World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
14470
World Ranking
11283
National Ranking
867

Chemistry

D-Index
59
Citations
13917
World Ranking
10061
National Ranking
573

Alessio Ciulli publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Alessio Ciulli sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 249 publications — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Alessio Ciulli D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Alessio Ciulli sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 59 D-Index — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Alessio Ciulli is affiliated with the University of Dundee in the United Kingdom. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, contributing extensively to the understanding of molecular mechanisms in these fields.

The scientist has contributed 171 publications in the broad area of Biochemistry, Genetics and Molecular Biology, with significant overlap into Medicine through 70 publications. Subfields of their work include molecular biology (169 publications), oncology (47 publications), hematology (17 publications), organic chemistry (5 publications), and computational theory and mathematics (2 publications).

Key topics examined in their research emphasize protein degradation and inhibitors (152 publications), ubiquitin and proteasome pathways (114 publications), and peptidase inhibition and analysis (80 publications). Other topics include multiple myeloma research and treatments (34 publications), histone deacetylase inhibitors research (20 publications), chromatin remodeling and cancer (10 publications), and click chemistry and applications (10 publications).

They have published in a range of scientific journals, with frequent venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • RSC Medicinal Chemistry
  • Nature Chemical Biology
  • Journal of the American Chemical Society

Collaborations are a notable part of the scientist's work, with frequent co-authors being:

  • Andrea Testa (18 joint publications)
  • William Farnaby (14 joint publications)
  • Conner Craigon (13 joint publications)
  • Nikolai Makukhin (11 joint publications)
  • Adam G. Bond (11 joint publications)

Representative recent papers illustrate the focal areas of their research:

  • "E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones" (2020) published in SLAS DISCOVERY
  • "Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity" (2021) published in Nature Chemical Biology
  • "A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo" (2022) published in Nature Communications
  • "Discovery of small molecule ligands for the von Hippel-Lindau (VHL) E3 ligase and their use as inhibitors and PROTAC degraders" (2022) published in Chemical Society Reviews
  • "Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood-Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2" (2022) published in Journal of the American Chemical Society

Best Publications

  • Structural basis of PROTAC cooperative recognition for selective protein degradation.

    Morgan S Gadd;Andrea Testa;Xavier Lucas;Kwok-Ho Chan

  • Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4

    Michael Zengerle;Kwok-Ho Chan;Alessio Ciulli

  • Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interaction.

    Dennis L. Buckley;Inge Van Molle;Peter C. Gareiss;Hyun Seop Tae

  • BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design.

    William Farnaby;Manfred Koegl;Michael J. Roy;Claire Whitworth

  • Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities.

    Carles Galdeano;Morgan Stuart Gadd;Pedro Soares;Salvatore Scaffidi

  • Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7

    Vittoria Zoppi;Vittoria Zoppi;Scott J. Hughes;Chiara Maniaci;Andrea Testa

  • SPR-Measured Dissociation Kinetics of PROTAC Ternary Complexes Influence Target Degradation Rate.

    Michael J Roy;Sandra Winkler;Scott J Hughes;Claire Whitworth

  • E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones.

    Tasuku Ishida;Alessio Ciulli

  • Small‐Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

    Dennis L. Buckley;Jeffrey L. Gustafson;Inge Van Molle;Anke G. Roth

  • Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds

    Kwok Ho Chan;Michael Zengerle;Andrea Testa;Alessio Ciulli

  • A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

    Unknown

  • Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation

    Chiara Maniaci;Scott J. Hughes;Andrea Testa;Wenzhang Chen

  • Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition

    Julianty Frost;Carles Galdeano;Carles Galdeano;Pedro Soares;Morgan S. Gadd

  • Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.

    Emil Bulatov;Alessio Ciulli

  • Discovery of small molecule ligands for the von Hippel-Lindau (VHL) E3 ligase and their use as inhibitors and PROTAC degraders

    Unknown

  • Structure-Based Design of a Macrocyclic PROTAC.

    Andrea Testa;Scott J. Hughes;Xavier Lucas;Xavier Lucas;Jane E. Wright

  • Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity.

    Satomi Imaide;Kristin M. Riching;Nikolai Makukhin;Vesna Vetma

  • Molecular recognition of ternary complexes: a new dimension in the structure-guided design of chemical degraders.

    Scott J. Hughes;Alessio Ciulli

  • Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein Interface

    Inge Van Molle;Andreas Thomann;Dennis L. Buckley;Ernest C. So

  • Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood–Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2

    Unknown

  • Probing hot spots at protein-ligand binding sites: a fragment-based approach using biophysical methods.

    Alessio Ciulli;Glyn Williams;Alison G. Smith;Tom L. Blundell

  • Cyclic and Macrocyclic Peptides as Chemical Tools To Recognise Protein Surfaces and Probe Protein-Protein Interactions.

    Teresa A. F. Cardote;Alessio Ciulli

  • Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase: Structure–Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)

    Pedro Soares;Morgan S. Gadd;Julianty Frost;Carles Galdeano

  • Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

    Martin Philpott;Jing Yang;Tony Tumber;Oleg Fedorov

Frequent Co-Authors

Chris Abell
Chris Abell University of Cambridge
Tom L. Blundell
Tom L. Blundell University of Cambridge
Craig M. Crews
Craig M. Crews Yale University
Sonia Rocha
Sonia Rocha University of Liverpool
Panagis Filippakopoulos
Panagis Filippakopoulos Structural Genomics Consortium
Oleg Fedorov
Oleg Fedorov University of Oxford
Stefan Knapp
Stefan Knapp Goethe University Frankfurt
Alison G. Smith
Alison G. Smith University of Cambridge
Dario R. Alessi
Dario R. Alessi University of Dundee
Francesco Bertoni
Francesco Bertoni Institute of Oncology Research

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