His primary areas of investigation include Stereochemistry, Biochemistry, Hydroxylation, Oxygenase and Organic chemistry. His Stereochemistry research is multidisciplinary, incorporating elements of Amino acid, Keramaphidin B and Biosynthesis. His work deals with themes such as Molecular biology, Hypoxia-inducible factors and Pharmacology, which intersect with Biochemistry.
He has included themes like Hypoxia-Inducible Factor 1 and Dioxygenase in his Hydroxylation study. His biological study spans a wide range of topics, including Protein hydroxylation and Nuclear protein. The study incorporates disciplines such as Oxidation reduction, Dynamic combinatorial chemistry, Medicinal chemistry and Combinatorial Chemistry Techniques in addition to Organic chemistry.
The scientist’s investigation covers issues in Stereochemistry, Biochemistry, Nuclear magnetic resonance spectroscopy, Organic chemistry and Enzyme. His Stereochemistry study integrates concerns from other disciplines, such as Amino acid, Enzyme catalysis, Catalysis, Active site and Ring. His Amino acid study combines topics from a wide range of disciplines, such as Tetrahydrofuran and Oxetane.
His studies in Ring integrate themes in fields like Crystallography and Nanoring. Biochemistry and Hypoxia-inducible factors are commonly linked in his work. His Nuclear magnetic resonance spectroscopy research incorporates elements of Combinatorial chemistry, Computational chemistry and Molecule.
His scientific interests lie mostly in Combinatorial chemistry, Metabolomics, Nuclear magnetic resonance spectroscopy, Multiple sclerosis and Fluorine-19 NMR. His studies deal with areas such as Catalysis, Enantioselective synthesis, Labelling and Metal, Metal binding as well as Combinatorial chemistry. His studies in Metabolomics integrate themes in fields like Quality, Internal medicine, Macromolecule and Nuclear magnetic resonance.
His Nuclear magnetic resonance spectroscopy research is multidisciplinary, incorporating elements of Coupling and Analytical technique. His research in Fluorine-19 NMR intersects with topics in Ferrous, Cooperativity and Carnitine biosynthesis, Biosynthesis. To a larger extent, he studies Stereochemistry with the aim of understanding Bicyclic molecule.
Timothy D. W. Claridge spends much of his time researching Nanoring, Ring, Aromaticity, Structure and Heteronuclear single quantum coherence spectroscopy. His Nanoring research includes elements of Chemical physics, Antiaromaticity and Porphyrin. His study focuses on the intersection of Antiaromaticity and fields such as Annulene with connections in the field of Nuclear magnetic resonance spectroscopy.
Timothy D. W. Claridge works mostly in the field of Porphyrin, limiting it down to topics relating to Proton NMR and, in certain cases, Fluorine-19 NMR, as a part of the same area of interest. His study on Structure is intertwined with other disciplines of science such as Two-dimensional nuclear magnetic resonance spectroscopy, Solution state, Computational chemistry, Small molecule and Homonuclear molecule. His Heteronuclear single quantum coherence spectroscopy research integrates issues from Biological system and Natural abundance.
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High-Resolution NMR Techniques in Organic Chemistry
Timothy D. W. Claridge.
(1999)
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
Rasheduzzaman Chowdhury;Kar Kheng Yeoh;Ya-Min Tian;Lars Hillringhaus.
EMBO Reports (2011)
Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.
Wai-Ching Hon;Michael I. Wilson;Karl Harlos;Timothy D. W. Claridge.
Nature (2002)
Vernier templating and synthesis of a 12-porphyrin nano-ring
Melanie C. O’Sullivan;Johannes K. Sprafke;Dmitry V. Kondratuk;Corentin Rinfray.
Nature (2011)
Inhibition of Human Leukocyte and Porcine Pancreatic Elastase by Homologues of Bovine Pancreatic Trypsin Inhibitor
James A. E. Kraunsoe;Timothy D. W. Claridge;Gordon Lowe.
Biochemistry (1996)
Unidirectional Photoinduced Shuttling in a Rotaxane with a Symmetric Stilbene Dumbbell
Carol A. Stanier;Sara J. Alderman;Tim D. W. Claridge;Harry L. Anderson.
Angewandte Chemie (2002)
Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803.
Luke A McNeill;Kirsty S Hewitson;Timothy D Claridge;Jürgen F Seibel.
Biochemical Journal (2002)
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
Tom H. Wright;Ben J. Bower;Justin M. Chalker;Gonçalo J. L. Bernardes.
Science (2016)
Fluorescent Charge-Assisted Halogen-Bonding Macrocyclic Halo-Imidazolium Receptors for Anion Recognition and Sensing in Aqueous Media
Fabiola Zapata;Antonio Caballero;Nicholas G. White;Tim D. W. Claridge.
Journal of the American Chemical Society (2012)
10-Helical conformations in oxetane β-amino acid hexamers
Timothy D.W Claridge;Jonathan M Goodman;Andres Moreno;Donald Angus.
Tetrahedron Letters (2001)
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