World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
91
Citations
28490
World Ranking
1978
National Ranking
724

Biology and Biochemistry

D-Index
92
Citations
28968
World Ranking
2220
National Ranking
1198

Overview

Harel Weinstein is affiliated with Cornell University in the United States and has a strong research profile primarily in biochemistry, genetics, and molecular biology. Their work spans several subfields including molecular biology, infectious diseases, spectroscopy, cell biology, and cellular and molecular neuroscience.

Weinstein has contributed extensively to topics such as lipid membrane structure and behavior, protein structure and dynamics, research related to SARS-CoV-2 and COVID-19, RNA and protein synthesis mechanisms, ion channel regulation and function, receptor mechanisms and signaling, and mass spectrometry techniques and applications.

Frequent coauthors collaborating with Weinstein include:

  • George Khelashvili
  • Ekaterina D. Kots
  • Hengyi Xie
  • Ambrose Plante
  • Xiaolu Cheng

They have published frequently in several venues, including:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The FASEB Journal
  • Nature Methods
  • Molecules

Among Weinstein's recent research papers are:

  • Localization atomic force microscopy, 2021, Nature
  • GPCRmd uncovers the dynamics of the 3D-GPCRome, 2020, Nature Methods
  • Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication, 2022, Science Signaling
  • Ca2+-dependent mechanism of membrane insertion and destabilization by the SARS-CoV-2 fusion peptide, 2021, Biophysical Journal
  • The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • [19] Integrated methods for the construction of three-dimensional models and computational probing of structure-function relations in G protein-coupled receptors

    Juan A. Ballesteros;Harel Weinstein

  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology

    Jonathan D. Urban;William P. Clarke;Mark Von Zastrow;David E. Nichols

  • Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac.

    Marianna Max;Y. Gopi Shanker;Liquan Huang;Minqing Rong

  • Molecular Mechanisms of Ligand Interaction with the Gonadotropin-Releasing Hormone Receptor

    Stuart C. Sealfon;Harel Weinstein;Robert P. Millar

  • Agonists induce conformational changes in transmembrane domains III and VI of the β2 adrenoceptor

    Ulrik Gether;Sansan Lin;Pejman Ghanouni;Juan A. Ballesteros

  • The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site.

    Lei Shi;Matthias Quick;Yongfang Zhao;Harel Weinstein

  • The binding sites for cocaine and dopamine in the dopamine transporter overlap

    Thijs Beuming;Julie Kniazeff;Marianne L Bergmann;Lei Shi

  • Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation.

    Yang Han;Irina S Moreira;Eneko Urizar;Harel Weinstein

  • A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function.

    Thijs Beuming;Lei Shi;Jonathan A. Javitch;Harel Weinstein

  • Single-molecule analysis of ligand efficacy in β2AR–G-protein activation

    G. Glenn Gregorio;Matthieu Masureel;Daniel Hilger;Daniel S. Terry

  • Hinges, swivels and switches: the role of prolines in signalling via transmembrane α-helices

    Mark S.P. Sansom;Harel Weinstein

  • Structural Instability of a Constitutively Active G Protein-coupled Receptor AGONIST-INDEPENDENT ACTIVATION DUE TO CONFORMATIONAL FLEXIBILITY

    U Gether;J A Ballesteros;R Seifert;E Sanders-Bush

  • A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor.

    Wei Zhou;C. Flanagan;J. A. Ballesteros;K. Konvicka

  • Functional Microdomains in G-protein-coupled Receptors THE CONSERVED ARGININE-CAGE MOTIF IN THE GONADOTROPIN-RELEASING HORMONE RECEPTOR

    Juan Ballesteros;Smiljka Kitanovic;Frank Guarnieri;Peter Davies

  • Crosstalk in G protein-coupled receptors: Changes at the transmembrane homodimer interface determine activation

    Wen Guo;Lei Shi;Marta Filizola;Harel Weinstein

  • Substrate-modulated gating dynamics in a Na + -coupled neurotransmitter transporter homologue

    Yongfang Zhao;Daniel S. Terry;Lei Shi;Matthias Quick

  • Single-molecule dynamics of gating in a neurotransmitter transporter homologue

    Yongfang Zhao;Daniel Terry;Lei Shi;Harel Weinstein

  • A detailed interpretation of OH radical footprints in a TBP-DNA complex reveals the role of dynamics in the mechanism of sequence-specific binding.

    Nina Pastor;Harel Weinstein;Elizabeth Jamison;Michael Brenowitz

  • Related Contribution of Specific Helix 2 and 7 Residues to Conformational Activation of the Serotonin 5-HT2A Receptor

    Stuart C. Sealfon;Ling Chi;Barbara J. Ebersole;Vladimir Rodic

  • PDZBase: a protein--protein interaction database for PDZ-domains

    Thijs Beuming;Lucy Skrabanek;Masha Y. Niv;Piali Mukherjee

Frequent Co-Authors

Lei Shi
Lei Shi National Institute on Drug Abuse
Jonathan A. Javitch
Jonathan A. Javitch Columbia University
Ulrik Gether
Ulrik Gether University of Copenhagen
Stuart C. Sealfon
Stuart C. Sealfon Icahn School of Medicine at Mount Sinai
Leonardo Pardo
Leonardo Pardo Autonomous University of Barcelona
Scott C. Blanchard
Scott C. Blanchard St. Jude Children's Research Hospital
Olaf S. Andersen
Olaf S. Andersen Cornell University
Aurelio Galli
Aurelio Galli University of Alabama at Birmingham
Mordechai Sokolovsky
Mordechai Sokolovsky Tel Aviv University
Anant K. Menon
Anant K. Menon Cornell University

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