D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 120 Citations 82,529 256 World Ranking 415 National Ranking 289

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Organic chemistry

His scientific interests lie mostly in Nuclear receptor, Peroxisome proliferator-activated receptor, Biochemistry, Receptor and Internal medicine. His Nuclear receptor research incorporates elements of Signal transduction, Cell biology and Orphan receptor. His work deals with themes such as Cancer research, Transcription factor, Glucose homeostasis, Adipogenesis and Peroxisome proliferator-activated receptor alpha, which intersect with Peroxisome proliferator-activated receptor.

His Receptor study incorporates themes from Homeostasis, Bioinformatics, Drug discovery, Peroxisome proliferator-activated receptor delta and Fibrate. His studies deal with areas such as Liver X receptor and Endocrinology as well as Internal medicine. His work on Hepatic stellate cell as part of general Endocrinology research is often related to Hepatic stellate cell activation, thus linking different fields of science.

His most cited work include:

  • An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ) (3395 citations)
  • The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation (3255 citations)
  • A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation (1922 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Nuclear receptor, Biochemistry, Receptor, Peroxisome proliferator-activated receptor and Stereochemistry. He has researched Nuclear receptor in several fields, including Orphan receptor and Cell biology. His Receptor study integrates concerns from other disciplines, such as Gene expression, Fibrate and Small molecule.

Peroxisome proliferator-activated receptor is a subfield of Internal medicine that Timothy M. Willson investigates. His biological study spans a wide range of topics, including Chemical synthesis and Ring. His Endocrinology research integrates issues from Cancer research and Peroxisome proliferator-activated receptor gamma.

He most often published in these fields:

  • Nuclear receptor (27.10%)
  • Biochemistry (27.73%)
  • Receptor (27.41%)

What were the highlights of his more recent work (between 2014-2021)?

  • Kinase (9.66%)
  • Computational biology (8.10%)
  • Cell biology (13.71%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Kinase, Computational biology, Cell biology, Drug discovery and Kinome. The subject of his Kinase research is within the realm of Biochemistry. Timothy M. Willson integrates Biochemistry with NAK in his research.

His work carried out in the field of Cell biology brings together such families of science as Tissue homeostasis and Receptor-mediated endocytosis. His work is dedicated to discovering how Kinome, Druggability are connected with Bromodomain, Transcription, Molecular biology, Transcription factor and Scaffold protein and other disciplines. The various areas that he examines in his Protein kinase A study include Cancer cell, Receptor, Angiogenesis and Recombinant DNA.

Between 2014 and 2021, his most popular works were:

  • The promise and peril of chemical probes. (443 citations)
  • Comprehensive characterization of the Published Kinase Inhibitor Set (178 citations)
  • Comprehensive characterization of the Published Kinase Inhibitor Set (178 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Organic chemistry

Timothy M. Willson spends much of his time researching Kinase, Cell biology, Biochemistry, Kinome and Drug discovery. The Kinase study combines topics in areas such as Chemical probe and In vitro. His Cell biology research includes themes of Chemokine, Innate immune system and Circadian clock, Circadian rhythm.

His Biochemistry study frequently links to adjacent areas such as Thiadiazoles. His Kinome study combines topics in areas such as Regulator, Entry into host and Subfamily. His Drug discovery research incorporates themes from Angiogenesis, Recombinant DNA, Cancer cell, Receptor and Computational biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann;Linda B. Moore;Tracey A. Smith-Oliver;William O. Wilkison.
Journal of Biological Chemistry (1995)

4732 Citations

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote;Andrew C. Li;Andrew C. Li;Timothy M. Willson;Carolyn J. Kelly.
Nature (1998)

4317 Citations

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Steven A. Kliewer;Scott S. Sundseth;Stacey A. Jones;Peter J. Brown.
Proceedings of the National Academy of Sciences of the United States of America (1997)

2638 Citations

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation

Steven A. Kliewer;James M. Lenhard;Timothy M. Willson;Inder Patel.
Cell (1995)

2494 Citations

The PPARs: from orphan receptors to drug discovery.

Timothy M. Willson;Peter J. Brown;Daniel D. Sternbach;Brad R. Henke.
Journal of Medicinal Chemistry (2000)

2358 Citations

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.

R T Nolte;G B Wisely;S Westin;J E Cobb.
Nature (1998)

2349 Citations

Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Derek J. Parks;Steven G. Blanchard;Randy K. Bledsoe;Gyan Chandra.
Science (1999)

2227 Citations

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin;Stacey A. Jones;Roger R. Price;Michael A. Watson.
Molecular Cell (2000)

1829 Citations

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

Jürgen M. Lehmann;David D. McKee;Michael A. Watson;Timothy M. Willson.
Journal of Clinical Investigation (1998)

1809 Citations

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

Steven A Kliewer;John T Moore;Laura Wade;Jeff L Staudinger.
Cell (1998)

1807 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Timothy M. Willson

Bart Staels

Bart Staels

University of Lille

Publications: 319

Frank J. Gonzalez

Frank J. Gonzalez

National Institutes of Health

Publications: 248

Jan-Åke Gustafsson

Jan-Åke Gustafsson

University of Houston

Publications: 191

Ronald M. Evans

Ronald M. Evans

Salk Institute for Biological Studies

Publications: 170

Walter Wahli

Walter Wahli

University of Lausanne

Publications: 154

Johan Auwerx

Johan Auwerx

École Polytechnique Fédérale de Lausanne

Publications: 131

Peter Tontonoz

Peter Tontonoz

University of California, Los Angeles

Publications: 117

Jeffrey M. Peters

Jeffrey M. Peters

Pennsylvania State University

Publications: 104

Christopher K. Glass

Christopher K. Glass

University of California, San Diego

Publications: 104

Stefano Fiorucci

Stefano Fiorucci

University of Perugia

Publications: 99

David J. Mangelsdorf

David J. Mangelsdorf

The University of Texas Southwestern Medical Center

Publications: 95

Wen Xie

Wen Xie

University of Pittsburgh

Publications: 93

Mitchell A. Lazar

Mitchell A. Lazar

University of Pennsylvania

Publications: 93

Michael Trauner

Michael Trauner

Medical University of Vienna

Publications: 89

Makoto Makishima

Makoto Makishima

Nihon University

Publications: 81

Laszlo Nagy

Laszlo Nagy

University of Debrecen

Publications: 79

Trending Scientists

Elliot K. Kolodner

Elliot K. Kolodner

IBM (United States)

Vinko Erceg

Vinko Erceg

Broadcom (United States)

Sharifah Rafidah Wan Alwi

Sharifah Rafidah Wan Alwi

University of Technology Malaysia

Sotiris Makris

Sotiris Makris

University of Patras

Samuel Krimm

Samuel Krimm

University of Michigan–Ann Arbor

Marco Aurélio Zezzi Arruda

Marco Aurélio Zezzi Arruda

State University of Campinas

Jow-Lay Huang

Jow-Lay Huang

National Cheng Kung University

Jayanta Das

Jayanta Das

Indian Institute of Technology Kharagpur

Seiji Yamaguchi

Seiji Yamaguchi

Shimane University

Carsten Bergmann

Carsten Bergmann

University of Freiburg

Josep V. Planas

Josep V. Planas

International Pacific Halibut Commission

Gunnar Skov Simonsen

Gunnar Skov Simonsen

University Hospital of North Norway

Mark M. Brinson

Mark M. Brinson

East Carolina University

Elisabet Londos

Elisabet Londos

Lund University

Steven J. Siegel

Steven J. Siegel

University of Southern California

Jennifer S. Silk

Jennifer S. Silk

University of Pittsburgh

Something went wrong. Please try again later.