World's Best Scientists 2026 revealed!
VIEW LIST
Stephen V. Frye

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
17190
World Ranking
9544
National Ranking
4212

Stephen V. Frye publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Stephen V. Frye sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 237 publications — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Stephen V. Frye D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Stephen V. Frye sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 64 D-Index — 52nd percentile

52% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Stephen V. Frye is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans multiple disciplines, primarily in Biochemistry, Genetics, and Molecular Biology, with a significant portion of work also connected to Medicine.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad areas, Frye's research focuses on specific subfields such as Molecular Biology, Immunology, Organic Chemistry, Computational Theory and Mathematics, and Oncology.

  • Molecular Biology
  • Immunology
  • Organic Chemistry
  • Computational Theory and Mathematics
  • Oncology

The scientist's work addresses various research topics, including:

  • Phagocytosis and Immune Regulation
  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • Computational Drug Discovery Methods
  • Genomics and Chromatin Dynamics
  • Cell death mechanisms and regulation
  • Protein Degradation and Inhibitors

Frye has published in multiple frequent venues where their research output is notably present. These venues include:

  • UNC Libraries
  • OPAL (Open@LaTrobe) (La Trobe University)
  • Cancer Research
  • Journal of Medicinal Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)

Collaborative efforts form a significant part of Frye's work, with frequent co-authors being:

  • Xiaodong Wang
  • Dmitri Kireev
  • H. Shelton Earp
  • Lindsey I. James
  • Deborah DeRyckere

The scientist's recent notable papers, indicating ongoing research trends and areas of emphasis, include:

  • Target 2035 - update on the quest for a probe for every protein, 2021, RSC Medicinal Chemistry
  • PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components, 2023, ACS Chemical Biology
  • MERTK activation drives osimertinib resistance in EGFR-mutant non-small cell lung cancer, 2022, Journal of Clinical Investigation
  • MerTK inhibition decreases immune suppressive glioblastoma-associated macrophages and neoangiogenesis in glioblastoma microenvironment, 2020, Neuro-Oncology Advances
  • Discovery and Optimization of 2H-1λ2-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer, 2021, Journal of Medicinal Chemistry

Best Publications

  • Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

    Wei Xu;Hui Yang;Ying Liu;Ying Yang

  • The promise and peril of chemical probes.

    Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

  • Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer

    James S. Duncan;Martin C. Whittle;Kazuhiro Nakamura;Amy N. Abell

  • A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

    Masoud Vedadi;Dalia Barsyte-Lovejoy;Feng Liu;Sylvie Rival-Gervier

  • An orally bioavailable chemical probe of the Lysine Methyltransferases EZH2 and EZH1.

    Kyle D. Konze;Anqi Ma;Fengling Li;Dalia Barsyte-Lovejoy

  • Too many roads not taken

    Aled M Edwards;Ruth Isserlin;Gary D Bader;Stephen V Frye

  • The art of the chemical probe

    Stephen V Frye

  • Discovery of β-Arrestin–Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy

    John A. Allen;Julianne M. Yost;Vincent Setola;Xin Chen

  • The human genome and drug discovery after a decade. Roads (still) not taken

    Ruth Isserlin;Gary D. Bader;Aled Edwards;Stephen Frye

  • Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis.

    H.N. Bramson;J. Corona;S.T. Davis;S.H. Dickerson

  • The discovery of potent cRaf1 kinase inhibitors

    Karen Lackey;Michael Cory;Ronda Davis;Stephen V. Frye

  • Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.

    Feng Liu;Dalia Barsyte-Lovejoy;Fengling Li;Yan Xiong

  • Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity

    Bret D. Wallace;Adam B. Roberts;Rebecca M. Pollet;James D. Ingle

  • Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.

    Feng Liu;Xin Chen;Abdellah Allali-Hassani;Amy M. Quinn

  • Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors.

    Stephen T. Davis;Bill G. Benson;H. Neal Bramson;Dennis E. Chapman

  • Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia

    Bowen Xu;Doan M. On;Anqi Ma;Trevor Parton

  • Protein lysine methyltransferase g9a inhibitors: Design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines.

    Feng Liu;Xin Chen;Abdellah Allali-Hassani;Amy M. Quinn

  • Chelates as intermediates in nucleophilic additions to alkoxy ketones according to Cram's rule (cyclic model)

    Xiangning Chen;Edwin R. Hortelano;Ernest L. Eliel;Stephen V. Frye

  • Unique Preclinical Characteristics of GG745, A Potent Dual Inhibitor of 5AR

    H N Bramson;D Hermann;K W Batchelor;F W Lee

  • Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain

    Lindsey I. James;Dalia Barsyte-Lovejoy;Nan Zhong;Liubov Krichevsky

Frequent Co-Authors

H. Shelton Earp
H. Shelton Earp University of North Carolina at Chapel Hill
Jian Jin
Jian Jin Icahn School of Medicine at Mount Sinai
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Peter Brown
Peter Brown University of Oxford
Masoud Vedadi
Masoud Vedadi Structural Genomics Consortium
Bryan L. Roth
Bryan L. Roth University of North Carolina at Chapel Hill
Mark T. Bedford
Mark T. Bedford The University of Texas MD Anderson Cancer Center
Aled M. Edwards
Aled M. Edwards Structural Genomics Consortium
Stefan Knapp
Stefan Knapp Goethe University Frankfurt
Timothy M. Willson
Timothy M. Willson University of North Carolina at Chapel Hill

External Links

Personal website of Stephen V. Frye

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Stephen V. Frye

Cheryl H. Arrowsmith

Cheryl H. Arrowsmith

Structural Genomics Consortium

Publications: 92

Jian Jin

Jian Jin

Icahn School of Medicine at Mount Sinai

Publications: 79

Masoud Vedadi

Masoud Vedadi

Structural Genomics Consortium

Publications: 73

Stefan Knapp

Stefan Knapp

Goethe University Frankfurt

Publications: 67

Matthieu Schapira

Matthieu Schapira

University of Toronto

Publications: 61

Gary L. Johnson

Gary L. Johnson

University of North Carolina at Chapel Hill

Publications: 47

Bryan L. Roth

Bryan L. Roth

University of North Carolina at Chapel Hill

Publications: 44

Peter Brown

Peter Brown

University of Oxford

Publications: 43

Yue Xiong

Yue Xiong

University of North Carolina at Chapel Hill

Publications: 37

Susanne Müller

Susanne Müller

Structural Genomics Consortium

Publications: 36

Ruedi Aebersold

Ruedi Aebersold

ETH Zurich

Publications: 34

Paul Brennan

Paul Brennan

International Agency For Research On Cancer

Publications: 33

Kun-Liang Guan

Kun-Liang Guan

Westlake University

Publications: 31

Lee M. Graves

Lee M. Graves

University of North Carolina at Chapel Hill

Publications: 30

Ross L. Levine

Ross L. Levine

Memorial Sloan Kettering Cancer Center

Publications: 30

Dalia Barsyte-Lovejoy

Dalia Barsyte-Lovejoy

Structural Genomics Consortium

Publications: 29

Trending Scientists

Frank Vollertsen

Frank Vollertsen

Bremen Institute for Applied Beam Technology

Taane G. Clark

Taane G. Clark

London School of Hygiene & Tropical Medicine

Wayne J. Book

Wayne J. Book

Georgia Institute of Technology

Geoff V. Merrett

Geoff V. Merrett

University of Southampton

Mario Amore

Mario Amore

University of Genoa

Mitsuyuki Matsumoto

Mitsuyuki Matsumoto

Astellas Pharma (Japan)

Jean-Christophe Cassel

Jean-Christophe Cassel

University of Strasbourg

Matthew N.J. Seaman

Matthew N.J. Seaman

University of Cambridge

Fabienne Willems

Fabienne Willems

Université Libre de Bruxelles

Ning Qin

Ning Qin

University of Sheffield

Mark R. Antonio

Mark R. Antonio

Colorado School of Mines

Bing Hu

Bing Hu

Nanjing Agricultural University

Thomas R. Hoye

Thomas R. Hoye

University of Minnesota

Alan E. Gelfand

Alan E. Gelfand

Duke University

Ana Almodóvar

Ana Almodóvar

Complutense University of Madrid

Wayne D. Hoyer

Wayne D. Hoyer

The University of Texas at Austin

Related Biology and Biochemistry Rankings & Guides

2026 How to Become an OB-GYN Sonographer: Education, Salary, and Job Outlook

2026 How to Become an OB-GYN Sonographer: Education, Salary, and Job Outlook
2026 How Fast Can You Get a Health Sciences Degree Online?

2026 How Fast Can You Get a Health Sciences Degree Online?
2026 How to Become a Neurological Nurse Practitioner: Education, Salary, and Job Outlook

2026 How to Become a Neurological Nurse Practitioner: Education, Salary, and Job Outlook
2026 Is a Healthcare Administration Online Degree Worth It?

2026 Is a Healthcare Administration Online Degree Worth It?
2026 How to Become a Pediatric Occupational Therapist: Education, Salary, and Job Outlook

2026 How to Become a Pediatric Occupational Therapist: Education, Salary, and Job Outlook
2026 Fastest Online Healthcare Administration Degree Programs You Can Finish in Under 2 Years

2026 Fastest Online Healthcare Administration Degree Programs You Can Finish in Under 2 Years
2026 Easiest Online Psychiatric Mental Health Nurse Practitioner Degree Programs That Pay Well: High-Salary Degrees with Simple Admissions

2026 Easiest Online Psychiatric Mental Health Nurse Practitioner Degree Programs That Pay Well: High-Salary Degrees with Simple Admissions
2026 Most Affordable Online Master’s in Bioinformatics Programs

2026 Most Affordable Online Master’s in Bioinformatics Programs
2026 MRI Tech vs. Radiology Tech: Explaining the Difference

2026 MRI Tech vs. Radiology Tech: Explaining the Difference
2026 Fastest Online Adult Gerontology Primary Care Nurse Practitioner Degree Programs You Can Finish in Under 2 Years

2026 Fastest Online Adult Gerontology Primary Care Nurse Practitioner Degree Programs You Can Finish in Under 2 Years
2026 Is Health Information Management a Hard Major? What Students Should Know

2026 Is Health Information Management a Hard Major? What Students Should Know
2026 How Fast Can You Get a Medical Assisting Degree Online?

2026 How Fast Can You Get a Medical Assisting Degree Online?
2026 What Prerequisites Do You Need for a Nutrition Degree? Entry Requirements, Credits & Eligibility Rules

2026 What Prerequisites Do You Need for a Nutrition Degree? Entry Requirements, Credits & Eligibility Rules
2026 How to Become a Cath Lab Tech: Education, Salary, and Job Outlook

2026 How to Become a Cath Lab Tech: Education, Salary, and Job Outlook
2026 Online Medical Billing & Coding Degree Programs for Veterans: GI Bill Benefits, Costs & Top Considerations

2026 Online Medical Billing & Coding Degree Programs for Veterans: GI Bill Benefits, Costs & Top Considerations
2026 Online Pharmacy Degree Programs for Veterans: GI Bill Benefits, Costs & Top Considerations

2026 Online Pharmacy Degree Programs for Veterans: GI Bill Benefits, Costs & Top Considerations
2026 How Much Does a Nurse Leadership Degree Program Cost? Tuition, Fees & Total Expense Breakdown

2026 How Much Does a Nurse Leadership Degree Program Cost? Tuition, Fees & Total Expense Breakdown
2026 Is a Care Coordination Online Degree Worth It?

2026 Is a Care Coordination Online Degree Worth It?
2026 Fastest Online Biology and Biological Sciences Bachelor's Degree Programs You Can Finish in 3 Years or Less

2026 Fastest Online Biology and Biological Sciences Bachelor's Degree Programs You Can Finish in 3 Years or Less
2026 Medical Assistant vs. Medical Coder: Explaining the Difference

2026 Medical Assistant vs. Medical Coder: Explaining the Difference
2026 How to Become a Clinical Research Associate: Education, Salary, and Job Outlook

2026 How to Become a Clinical Research Associate: Education, Salary, and Job Outlook

Recently Published Articles

2026 Is a Marriage & Family Counseling Online Degree Worth It?

2026 Is a Marriage & Family Counseling Online Degree Worth It?
2026 Online Cybersecurity Degree Master's Programs That Accept Transfer Credits

2026 Online Cybersecurity Degree Master's Programs That Accept Transfer Credits
2026 Online Spanish Degree Programs for Veterans: GI Bill Benefits, Costs & Top Considerations

2026 Online Spanish Degree Programs for Veterans: GI Bill Benefits, Costs & Top Considerations
2026 Last-Minute Admissions: Online Social Work Advanced Standing Degree Master's Programs Still Accepting Students

2026 Last-Minute Admissions: Online Social Work Advanced Standing Degree Master's Programs Still Accepting Students
2026 Best Online Executive MBA Programs

2026 Best Online Executive MBA Programs
2026 Online Finance Degree Master's Programs with No GRE or GMAT Requirements

2026 Online Finance Degree Master's Programs with No GRE or GMAT Requirements
2026 Can You Get a Human Resource Management Degree Master's Without a Related Bachelor's Degree?

2026 Can You Get a Human Resource Management Degree Master's Without a Related Bachelor's Degree?
2026 Shortest Online Family Nurse Practitioner Degree Master's Programs That Pay Well: Cost, Time to Completion, and Salary Outlook

2026 Shortest Online Family Nurse Practitioner Degree Master's Programs That Pay Well: Cost, Time to Completion, and Salary Outlook
2026 Online Spanish Degree Master's Programs That Accept FAFSA

2026 Online Spanish Degree Master's Programs That Accept FAFSA
2026 Best Accelerated Construction Management Degree Programs Online

2026 Best Accelerated Construction Management Degree Programs Online
2026 How to Become a Caregiver: Certification Requirements in Louisiana

2026 How to Become a Caregiver: Certification Requirements in Louisiana
2026 PharmD vs. PhD vs. Master of Science in Pharmaceutical Sciences: Which Degree Should You Pursue?

2026 PharmD vs. PhD vs. Master of Science in Pharmaceutical Sciences: Which Degree Should You Pursue?
2026 Online Graphic Design Degree Programs Costs: Tuition & Fees

2026 Online Graphic Design Degree Programs Costs: Tuition & Fees
2026 Best Online Associate in Physical Therapy Assistant Programs

2026 Best Online Associate in Physical Therapy Assistant Programs
2026 Online Music Business Degree Programs Costs: Tuition & Fees

2026 Online Music Business Degree Programs Costs: Tuition & Fees
2026 International Relations vs. Political Science Degree: Explaining the Difference

2026 International Relations vs. Political Science Degree: Explaining the Difference
2026 Online Adult Gerontology Acute Care Nurse Practitioner Degree Programs Costs: Tuition & Fees

2026 Online Adult Gerontology Acute Care Nurse Practitioner Degree Programs Costs: Tuition & Fees
2026 Online Anthropology Degree Programs Costs: Tuition & Fees

2026 Online Anthropology Degree Programs Costs: Tuition & Fees
2026 Cheapest Online Advertising Master's Degrees That Pay Well: Tuition, Duration, and Earnings

2026 Cheapest Online Advertising Master's Degrees That Pay Well: Tuition, Duration, and Earnings
2026 Best Master’s Degree Programs in Data Analytics

2026 Best Master’s Degree Programs in Data Analytics
2026 Last-Minute Admissions: Online Teaching Degree Master's Programs Still Accepting Students

2026 Last-Minute Admissions: Online Teaching Degree Master's Programs Still Accepting Students