2026 Patrick M. Sexton: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	101	1445	1300	36	35	438	36379

Research.com Recognitions

2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Patrick M. Sexton is affiliated with Monash University in Australia and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology, Cellular and Molecular Neuroscience, and Endocrinology, Diabetes and Metabolism. Their research addresses multiple specialized areas such as Receptor Mechanisms and Signaling, Neuropeptides and Animal Physiology, and Diabetes Treatment and Management.

Sexton's work includes publications in prominent scientific journals, demonstrating a capacity to engage with complex biochemical and molecular topics across diverse research venues. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Biochemical Pharmacology, Nature Chemical Biology, and ACS Pharmacology & Translational Science.

Recent notable papers include:

Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists, 2020, Molecular Cell
Activation of the GLP-1 receptor by a non-peptidic agonist, 2020, Nature
Structural basis of G _s and G _i recognition by the human glucagon receptor, 2020, Science
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia, 2021, Nature
Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation, 2020, Molecular Cell

The scientist has collaborated frequently with several co-authors, including Denise Wootten, Craig W. Lindsley, Cynthia J. Burrows, Shu Wang, and Hyun Jae Kim. These collaborations often span multiple publications, reflecting ongoing research partnerships.

Main research topics covered in Sexton's work include:

Receptor Mechanisms and Signaling
Neuropeptides and Animal Physiology
Diabetes Treatment and Management
Neuroscience and Neuropharmacology Research
Monoclonal and Polyclonal Antibodies Research
Mass Spectrometry Techniques and Applications
Nicotinic Acetylcholine Receptors Study

Subfields of study pertinent to Sexton's research encompass:

Molecular Biology
Cellular and Molecular Neuroscience
Endocrinology, Diabetes and Metabolism
Radiology, Nuclear Medicine and Imaging
Spectroscopy

Best Publications

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

Jonathan D. Urban;William P. Clarke;Mark Von Zastrow;David E. Nichols

1317
Citations
Activation and allosteric modulation of a muscarinic acetylcholine receptor

Andrew C. Kruse;Aaron M. Ring;Aashish Manglik;Jianxin Hu

1015
Citations
International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors.

David R. Poyner;Patrick M. Sexton;Ian Marshall;David M. Smith

968
Citations
Allosteric modulation of G protein-coupled receptors.

Lauren T May;Katie Leach;Patrick M Sexton;Arthur Christopoulos

805
Citations
Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization.

G.C. Nicholson;J.M. Moseley;P.M. Sexton;F.A.O. Mendelsohn

582
Citations
Mechanisms of signalling and biased agonism in G protein-coupled receptors

Denise L Wootten;Arthur Christopoulos;Maria Marti-Solano;M. Madan Babu

580
Citations
Multiple Amylin Receptors Arise from Receptor Activity- Modifying Protein Interaction with the Calcitonin Receptor Gene Product

George Christopoulos;Katie J. Perry;Maria Morfis;Nanda Tilakaratne

557
Citations
G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor

Evi Kostenis;Graeme Milligan;Arthur Christopoulos;Carlos F. Sanchez-Ferrer

536
Citations
Emerging paradigms in GPCR allostery: implications for drug discovery

Denise Laura Wootten;Arthur Christopoulos;Patrick Sexton

511
Citations
Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

Yi Lynn Liang;Maryam Khoshouei;Mazdak Radjainia;Yan Zhang

485
Citations
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs

Ron O. Dror;Hillary F. Green;Celine Valant;David W. Borhani

457
Citations
Glucagon-like peptide-1 and its class B G protein-coupled receptors: A long march to therapeutic successes

Chris de Graaf;Dan Donnelly;Denise Wootten;Jesper Lau

432
Citations
Muscarinic acetylcholine receptors: novel opportunities for drug development

Andrew C. Kruse;Brian K. Kobilka;Dinesh Gautam;Patrick M. Sexton

427
Citations
Drug Transporters in Drug Efficacy and Toxicity

M K DeGorter;C Q Xia;J J Yang;R B Kim

394
Citations
Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology.

Katherine Leach;Patrick Sexton;Arthur Christopoulos

387
Citations
The role of kinetic context in apparent biased agonism at GPCRs

Carmen Klein Herenbrink;David A. Sykes;Prashant Donthamsetti;Meritxell Canals

355
Citations
Novel Receptor Partners and Function of Receptor Activity-modifying Proteins

Arthur Christopoulos;George Christopoulos;Maria Morfis;Madhara Udawela

343
Citations
Crystal structures of the M1 and M4 muscarinic acetylcholine receptors.

David M. Thal;Bingfa Sun;Dan Feng;Vindhya Nawaratne

340
Citations
Structure of the adenosine-bound human adenosine A 1 receptor-G i complex.

Christopher J. Draper-Joyce;Maryam Khoshouei;Maryam Khoshouei;David M. Thal;Yi Lynn Liang

331
Citations
In vitro autoradiographic localization of amylin binding sites in rat brain.

P.M. Sexton;G. Paxinos;M.A. Kenney;P.J. Wookey

315
Citations