World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
103
Citations
37990
World Ranking
7383
National Ranking
721

Research.com Recognitions

  • 2011 - Fellow of the Royal Society of Edinburgh

Overview

Brian R. Walker is affiliated with Newcastle University in the United Kingdom and has a publication record primarily in the field of Medicine with a focus on Endocrinology, Diabetes, and Metabolism. Their research spans several subfields including Astronomy and Astrophysics, Oceanography, Physiology, and Behavioral Neuroscience.

The scientist's work covers a range of interconnected topics such as:

  • Hormonal Regulation and Hypertension
  • Solar and Space Plasma Dynamics
  • Geophysics and Gravity Measurements
  • Ionosphere and magnetosphere dynamics
  • Stress Responses and Cortisol
  • Adrenal Hormones and Disorders
  • Estrogen and related hormone effects

Recent papers authored by or involving Brian R. Walker demonstrate active engagement with glucocorticoid biology, cardiovascular disease risk, and new therapeutic approaches:

  • Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease (2021, Journal of Human Genetics)
  • Identification of human glucocorticoid response markers using integrated multi-omic analysis from a randomized crossover trial (2021, eLife)
  • The ATP-binding cassette proteins ABCB1 and ABCC1 as modulators of glucocorticoid action (2022, Nature Reviews Endocrinology)
  • Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy (2023, Cell Genomics)
  • Low dose dexamethasone as treatment for women with heavy menstrual bleeding: A response-adaptive randomised placebo-controlled dose-finding parallel group trial (DexFEM) (2021, EBioMedicine)

Brian R. Walker has frequently collaborated with several researchers including Ruth Andrew, Natalie Homer, Jim Fredrickson, H Wiley, and Eric A. Hill.

The scientist's publications are often featured in venues such as OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information), Journal of the Endocrine Society, bioRxiv (Cold Spring Harbor Laboratory), Endocrine Abstracts, and Endocrine Connections.

Recognition of their professional contributions includes election as a Fellow of the Royal Society of Edinburgh in 2011.

Best Publications

  • Minireview: 11β-Hydroxysteroid Dehydrogenase Type 1— A Tissue-Specific Amplifier of Glucocorticoid Action1

    Jonathan R. Seckl;Brian R. Walker

  • Glucocorticoids and insulin resistance: old hormones, new targets

    Robert C. Andrews;Brian R. Walker

  • Taking glucocorticoids by prescription is associated with subsequent cardiovascular disease.

    Li Wei;Thomas M. MacDonald;Brian R. Walker

  • Tissue-specific dysregulation of cortisol metabolism in human obesity.

    Eva Rask;Tommy Olsson;Stefan Soderberg;Ruth Andrew

  • Elevated plasma cortisol concentrations: a link between low birth weight and the insulin resistance syndrome?

    D. I. W. Phillips;D. J. P. Barker;C. H. D. Fall;J. R. Seckl

  • Randomised comparison of percutaneous angioplasty vs continued medical therapy for hypertensive patients with atheromatous renal artery stenosis. Scottish and Newcastle Renal Artery Stenosis Collaborative Group.

    J Webster;F Marshall;M Abdalla;A Dominiczak

  • Adrenocortical, Autonomic, and Inflammatory Causes of the Metabolic Syndrome Nested Case-Control Study

    E.J. Brunner;H. Hemingway;B.R. Walker;M. Page

  • Glucocorticoids and Cardiovascular Disease

    Brian R Walker

  • Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

    Nicholas M. Morton;Janice M. Paterson;Hiroaki Masuzaki;Megan C. Holmes

  • The intergenerational effects of fetal programming: non-genomic mechanisms for the inheritance of low birth weight and cardiovascular risk

    A J Drake;B R Walker

  • Genome-wide associations for birth weight and correlations with adult disease

    Momoko Horikoshi;Robin N. Beaumont;Felix R. Day;Nicole M. Warrington;Nicole M. Warrington

  • Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11beta-hydroxysteroid dehydrogenase type 1 activity.

    Eva Rask;Brian R Walker;Stefan Söderberg;Dawn E W Livingstone

  • Use of oral glucocorticoids and risk of cardiovascular and cerebrovascular disease in a population based case–control study

    P C Souverein;A Berard;T P Van Staa;C Cooper

  • Low Birth Weight Predicts Elevated Plasma Cortisol Concentrations in Adults From 3 Populations

    David I. W. Phillips;Brian R. Walker;Rebecca M. Reynolds;Daniel E. H. Flanagan

  • Health Status of Adults with Congenital Adrenal Hyperplasia: A Cohort Study of 203 Patients

    Wiebke Arlt;Debbie S. Willis;Sarah H. Wild;Nils Krone

  • Reduced Cortisol Metabolism during Critical Illness

    Eva Boonen;Hilke Vervenne;Philippe Meersseman;Ruth Andrew

  • Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source

    You-Ying Chau;Roberto Bandiera;Alan Serrels;Ofelia M. Martínez-Estrada

  • Glucocorticoids and fatty acid metabolism in humans: fuelling fat redistribution in the metabolic syndrome

    David P Macfarlane;Shareen Forbes;Brian R Walker

  • Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure.

    J. P. Noon;B. R. Walker;D. J. Webb;A. C. Shore

  • Understanding the role of glucocorticoids in obesity: tissue-specific alterations of corticosterone metabolism in obese Zucker rats.

    Dawn E. W. Livingstone;Gregory C. Jones;Ken Smith;Pauline M. Jamieson

Frequent Co-Authors

Jonathan R. Seckl
Jonathan R. Seckl University of Edinburgh
David J. Webb
David J. Webb University of Edinburgh
Tommy Olsson
Tommy Olsson Umeå University
Richard J. Ross
Richard J. Ross University of Sheffield
Wiebke Arlt
Wiebke Arlt University of Birmingham
Christopher Shaw
Christopher Shaw King's College London
Andrew Weeks
Andrew Weeks University of Liverpool
Andrew P. Morris
Andrew P. Morris University of Liverpool
Sarah Cunningham-Burley
Sarah Cunningham-Burley University of Edinburgh
Gudmundur Johannsson
Gudmundur Johannsson Sahlgrenska University Hospital

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring alternative healthcare degrees can broaden your career prospects beyond traditional medical school. Many online programs offer flexible options for those interested in specialized areas or leadership roles.

Psychiatric care is one fast-growing field. If you’re considering mental health, psychiatric np programs provide streamlined, online pathways to become a certified nurse practitioner specializing in psychiatric mental health.

For those more interested in healthcare leadership or management, pursuing a health care administration online degree can prepare you for roles in hospitals, clinics, or insurance companies. You can also find many online mha programs affordable enough to make earning a Master’s in Healthcare Administration accessible for more students.

Aspiring to reach the highest level of clinical practice? Several universities now offer the most affordable dnp programs online, allowing registered nurses to become Doctor of Nursing Practice graduates without leaving their jobs.

These degrees offer diverse routes to impactful healthcare careers—often with greater flexibility, affordability, and work–study balance.

Best Scientists Citing Brian R. Walker

Trending Scientists

Recently Published Articles