What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Biochemistry, Enzyme, Genetics, Histone and Histone Demethylases.
His Biochemistry study frequently draws connections to adjacent fields such as Stereochemistry.
His Stereochemistry research includes themes of Mevalonate pathway and Farnesyl pyrophosphate.
In his study, Transcription, Transcriptional regulation and High-throughput screening is strongly linked to Methylation, which falls under the umbrella field of Histone.
His Chromatin study incorporates themes from Hydroxylation, Subfamily, Chemoproteomics and Demethylase activity.
The Short-chain dehydrogenase study combines topics in areas such as Sequence motif, Sequence alignment, NAD+ kinase and Protein family.
His most cited work include:
- Protein production and purification. (655 citations)
- Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility (608 citations)
- A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response (599 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Biochemistry, Crystal structure, Stereochemistry, Crystallography and Enzyme.
His study in Active site, Dehydrogenase, Reductase, Oxidoreductase and Histone is carried out as part of his Biochemistry studies.
His Histone study combines topics in areas such as Chromatin and Cell biology.
In his study, Cancer research is inextricably linked to Epigenetics, which falls within the broad field of Chromatin.
Udo Oppermann interconnects Biophysics and Catalysis in the investigation of issues within Crystal structure.
His Enzyme study is mostly concerned with Short-chain dehydrogenase and Hydroxysteroid Dehydrogenases.
He most often published in these fields:
- Biochemistry (40.26%)
- Crystal structure (33.93%)
- Stereochemistry (29.06%)
What were the highlights of his more recent work (between 2016-2021)?
- Cancer research (10.88%)
- Epigenetics (10.55%)
- Chromatin (10.71%)
In recent papers he was focusing on the following fields of study:
Udo Oppermann mostly deals with Cancer research, Epigenetics, Chromatin, Cell biology and Histone.
His work deals with themes such as Endometriosis, Histone methyltransferase, Apoptosis, Amine oxidase and Mutant, which intersect with Cancer research.
His Epigenetics study results in a more complete grasp of Biochemistry.
Biochemistry is represented through his Histone Demethylases and Drug discovery research.
His Chromatin research also works with subjects such as
- Regulation of gene expression which connect with Gene silencing,
- Histone code most often made with reference to Methylation.
His Histone research is multidisciplinary, incorporating elements of Molecular biology, Mesenchymal stem cell, Genome instability and DNA methylation.
Between 2016 and 2021, his most popular works were:
- Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells (55 citations)
- Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells (55 citations)
- Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells. (38 citations)
In his most recent research, the most cited papers focused on:
Chromatin, Biochemistry, Cell biology, Epigenetics and Histone are his primary areas of study.
His study explores the link between Chromatin and topics such as Methylation that cross with problems in Histone code.
His study in Drug discovery, Transfer RNA, HSD17B10, RNase P and Enzyme falls within the category of Biochemistry.
Udo Oppermann combines subjects such as Cell, Transcription factor, Glucocorticoid receptor and Bromodomain with his study of Cell biology.
His research investigates the connection between Epigenetics and topics such as Demethylation that intersect with issues in Subfamily, IC50, Lysine and Molecular model.
His studies deal with areas such as Molecular biology and Retinoblastoma protein as well as Histone.
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