Lei Shi

Overview

Best Publications

• Structure of the human dopamine d3 receptor in complex with a d2/d3 selective antagonist.

  Ellen Y. T. Chien;Wei Liu;Qiang Zhao;Vsevolod Katritch

  1340
  Citations

• Activation of the β2-Adrenergic Receptor Involves Disruption of an Ionic Lock between the Cytoplasmic Ends of Transmembrane Segments 3 and 6

  Juan A. Ballesteros;Anne D. Jensen;George Liapakis;George Liapakis;Søren G.F. Rasmussen

  810
  Citations

• Acetyl-CoA and the regulation of metabolism: mechanisms and consequences

  Lei Shi;Benjamin P Tu

  737
  Citations

• Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors.

  Juan A. Ballesteros;Lei Shi;Jonathan A. Javitch

  548
  Citations

• β2 Adrenergic Receptor Activation MODULATION OF THE PROLINE KINK IN TRANSMEMBRANE 6 BY A ROTAMER TOGGLE SWITCH

  Lei Shi;George Liapakis;Rui Xu;Frank Guarnieri

  503
  Citations

• Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism.

  Christine Saunders;Jasmine V. Ferrer;Lei Shi;Jiayun Chen

  488
  Citations

• The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site.

  Lei Shi;Matthias Quick;Yongfang Zhao;Harel Weinstein

  442
  Citations

• The binding sites for cocaine and dopamine in the dopamine transporter overlap

  Thijs Beuming;Julie Kniazeff;Marianne L Bergmann;Lei Shi

  421
  Citations

• The binding site of aminergic G protein-coupled receptors: the transmembrane segments and second extracellular loop.

  Lei Shi;Jonathan A Javitch

  407
  Citations

• Mannose-binding Lectin-deficient Mice Are Susceptible to Infection with Staphylococcus aureus

  Lei Shi;Kazue Takahashi;Joseph Dundee;Sarit Shahroor-Karni

  404
  Citations

• Dopamine D2 receptors form higher order oligomers at physiological expression levels

  Wen Guo;Eneko Urizar;Michaela Kralikova;Juan Carlos Mobarec

  391
  Citations

• A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function.

  Thijs Beuming;Lei Shi;Jonathan A. Javitch;Harel Weinstein

  388
  Citations

• SNOSID, a proteomic method for identification of cysteine S-nitrosylation sites in complex protein mixtures.

  Gang Hao;Behrad Derakhshan;Lei Shi;Fabien Campagne

  386
  Citations

• The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer.

  Wen Guo;Lei Shi;Jonathan A. Javitch

  345
  Citations

• Crosstalk in G protein-coupled receptors: Changes at the transmembrane homodimer interface determine activation

  Wen Guo;Lei Shi;Marta Filizola;Harel Weinstein

  322
  Citations

• Mannose-Binding Lectin Is a Regulator of Inflammation That Accompanies Myocardial Ischemia and Reperfusion Injury

  Mary C. Walsh;Todd Bourcier;Kazue Takahashi;Lei Shi

  316
  Citations

• Mannose-Binding Lectin-Deficient Mice Display Defective Apoptotic Cell Clearance but No Autoimmune Phenotype

  Lynda M. Stuart;Lynda M. Stuart;Kazue Takahashi;Lei Shi;John Savill

  315
  Citations

• Substrate-modulated gating dynamics in a Na + -coupled neurotransmitter transporter homologue

  Yongfang Zhao;Daniel S. Terry;Lei Shi;Matthias Quick

  313
  Citations

• TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion–Positive Intrahepatic Cholangiocarcinoma

  Lipika Goyal;Lei Shi;Leah Y Liu;Ferran Fece de la Cruz

  307
  Citations

• P085. SNOSID, a proteomic method for identification of cysteine S-nitrosylation sites in complex protein mixtures

  Steven S. Gross;Gang Hao;Behrad Derakhshan;M. Carrie Garceau

  2
  Citations