Xi Ping Huang

Overview

Best Publications

• A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

  David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  5396
  Citations

• NMDAR inhibition-independent antidepressant actions of ketamine metabolites

  Panos Zanos;Ruin Moaddel;Patrick J. Morris;Polymnia Georgiou

  1669
  Citations

• Structure of the human κ-opioid receptor in complex with JDTic

  Huixian Wu;Daniel Wacker;Mauro Mileni;Vsevolod Katritch

  1078
  Citations

• Structure-based discovery of opioid analgesics with reduced side effects

  Aashish Manglik;Henry Lin;Dipendra K. Aryal;John D. McCorvy

  1014
  Citations

• Automated design of ligands to polypharmacological profiles

  Jérémy Besnard;Gian Filippo Ruda;Vincent Setola;Keren Abecassis

  907
  Citations

• Structural Features for Functional Selectivity at Serotonin Receptors

  Daniel Wacker;Chong Wang;Vsevolod Katritch;Gye Won Han

  799
  Citations

• PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

  Wesley K. Kroeze;Maria F. Sassano;Xi Ping Huang;Katherine Lansu

  657
  Citations

• A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

  Masoud Vedadi;Dalia Barsyte-Lovejoy;Feng Liu;Sylvie Rival-Gervier

  608
  Citations

• Structural Basis for Molecular Recognition at Serotonin Receptors

  Chong Wang;Yi Jiang;Yi Jiang;Jinming Ma;Jinming Ma;Huixian Wu

  605
  Citations

• Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.

  Aaron A. Thompson;Wei-Wei Liu;Eugene Chun;Vsevolod Katritch

  585
  Citations

• Molecular control of δ-opioid receptor signalling

  Gustavo Fenalti;Patrick M. Giguere;Vsevolod Katritch;Xi Ping Huang

  543
  Citations

• Structure of the human smoothened receptor bound to an antitumour agent

  Chong Wang;Huixian Wu;Vsevolod Katritch;Gye Won Han

  537
  Citations

• An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1.

  Kyle D. Konze;Anqi Ma;Fengling Li;Dalia Barsyte-Lovejoy

  477
  Citations

• A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior

  Eyal Vardy;J. Elliott Robinson;Chia Li;Chia Li;Reid H.J. Olsen

  440
  Citations

• Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys.

  Yuji Nagai;Naohisa Miyakawa;Hiroyuki Takuwa;Yukiko Hori

  413
  Citations

• Discovery of β-Arrestin–Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy

  John A. Allen;Julianne M. Yost;Vincent Setola;Xin Chen

  398
  Citations

• Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

  Tao Che;Susruta Majumdar;Saheem A. Zaidi;Pauline Ondachi

  374
  Citations

• Comprehensive characterization of the Published Kinase Inhibitor Set

  Jonathan M. Elkins;Vita Fedele;Marta Szklarz;Kamal R. Abdul Azeez

  357
  Citations

• Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo

  Atheir I. Abbas;Peter B. Hedlund;Xi Ping Huang;Thuy B. Tran

  351
  Citations

• Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs.

  Chong Wang;Huixian Wu;Tama Evron;Eyal Vardy

  274
  Citations