D-Index & Metrics Best Publications
Biology and Biochemistry
Germany
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 103 Citations 38,593 910 World Ranking 904 National Ranking 66

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Biochemistry, Bromodomain, Kinase, Computational biology and Protein structure are his primary areas of study. As a part of the same scientific study, he usually deals with the Biochemistry, concentrating on Biophysics and frequently concerns with Enzyme activator. Bromodomain is a subfield of Acetylation that Stefan Knapp explores.

His study looks at the intersection of Acetylation and topics like Histone with Lysine. He has included themes like Phosphorylation and Drug discovery in his Kinase study. His Computational biology research is multidisciplinary, relying on both Genetics and Recombinant DNA.

His most cited work include:

  • Selective inhibition of BET bromodomains (2564 citations)
  • Selective inhibition of BET bromodomains (2564 citations)
  • Histone recognition and large-scale structural analysis of the human bromodomain family. (937 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Crystal structure, Bromodomain, Kinase, Biochemistry and Cell biology. Stefan Knapp combines subjects such as Biophysics and Stereochemistry with his study of Crystal structure. The study incorporates disciplines such as Chromatin and Computational biology in addition to Bromodomain.

His research in Computational biology intersects with topics in Genetics and Drug discovery. His Kinase study combines topics in areas such as Cancer research, Small molecule and Phosphorylation. His studies in Cell biology integrate themes in fields like Molecular biology and Transcription factor.

He most often published in these fields:

  • Crystal structure (31.90%)
  • Bromodomain (34.38%)
  • Kinase (31.61%)

What were the highlights of his more recent work (between 2018-2021)?

  • Kinase (31.61%)
  • Cell biology (29.32%)
  • Crystal structure (31.90%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Kinase, Cell biology, Crystal structure, Crystallography and Computational biology. His Kinase study is related to the wider topic of Biochemistry. His work carried out in the field of Cell biology brings together such families of science as Histone, Transcription factor, Gene and Lysine.

His research links Acetylation with Histone. As a member of one scientific family, Stefan Knapp mostly works in the field of Acetylation, focusing on Epigenetics and, on occasion, Chromatin and Cancer research. His Computational biology research is multidisciplinary, incorporating perspectives in Allosteric regulation, Nucleotide, Proto-oncogene tyrosine-protein kinase Src and Drug discovery.

Between 2018 and 2021, his most popular works were:

  • A chemical toolbox for the study of bromodomains and epigenetic signaling (29 citations)
  • A chemical toolbox for the study of bromodomains and epigenetic signaling (29 citations)
  • SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK). (25 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Stefan Knapp mainly investigates Kinase, Cell biology, Bromodomain, Cancer research and Computational biology. His study on Kinase is covered under Biochemistry. His Cell biology study incorporates themes from Receptor, Transcription factor and Thyroid.

His Bromodomain research integrates issues from Domain family and Regulation of gene expression. His Computational biology study integrates concerns from other disciplines, such as Nuclear receptor, Structure–activity relationship and Drug discovery. His BRD4 research focuses on BET inhibitor and how it connects with Programmed cell death.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Selective inhibition of BET bromodomains.

Panagis Filippakopoulos;Jun Qi;Sarah Picaud;Yao Shen.
Nature (2010)

3578 Citations

Histone recognition and large-scale structural analysis of the human bromodomain family.

Panagis Filippakopoulos;Sarah Picaud;Maria Mangos;Tracy Keates.
Cell (2012)

1393 Citations

Targeting bromodomains: epigenetic readers of lysine acetylation

Panagis Filippakopoulos;Stefan Knapp.
Nature Reviews Drug Discovery (2014)

983 Citations

Protein production and purification.

S Gräslund.
Nature Methods (2008)

898 Citations

The promise and peril of chemical probes.

Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell.
Nature Chemical Biology (2015)

674 Citations

Critical Residues for Structure and Catalysis in Short-chain Dehydrogenases/Reductases

Charlotta Filling;Kurt D. Berndt;Kurt D. Berndt;Jordi Benach;Stefan Knapp.
Journal of Biological Chemistry (2002)

621 Citations

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.

K. L. Kavanagh;K. Guo;James Edward Dunford;James Edward Dunford;James Edward Dunford;X. Wu.
Proceedings of the National Academy of Sciences of the United States of America (2006)

598 Citations

Linear Motif Atlas for Phosphorylation-Dependent Signaling

Martin Lee Miller;Martin Lee Miller;Lars Juhl Jensen;Francesca Diella;Claus Jørgensen.
Science Signaling (2008)

488 Citations

Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome

Alastair J. Barr;Emilie Ugochukwu;Wen Hwa Lee;Oliver N.F. King.
Cell (2009)

445 Citations

Bromodomains as therapeutic targets.

Susanne Muller;Panagis Filippakopoulos;Stefan Knapp.
Expert Reviews in Molecular Medicine (2011)

434 Citations

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