World's Best Scientists 2026 revealed!
John D. Brennan

John D. Brennan

D-Index & Metrics

Chemistry

D-Index
69
Citations
13197
World Ranking
6365
National Ranking
168

Overview

John D. Brennan is affiliated with McMaster University in Canada. Their research spans multiple scientific disciplines, with primary focuses in biochemistry, genetics, and molecular biology, as well as engineering and medicine. Within these fields, Brennan has contributed notably to molecular biology, biomedical engineering, infectious diseases, ecology, and physiology.

The main topics in Brennan's body of work include advanced biosensing and bioanalysis techniques, biosensors and analytical detection, bacteriophages and microbial interactions, SARS-CoV-2 detection and testing, SARS-CoV-2 and COVID-19 research, DNA and nucleic acid chemistry, and RNA and protein synthesis mechanisms.

Brennan has published extensively in the following venues:

  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Chemistry - A European Journal
  • Analysis & Sensing
  • Chemical Society Reviews

Some of Brennan's recent papers include:

  • Biosensing with DNAzymes, 2021, Chemical Society Reviews
  • High-Affinity Dimeric Aptamers Enable the Rapid Electrochemical Detection of Wild-Type and B.1.1.7 SARS-CoV-2 in Unprocessed Saliva, 2021, Angewandte Chemie International Edition
  • Diverse high-affinity DNA aptamers for wild-type and B.1.1.7 SARS-CoV-2 spike proteins from a pre-structured DNA library, 2021, Nucleic Acids Research
  • Functional nucleic acid biosensors utilizing rolling circle amplification, 2022, Chemical Society Reviews
  • Functional Nucleic Acids for Pathogenic Bacteria Detection, 2021, Accounts of Chemical Research

Brennan frequently collaborates with several researchers, including:

  • Yingfu Li
  • Jimmy Gu
  • Alfredo Capretta
  • Dawn White
  • Zijie Zhang

Best Publications

  • Properties and applications of proteins encapsulated within sol–gel derived materials

    Wen Jin;John D Brennan

  • Biosensing with DNAzymes

    Erin M. McConnell;Ioana Cozma;Quanbing Mou;John D. Brennan

  • Reagentless bidirectional lateral flow bioactive paper sensors for detection of pesticides in beverage and food samples

    S. M. Zakir Hossain;Roger E. Luckham;Meghan J. Mcfadden;John D. Brennan

  • β-Galactosidase-Based Colorimetric Paper Sensor for Determination of Heavy Metals

    S. M. Zakir Hossain;John D. Brennan

  • Development of a bioactive paper sensor for detection of neurotoxins using piezoelectric inkjet printing of sol-gel-derived bioinks.

    S. M. Zakir Hossain;Roger E. Luckham;Anne Marie Smith;Julie M. Lebert

  • An efficient RNA-cleaving DNA enzyme that synchronizes catalysis with fluorescence signaling.

    Shirley H J Mei;Zhongjie Liu;John D Brennan;Yingfu Li

  • Tools for water quality monitoring and mapping using paper-based sensors and cell phones.

    Clémence Sicard;Chad Glen;Brandon Aubie;Dan Wallace

  • Multiplexed paper test strip for quantitative bacterial detection.

    S. M. Zakir Hossain;Cory Ozimok;Clémence Sicard;Sergio D. Aguirre

  • Bridging the gap between in vitro and in vivo imaging: isostructural Re and 99mTc complexes for correlating fluorescence and radioimaging studies.

    Karin A. Stephenson;Sangeeta Ray Banerjee;Travis Besanger;Oyebola O. Sogbein

  • Unfolding of Acrylodan-Labeled Human Serum Albumin Probed by Steady-State and Time-Resolved Fluorescence Methods

    Kulwinder Flora;John D. Brennan;Gary A. Baker;Meagan A. Doody

  • Assemblage of signaling DNA enzymes with intriguing metal-ion specificities and pH dependences.

    Zhongjie Liu;Shirley H. J. Mei;John D. Brennan;Yingfu Li

  • Hydrophobic sol–gel channel patterning strategies for paper-based microfluidics

    Jingyun Wang;Maria Rowena N. Monton;Xi Zhang;Carlos D. M. Filipe

  • Fluorescent Probes as Reporters on the Local Structure and Dynamics in Sol−Gel-Derived Nanocomposite Materials

    Tracey Keeling-Tucker and;John D. Brennan

  • High-Affinity Dimeric Aptamers Enable the Rapid Electrochemical Detection of Wild-Type and B.1.1.7 SARS-CoV-2 in Unprocessed Saliva.

    Zijie Zhang;Richa Pandey;Jiuxing Li;Jimmy Gu

  • Sugar-modified silanes: precursors for silica monoliths

    Michael A. Brook;Yang Chen;Kui Guo;Zheng Zhang

  • A DNAzyme Feedback Amplification Strategy for Biosensing.

    Meng Liu;Qiang Zhang;Dingran Chang;Jimmy Gu

  • A graphene-based biosensing platform based on the release of DNA probes and rolling circle amplification.

    Meng Liu;Jinping Song;Jinping Song;Shaomin Shuang;Chuan Dong

  • A DNAzyme-Based Colorimetric Paper Sensor for Helicobacter pylori.

    M. Monsur Ali;Michael Wolfe;Kha Tram;Jimmy Gu

  • Tailoring Sol–Gel-Derived Silica Materials for Optical Biosensing

    Maria Rowena N. Monton;Erica M. Forsberg;John D. Brennan

  • Development and Scale-Up of a Continuous, High-Pressure, Asymmetric Hydrogenation Reaction, Workup, and Isolation

    Unknown

  • Target‐Induced and Equipment‐Free DNA Amplification with a Simple Paper Device

    Meng Liu;Christy Y. Hui;Qiang Zhang;Jimmy Gu

  • Paper-based microfluidics with an erodible polymeric bridge giving controlled release and timed flow shutoff

    Sana Jahanshahi-Anbuhi;Aleah Henry;Vincent Leung;Clémence Sicard

  • Creating fast flow channels in paper fluidic devices to control timing of sequential reactions

    Sana Jahanshahi-Anbuhi;Puneet Chavan;Clémence Sicard;Vincent Leung

Frequent Co-Authors

Yingfu Li
Yingfu Li McMaster University
Michael A. Brook
Michael A. Brook McMaster University
Ulrich J. Krull
Ulrich J. Krull University of Toronto
Robert Pelton
Robert Pelton McMaster University
Ben Richard Hughes
Ben Richard Hughes University of Hull
John Kaiser Calautit
John Kaiser Calautit University of Nottingham
Chuan Dong
Chuan Dong Shanxi University
Parameswaran Nair
Parameswaran Nair McMaster University
Gary A. Baker
Gary A. Baker University of Missouri
Frank V. Bright
Frank V. Bright University at Buffalo, State University of New York

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying chemistry in the USA opens doors to a variety of specialized career paths that often require further education and training. For those interested in healthcare, exploring the steps to become a pharmacist is essential. Pharmacists rely heavily on chemistry knowledge to develop and dispense medications safely, making it a rewarding path for chemistry graduates.

Another unique field combining chemistry with investigative work is forensic science. Many students now pursue a forensic science degree online, which provides flexibility while gaining expertise in applying chemical techniques to criminal investigations. This can also lead to roles such as an autopsy technician. Learning the how to become an autopsy technician process outlines the education and practical steps to work in medical examiner offices.

For those interested in understanding the psychological aspects behind criminal behavior, pursuing a masters in forensic psychology online offers advanced knowledge. This path combines chemistry, psychology, and criminal justice, further broadening career opportunities in forensic and legal settings.

Best Scientists Citing John D. Brennan

Trending Scientists