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Biology and Biochemistry

D-Index
84
Citations
31139
World Ranking
3267
National Ranking
1655

Overview

Ming-Ming Zhou is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions also in medicine. Zhou's work is further specialized within subfields such as molecular biology, oncology, hematology, physiology, and neurology.

The scientist's research covers multiple main topics, including:

  • Protein Degradation and Inhibitors
  • Genomics and Chromatin Dynamics
  • Multiple Myeloma Research and Treatments
  • Ubiquitin and proteasome pathways
  • Histone Deacetylase Inhibitors Research
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer

Ming-Ming Zhou has published extensively in recognized academic venues. The frequent publication venues include:

  • Nature Communications
  • PubMed
  • Medicinal Research Reviews
  • Biochemical Pharmacology
  • Drug Discovery Today

Among recent notable papers authored or co-authored by Zhou are:

  • "Artificial intelligence and machine learning-aided drug discovery in central nervous system diseases: State-of-the-arts and future directions" (2020) published in Medicinal Research Reviews
  • "Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease" (2020) published in Neuron
  • "Roles of the BRD4 short isoform in phase separation and active gene transcription" (2020) published in Nature Structural & Molecular Biology
  • "Minocycline promotes functional recovery in ischemic stroke by modulating microglia polarization through STAT1/STAT6 pathways" (2021) published in Biochemical Pharmacology
  • "The Functions of BET Proteins in Gene Transcription of Biology and Diseases" (2021) published in Frontiers in Molecular Biosciences

Frequent collaborators working with Ming-Ming Zhou include:

  • Ka Lung Cheung
  • Lei Zeng
  • Anbalagan Jaganathan
  • Chunhua Song
  • Xinye Han

Best Publications

  • Structure and ligand of a histone acetyltransferase bromodomain

    Christophe Dhalluin;Justin E. Carlson;Lei Zeng;Cheng He

  • Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

    Kyoko L. Yap;Side Li;Ana M. Muñoz-Cabello;Selina Raguz

  • Bromodomain: an acetyl-lysine binding domain

    Lei Zeng;Ming Ming Zhou

  • Hallucinogens Recruit Specific Cortical 5-HT2A Receptor-Mediated Signaling Pathways to Affect Behavior

    Javier González-Maeso;Noelia V. Weisstaub;Mingming Zhou;Pokman Chan

  • Identification of a serotonin/glutamate receptor complex implicated in psychosis

    Javier González-Maeso;Rosalind L. Ang;Tony Yuen;Pokman Chan

  • Reading protein modifications with interaction domains

    Bruce T Seet;Ivan Dikic;Ming-Ming Zhou;Tony Pawson;Tony Pawson

  • Structure and conserved RNA binding of the PAZ domain

    Kelley S. Yan;Sherry Yan;Amjad Farooq;Arnold Han

  • Structure and regulation of MAPK phosphatases.

    Amjad Farooq;Ming Ming Zhou

  • Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice

    Noelia V. Weisstaub;Mingming Zhou;Alena Lira;Evelyn Lambe;Evelyn Lambe

  • The PHD finger: a versatile epigenome reader

    Roberto Sanchez;Ming-Ming Zhou

  • Disrupting the Interaction of BRD4 With Diacetylated Twist Suppresses Tumorigenesis in Basal-Like Breast Cancer

    Jian Shi;Yifan Wang;Yifan Wang;Lei Zeng;Yadi Wu

  • Structure and ligand recognition of the phosphotyrosine binding domain of Shc.

    Ming-Ming Zhou;Kodimangalam S. Ravichandran;Edward T. Olejniczak;Andrew M. Petros

  • PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing.

    Alexey V. Ivanov;Hongzhuang Peng;Vyacheslav Yurchenko;Kyoko L. Yap

  • Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b

    Lei Zeng;Qiang Zhang;SiDe Li;Alexander N. Plotnikov

  • The role of human bromodomains in chromatin biology and gene transcription.

    Roberto Sanchez;Ming-Ming Zhou

  • Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

    Marta Barradas;Emma Anderton;Juan Carlos Acosta;Si De Li

  • Structural Mechanism of the Bromodomain of the Coactivator CBP in p53 Transcriptional Activation

    Shiraz Mujtaba;Yan He;Lei Zeng;Sherry Yan

  • Phosphothreonine recognition comes into focus.

    Ming-Ming Zhou

  • Transcriptome Fingerprints Distinguish Hallucinogenic and Nonhallucinogenic 5-Hydroxytryptamine 2A Receptor Agonist Effects in Mouse Somatosensory Cortex

    Javier González-Maeso;Tony Yuen;Barbara J. Ebersole;Elisa Wurmbach

  • Long Noncoding RNA, Polycomb, and the Ghosts Haunting INK4b-ARF-INK4a Expression

    Francesca Aguilo;Ming-Ming Zhou;Martin J. Walsh

Frequent Co-Authors

Lei Zeng
Lei Zeng Icahn School of Medicine at Mount Sinai
Herbert Lepor
Herbert Lepor New York University
Samir S. Taneja
Samir S. Taneja New York University
Samuel Waxman
Samuel Waxman Icahn School of Medicine at Mount Sinai
Timothy D. Veenstra
Timothy D. Veenstra Lake Erie College of Osteopathic Medicine
Jonathan Melamed
Jonathan Melamed New York University
Stephen W. Fesik
Stephen W. Fesik Vanderbilt University
Zhiyong Wang
Zhiyong Wang University of Science and Technology of China
Huabao Xiong
Huabao Xiong Icahn School of Medicine at Mount Sinai
Arthur Zelent
Arthur Zelent University of Miami

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