World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
20974
World Ranking
7677
National Ranking
3500

Overview

Terry P. Kenakin is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans multiple interconnected disciplines with a focus on the biochemical and molecular mechanisms underlying receptor function and signaling.

The main fields of study for this scientist include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

The subfields in which they have contributed include:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Pharmacology
  • Radiology, Nuclear Medicine and Imaging
  • Computational Theory and Mathematics

The primary topics of research are centered around:

  • Receptor Mechanisms and Signaling
  • Neuropeptides and Animal Physiology
  • Monoclonal and Polyclonal Antibodies Research
  • Computational Drug Discovery Methods
  • Pharmacogenetics and Drug Metabolism
  • Neuroscience and Neuropharmacology Research
  • Pharmacological Receptor Mechanisms and Effects

Recent publications authored by or involving Terry P. Kenakin include:

  • Virtual discovery of melatonin receptor ligands to modulate circadian rhythms (2020), published in Nature
  • Community guidelines for GPCR ligand bias: IUPHAR review 32 (2022), published in British Journal of Pharmacology
  • Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator (2023), published in Biochemistry
  • The function and allosteric control of the human sweet taste receptor (2020), published in Advances in Pharmacology
  • Interdependent allosteric free fatty acid receptor 2 modulators synergistically induce functional selective activation and desensitization in neutrophils (2020), published in Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Frequent co-authors associated with this researcher include:

  • Bryan L. Roth
  • Xi-Ping Huang
  • Hye Jin Kang
  • B. Krumm
  • Susruta Majumdar

The scientist has published extensively, with many publications accessible through UNC Libraries and contributions appearing repeatedly in journals such as the British Journal of Pharmacology and Biochemistry. Their work often involves molecular and pharmacological characterization of receptor behavior and ligand interactions, highlighting an emphasis on computational approaches and experimental pharmacology.

Best Publications

  • G Protein-Coupled Receptor Allosterism and Complexing

    Arthur Christopoulos;Terry Kenakin

  • Agonist-receptor efficacy II: agonist trafficking of receptor signals

    Terry Kenakin

  • Seven Transmembrane Receptors as Shapeshifting Proteins: The Impact of Allosteric Modulation and Functional Selectivity on New Drug Discovery

    Terry P. Kenakin;Laurence J. Miller

  • Signalling bias in new drug discovery: detection, quantification and therapeutic impact

    Terrence Peter Kenakin;Arthur Christopoulos

  • International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology

    Richard R. Neubig;Michael Spedding;Terry Kenakin;Arthur Christopoulos

  • Functional Selectivity and Biased Receptor Signaling

    Terry Kenakin

  • Inverse, protean, and ligand-selective agonism: matters of receptor conformation

    Terry Kenakin

  • Principles: receptor theory in pharmacology.

    Terry Kenakin

  • Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor

    R A Bond;P Leff;T D Johnson;C A Milano

  • A simple method for quantifying functional selectivity and agonist bias.

    Terry Kenakin;Christian Watson;Vanessa Muniz-Medina;Arthur Christopoulos

  • Ligand-selective receptor conformations revisited: the promise and the problem.

    Terry Kenakin

  • Drug Efficacy at G Protein–Coupled Receptors

    Terry Kenakin

  • New Concepts in Drug Discovery: Collateral Efficacy and Permissive Antagonism

    Terry Kenakin

  • The classification of seven transmembrane receptors in recombinant expression systems.

    Terry Kenakin

  • Functional selectivity through protean and biased agonism: who steers the ship?

    Terry P Kenakin

  • Efficacy at g-protein-coupled receptors

    Terry Kenakin

  • Biased signalling and allosteric machines: new vistas and challenges for drug discovery

    Terry P Kenakin

  • Efficacy as a vector: the relative prevalence and paucity of inverse agonism.

    Terry Kenakin

  • Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors.

    Terry Kenakin

  • The Cubic Ternary Complex Receptor-Occupancy Model III. Resurrecting Efficacy

    Jack M. Weiss;Paul H. Morgan;Michael W. Lutz;Terry P. Kenakin

Frequent Co-Authors

Arthur Christopoulos
Arthur Christopoulos Monash University
Jenny L. Wiley
Jenny L. Wiley RTI International
Xi Ping Huang
Xi Ping Huang University of North Carolina at Chapel Hill
Brian K. Shoichet
Brian K. Shoichet University of California, San Francisco
Luc Maroteaux
Luc Maroteaux Université Paris Cité
Evi Kostenis
Evi Kostenis University of Bonn
Jenny L. Wiley
Jenny L. Wiley Research Triangle Park Foundation
Jian Jin
Jian Jin Icahn School of Medicine at Mount Sinai
Claes Dahlgren
Claes Dahlgren University of Gothenburg
Jianjun Cheng
Jianjun Cheng University of Illinois at Urbana-Champaign

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those studying Biology and Biochemistry in the USA, a variety of online degree options offer new ways to advance your education and career. Many professionals are choosing flexible programs designed for busy schedules, opening up opportunities in rapidly growing areas of healthcare and science.

For example, if you’re interested in advanced nursing roles, you can explore a doctor of nursing practice degree online, sometimes without clinical hours required. If healthcare leadership or administration is your goal, consider earning an online phd in healthcare management. Both programs can be a perfect next step for biochemistry and biology graduates aiming for leadership.

Students looking to combine chemistry with patient care might be interested in pharmacy. Accredited pharmd online programs allow you to advance your expertise while balancing work and study commitments.

If your focus is human performance or physical health, an exercise science degree online can help you build a career in fitness, rehab, or wellness fields. These pathways demonstrate how Biology and Biochemistry lay a strong foundation for diverse and rewarding career options.

Best Scientists Citing Terry P. Kenakin

Trending Scientists

Recently Published Articles