Cytotoxicity study incorporates themes from Intercalation, Agarose gel electrophoresis, Plumbagin, Membrane potential and Pifithrin. His work on Single crystal and Coordination polymer is typically connected to Quartz as part of general Crystallography study, connecting several disciplines of science.

His most cited work include:

  • 2D molecular square grid with strong blue fluorescent emission: a complex of norfloxacin with zinc(II). (157 citations)
  • Label-free colorimetric aptasensor based on nicking enzyme assisted signal amplification and DNAzyme amplification for highly sensitive detection of protein. (122 citations)
  • Stabilization of G-quadruplex DNA, inhibition of telomerase activity, and tumor cell apoptosis by organoplatinum(II) complexes with oxoisoaporphine. (100 citations)

What are the main themes of his work throughout his whole career to date?

Zhen-Feng Chen mostly deals with Stereochemistry, Crystal structure, Apoptosis, Cytotoxicity and Crystallography. Zhen-Feng Chen combines subjects such as Medicinal chemistry, Intercalation, Ligand and Agarose gel electrophoresis, DNA with his study of Stereochemistry. The Crystal structure study which covers Single crystal that intersects with Octahedron and Metal.

His Apoptosis study combines topics in areas such as Cell culture, In vitro and Molecular biology. In Cytotoxicity, he works on issues like Reactive oxygen species, which are connected to Cytochrome c. His Crystallography research incorporates themes from Lanthanide and Hydrogen bond.

He most often published in these fields:

  • Stereochemistry (31.03%)
  • Crystal structure (26.72%)
  • Apoptosis (22.84%)

What were the highlights of his more recent work (between 2017-2021)?

  • Apoptosis (22.84%)
  • Cytotoxicity (22.84%)
  • In vitro (9.48%)

In recent papers he was focusing on the following fields of study:

Zhen-Feng Chen focuses on Apoptosis, Cytotoxicity, In vitro, Stereochemistry and Cancer cell. The study incorporates disciplines such as Reactive oxygen species, Cancer research and Mitochondrion in addition to Apoptosis. His Cytotoxicity study is related to the wider topic of Biochemistry.

His In vitro research is multidisciplinary, relying on both Ligand, In vivo and Ligand. Many of his research projects under Stereochemistry are closely connected to Chebulic acid with Chebulic acid, tying the diverse disciplines of science together. His research investigates the link between Molecular biology and topics such as Tumor cells that cross with problems in Cell culture and DNA.

Between 2017 and 2021, his most popular works were:

  • Electrochemical sulfonylation of thiols with sulfonyl hydrazides: a metal- and oxidant-free protocol for the synthesis of thiosulfonates (44 citations)
  • Organometallic Gold(III) Complexes Similar to Tetrahydroisoquinoline Induce ER-Stress-Mediated Apoptosis and Pro-Death Autophagy in A549 Cancer Cells (32 citations)
  • Mitochondria-targeted platinum(II) complexes induce apoptosis-dependent autophagic cell death mediated by ER-stress in A549 cancer cells (25 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Enzyme
  • DNA

Zhen-Feng Chen mainly focuses on Apoptosis, Cytotoxicity, Cancer cell, Cancer research and Autophagy. He has researched Apoptosis in several fields, including Combinatorial chemistry, Cell culture and DNA. His Cell culture research integrates issues from Tumor cells, Platinum, Molecular biology, Telomerase and G-quadruplex.

He has included themes like Oxidative stress, Cell, Molecule, Copper and Derivative in his DNA study. Zhen-Feng Chen performs multidisciplinary studies into Cytotoxicity and Inhibitory postsynaptic potential in his work. His work deals with themes such as Stereochemistry and Cyclin A, which intersect with Intracellular.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

2D molecular square grid with strong blue fluorescent emission: a complex of norfloxacin with zinc(II).

Zhen-Feng Chen;Ren-Gen Xiong;Jing Zhang;Xue-Tai Chen.
Inorganic Chemistry (2001)

227 Citations

Label-free colorimetric aptasensor based on nicking enzyme assisted signal amplification and DNAzyme amplification for highly sensitive detection of protein.

Yong Huang;Jia Chen;Shulin Zhao;Ming Shi.
Analytical Chemistry (2013)

182 Citations

An unprecedented six-fold anion-type chiral diamondoid-like eight-coordinate Cd(II) coordination polymer with a second-order nonlinear optical effect

Zhen-Feng Chen;Ren-Gen Xiong;Brendan F. Abrahams;Xiao-Zeng You.
Journal of The Chemical Society-dalton Transactions (2001)

126 Citations

In situ ligand synthesis and the first crystallographically characterized lanthanide 3-D pillared networks containing benzene-1,4-disulfonate as a building block

Ren-Gen Xiong;Jing Zhang;Zhen-Feng Chen;Xiao-Zeng You.
Journal of The Chemical Society-dalton Transactions (2001)

121 Citations

Stabilization of G-quadruplex DNA, inhibition of telomerase activity, and tumor cell apoptosis by organoplatinum(II) complexes with oxoisoaporphine.

Zhen-Feng Chen;Qi-Pin Qin;Jiao-Lan Qin;Yan-Cheng Liu.
Journal of Medicinal Chemistry (2015)

115 Citations

Samarium(III)-Catalyzed C(sp3)–H Bond Activation: Synthesis of Indolizines via C–C and C–N Coupling between 2-Alkylazaarenes and Propargylic Alcohols

Xu Wang;Shen-yan Li;Ying-ming Pan;Heng-shan Wang.
Organic Letters (2014)

110 Citations

Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis

Zhen-Feng Chen;Qi-Pin Qin;Jiao-Lan Qin;Jie Zhou.
Journal of Medicinal Chemistry (2015)

107 Citations

X-Ray crystal structures of Mg2+ and Ca2+ dimers of the antibacterial drug norfloxacin

Zhen-Feng Chen;Ren-Gen Xiong;Jing-Lin Zuo;Zijian Guo.
Journal of The Chemical Society-dalton Transactions (2000)

106 Citations

Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) liriodenine with metal ions, and DNA binding studies.

Zhen-Feng Chen;Yan-Cheng Liu;Yan-Cheng Liu;Li-Min Liu;Heng-Shan Wang.
Dalton Transactions (2009)

95 Citations

Amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays

Yong Huang;Yong Huang;Shulin Zhao;Zhen-Feng Chen;Ming Shi.
Chemical Communications (2012)

94 Citations

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