Timothy M. Willson

Overview

Best Publications

• An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

  Jürgen M. Lehmann;Linda B. Moore;Tracey A. Smith-Oliver;William O. Wilkison

  4882
  Citations

• The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

  Mercedes Ricote;Andrew C. Li;Andrew C. Li;Timothy M. Willson;Carolyn J. Kelly

  4537
  Citations

• Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

  Steven A. Kliewer;Scott S. Sundseth;Stacey A. Jones;Peter J. Brown

  2722
  Citations

• A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

  Steven A. Kliewer;James M. Lenhard;Timothy M. Willson;Inder Patel

  2555
  Citations

• Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

  Derek J. Parks;Steven G. Blanchard;Randy K. Bledsoe;Gyan Chandra

  2543
  Citations

• Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.

  R T Nolte;G B Wisely;S Westin;J E Cobb

  2443
  Citations

• The PPARs: from orphan receptors to drug discovery.

  Timothy M. Willson;Peter J. Brown;Daniel D. Sternbach;Brad R. Henke

  2435
  Citations

• A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

  Bryan Goodwin;Stacey A. Jones;Roger R. Price;Michael A. Watson

  2129
  Citations

• The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

  Jürgen M. Lehmann;David D. McKee;Michael A. Watson;Timothy M. Willson

  1920
  Citations

• An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

  Steven A Kliewer;John T Moore;Laura Wade;Jeff L Staudinger

  1868
  Citations

• The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

  Jeffrey Leonard Staudinger;Jeffrey Leonard Staudinger;Bryan Goodwin;Stacey A. Jones;Diane Hawkins-Brown

  1520
  Citations

• Activation of the Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway

  Jürgen M. Lehmann;Steven A. Kliewer;Linda B. Moore;Tracey A. Smith-Oliver

  1517
  Citations

• A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.

  Gabriel Pascual;Amy L. Fong;Sumito Ogawa;Amir Gamliel

  1503
  Citations

• Molecular Recognition of Fatty Acids by Peroxisome Proliferator–Activated Receptors

  H.Eric Xu;Millard H Lambert;Valerie G Montana;Derek J Parks

  1464
  Citations

• A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

  William R. Oliver;Jennifer L. Shenk;Mike R. Snaith;Caroline S. Russell

  1432
  Citations

• The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.

  Steven A. Kliewer;Bryan Goodwin;Timothy M. Willson

  1259
  Citations

• St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

  Linda B. Moore;Bryan Goodwin;Stacey A. Jones;G. Bruce Wisely

  1246
  Citations

• The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

  Stacey A. Jones;Linda B. Moore;Jennifer L. Shenk;G. Bruce Wisely

  1221
  Citations

• A unified nomenclature system for the nuclear receptor superfamily

  J. Auwerx;E. Baulieu;M. Beato;M. Becker-Andre

  1159
  Citations

• Synthetic LXR ligand inhibits the development of atherosclerosis in mice

  Sean B. Joseph;Elaine McKilligin;Liming Pei;Michael A. Watson

  1118
  Citations